Januvia (Sitagliptin) belongs to the group of Diabetes medications called DPP-4 inhibitors. It works by increasing the amount of incretin released by the intestine. Incretin is a hormone that raises insulin levels when blood sugar is high and decreases the amount of sugar made by the body. Januvia (Sitagliptin) is used alone or in combination with other medications to impr...More on Januvia indication

Contrave contains two ingredients: naltrexone and bupropion. Naltrexone is a pure opioid antagonist. Bupropion belongs to the family of antidepressants. Together, they work in different areas of the brain to control appetite and cravings. Together, they are used in addition to exercise and a reduced-calorie diet to help reduce weight for adults who are clinically obese...More on Contrave indication

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Januvia (Sitagliptin). If you are concerned about side effects, discuss the risks and benefits of Januvia (Sitagliptin) with your...More on Januvia side effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Contrave. If you are concerned about side effects, discuss the risks and benefits of Contrave with your doctor. The following...More on Contrave side effects

Januvia (Sitagliptin) should not be taken by anyone who is allergic to Januvia (Sitagliptin) or to any of the ingredients of the medication....More on Januvia contraindications

Do not take Contrave if you: are allergic to naltrexone, bupropion, or any ingredients of Contrave are pregnant are taking another medication that contains bupropion (e.g., Wellbutrin XL®, Wellbutrin® SR, or Zyban®) are currently taking thioridazine (an antipsychotic medication) are receiving opiate analgesics (e.g., narcotics medications such as oxycodone and codeine) or opiate...More on Contrave contraindications

There may be an interaction between Januvia (Sitagliptin) and any of the following: acetazolamide alcohol alpha-lipoic acids angiotensin converting enzyme inhibitors (ACEIs; captopril, enalapril, ramipril) antimalarial medications (e.g., hydroxychloroquine, quinine) antipsychotics (e.g., aripiprazole, clozapine, quetiapine, risperidone) beta-blockers (e.g., acebutolol, carvedilol, metoprol...More on Januvia precautions

There may be an interaction between naltrexone – bupropion and any of the following: alcohol amantadine amphetamines (dextroamphetamine, lisdexamfetamine) antipsychotics (e.g., amoxapine, chlorpromazine, haloperidol, pimozide, risperidone, thioridazine) apomorphine atomoxetine bromocriptine caffeine carbamazepine carvedilol clopidogrel dexmethylphenidate dextromethorphan dig...More on Contrave precautions