Dornase alfa is a medication that is used in combination with other medications to treat Cystic Fibrosis. It is used to reduce the risk of respiratory tract infections (e.g., Bronchitis, pneumonia) and to improve lung function. It works by breaking up DNA (genetic material) in sputum, making it less thick and easier to clear from the lungs.

Your doctor may have suggested Pulmozyme (Dornase-alfa) for conditions other than those listed in these drug information articles. As well, some forms of Pulmozyme (Dornase-alfa) may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Pulmozyme (Dornase-alfa), speak to your doctor. Do not stop taking Pulmozyme (Dornase-alfa) without consulting your doctor.

Do not give Pulmozyme (Dornase-alfa) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Pulmozyme (Dornase-alfa) if their doctor has not prescribed it.

Automatic Refills

We manage your refills and get in touch with your doctors for prescription renewals so that you always have the medication you need.

The usual dose of Pulmozyme (Dornase-alfa) is one 2.5 mg ampule inhaled once a day using the recommended nebulizer. Some people may use Pulmozyme (Dornase-alfa) twice a day if recommended by their doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use Pulmozyme (Dornase-alfa) exactly as prescribed by your doctor and that you understand how to use and maintain the nebulizer. Read the patient instructions provided and talk to your doctor or pharmacist if you are not sure how to use Pulmozyme (Dornase-alfa) properly. Use the nebulizer and mouthpiece that is recommended or provided to you. Do not mix Pulmozyme (Dornase-alfa) with any other medication in the nebulizer. Before using an ampule, squeeze it to ensure it does not leak. Pulmozyme (Dornase-alfa) contains no preservative and once an ampule is opened, the entire content must be used or discarded.

If you miss a dose, use it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Pulmozyme (Dornase-alfa) in the refrigerator, protect it from light, and keep it out of the reach of children.

Pulmozyme (Dornase-alfa) should be kept refrigerated during travelling and should not be at room temperature for more than 24 hours. If you notice that the solution is cloudy or discoloured, do not use it and discard it.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Pulmozyme (Dornase-alfa). If you are concerned about side effects, discuss the risks and benefits of Pulmozyme (Dornase-alfa) with your doctor.

The following side effects have been reported by at least 1% of people taking Pulmozyme (Dornase-alfa). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• chest pain
• cough
• difficulty breathing
• Fever
• heartburn
• Laryngitis
• rash
• red eyes or swelling of the eyelids
• runny nose
• sore throat
• voice changes

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Stop taking the medication and seek immediate medical attention if any of the following occur:

• signs of a Anaphylaxis (severe allergic reaction) (e.g., Hives; difficulty breathing; swelling of the face, mouth, tongue, or throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Pulmozyme (Dornase-alfa).

Free Delivery

Your medication is delivered directly to you at no added cost. We even offer same-day delivery in select locations.

Each ampule of sterile, clear, colourless, aqueous solution contains dornase alfa 1 mg/mL (2.5 mg). Nonmedicinal ingredients: calcium chloride dihydrate, sodium chloride, and sterile water for injection. Pulmozyme (Dornase-alfa) does not contain any preservatives.

Do not use Pulmozyme (Dornase-alfa) if you:

• are allergic to dornase alfa or any ingredients of Pulmozyme (Dornase-alfa)
• are allergic to Chinese hamster ovary cell products

Discreet Packaging

Your privacy is important. That's why we send your medication inside a plain delivery box so no one will know what's inside.

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Pulmozyme (Dornase-alfa).

Pregnancy: Pulmozyme (Dornase-alfa) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Pulmozyme (Dornase-alfa), contact your doctor.

Breast-feeding: It is not known if dornase alfa passes into breast milk. If you are a breast-feeding mother and are using Pulmozyme (Dornase-alfa), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Pulmozyme (Dornase-alfa) have not been established for children less than 5 years old.

Personalized PocketPacks

We sort your medication into clearly labeled, individual packs so you can be sure you're taking the right dose at the right time.