Trifluridine belongs to a group of medications known as antivirals. It is used to treat certain Eye Infections caused by herpes simplex virus types 1 and 2. It works by killing the virus that causes the infection.

Your doctor may have suggested Sandoz Trifluridine (Trifluridine-eent) for conditions other than the ones listed in these drug information articles. As well, some forms of Sandoz Trifluridine (Trifluridine-eent) may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are using Sandoz Trifluridine (Trifluridine-eent), speak to your doctor. Do not stop using Sandoz Trifluridine (Trifluridine-eent) without consulting your doctor.

Do not give Sandoz Trifluridine (Trifluridine-eent) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use Sandoz Trifluridine (Trifluridine-eent) if their doctor has not prescribed it.

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The usual recommended adult dose of trifluridine eye drops is 1 drop into the affected eye(s) (on the cornea) every 2 hours while awake (up to a maximum of 9 drops per day). This dose is continued until the eye lesion heals over, usually within 7 to 14 days. Then, the usual dose is 1 drop into the affected eye(s) every 4 hours (up to a maximum of 5 drops per day) while awake for 7 days. The medication should not be used for longer than 21 days. If no improvement is seen in 7 days, or if the lesion has not healed within 14 days, see your doctor.

Before instilling these eye drops, wash your hands thoroughly with soap and warm water. To avoid contaminating the eye drops, do not touch the tip of the dropper to any surface, including your eye or finger.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use Sandoz Trifluridine (Trifluridine-eent) exactly as prescribed by your doctor. If you miss a dose, instill it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not instill a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Sandoz Trifluridine (Trifluridine-eent) in the refrigerator at 2°C to 8°C (do not allow to freeze), protect it from light, and keep it out of the reach of children.

Sandoz Trifluridine (Trifluridine-eent) is available under multiple brand names and/or in several different forms. Any specific brand name of Sandoz Trifluridine (Trifluridine-eent) may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does Sandoz Trifluridine (Trifluridine-eent) come in?"

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who uses Sandoz Trifluridine (Trifluridine-eent). If you are concerned about side effects, discuss the risks and benefits of Sandoz Trifluridine (Trifluridine-eent) with your doctor.

The following side effects have been reported by at least 1% of people using Sandoz Trifluridine (Trifluridine-eent). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• burning or stinging
• mild irritation of the eye
• swelling and redness of the eyelid

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention

Check with your doctor as soon as possible if any of the following side effects occur:

• itching, redness, swelling, or other sign of irritation not present before use of Sandoz Trifluridine (Trifluridine-eent)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• signs of an allergic reaction (e.g., skin itching, rash, redness, swelling, or Hives)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Sandoz Trifluridine (Trifluridine-eent).

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Each mL of sterile, ophthalmic solution contains trifluridine 10 mg (1%). Nonmedicinal ingredients: acetic acid, benzalkonium chloride as preservative, sodium acetate, sodium chloride, and water for injection.

Trifluridine should not be used by anyone who is allergic to trifluridine or to any of the ingredients of the medication.

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There may be an interaction between trifluridine and any of the following:

• other eye drops

If you are using any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Sandoz Trifluridine (Trifluridine-eent). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Sandoz Trifluridine (Trifluridine-eent)

Pregnancy: Sandoz Trifluridine (Trifluridine-eent) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Sandoz Trifluridine (Trifluridine-eent), contact your doctor immediately.

Breast-feeding: It is not known if trifluridine passes into breast milk. If you are a breast-feeding mother and are using Sandoz Trifluridine (Trifluridine-eent), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Sandoz Trifluridine (Trifluridine-eent) have not been established for children.

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