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Singulair (Montelukast) belongs to a group of medications known as leukotriene receptor antagonists. It is used to prevent and manage Asthma symptoms and to relieve the symptoms of seasonal Allergies, also known as seasonal Allergic Rhinitis or hay Fever.
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Singulair (Montelukast) belongs to a group of medications known as leukotriene receptor antagonists. It is used to prevent and manage Asthma symptoms and to relieve the symptoms of seasonal Allergies, also known as seasonal Allergic Rhinitis or hay Fever. It may also be used to treat asthma symptoms caused by exercise (exercise-induced bronchoconstriction). It works by blocking the effects of leukotrienes, a substance produced by the body in response to certain "triggers" that cause narrowing and swelling of airways in the lungs. It may be taken alone or in addition to other asthma medications. Singulair (Montelukast) usually starts to work within one day.
When used to prevent and manage asthma, it is important to understand that Singulair (Montelukast) should not be used to relieve an asthma attack once it has started. People with asthma should always have their fast-acting asthma relief medication on hand to treat an asthma attack.
Your doctor may have suggested Singulair (Montelukast) for conditions other than the ones listed in these drug information articles. As well, some forms of Singulair (Montelukast) may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Singulair (Montelukast), speak to your doctor. Do not stop taking Singulair (Montelukast) without consulting your doctor.
Do not give Singulair (Montelukast) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Singulair (Montelukast) if their doctor has not prescribed it.
For seasonal allergic rhinitis, the recommended dose of Singulair (Montelukast) for adults and adolescents 15 years and older is one 10 mg tablet taken once a day in the evening.
For asthma, the recommended dose of Singulair (Montelukast) for adults and adolescents 15 years and older is one 10 mg tablet taken once a day in the evening. For children 6 to 14 years old, the recommended dose is one chewable 5 mg tablet taken once a day in the evening. For children 2 to 5 years old, the recommended dose is one chewable 4 mg tablet or one packet of 4 mg granules taken in the evening.
Singulair (Montelukast) can be taken with or without food.
The oral granules can be given either directly in the mouth, or mixed with a spoonful of cold or room temperature soft food (e.g., apple sauce). The packet should not be opened until ready to use. After opening the packet, the full dose of oral granules must be given within 15 minutes. Do not store any oral granule and food mixture for later use. Do not mix the oral granules in liquid. Children may drink liquids after swallowing the oral granules.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Singulair (Montelukast) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Singulair (Montelukast) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Singulair (Montelukast). If you are concerned about side effects, discuss the risks and benefits of Singulair (Montelukast) with your doctor.
The following side effects have been reported by at least 1% of people taking Singulair (Montelukast). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Singulair (Montelukast).
Tablets
10 mg
Each beige, rounded square-shaped, film-coated tablet, with the code "MSD 117" on one side and "SINGULAIR" on the other, contains 10.4 mg of Singulair (Montelukast) sodium, which is the molar equivalent of 10 mg of free acid. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, and microcrystalline cellulose; film-coating: carnauba wax, hydroxypropyl cellulose, hydroxypropyl methylcellulose, red ferric oxide, titanium dioxide, and yellow ferric oxide.
Chewable Tablets
4 mg
Each pink, oval, biconvex-shaped, chewable tablet, with the code "MSD 711" on one side and "SINGULAIR" on the other, contains 4.2 mg of Singulair (Montelukast) sodium, which is the molar equivalent to 4 mg of free acid. Nonmedicinal ingredients: aspartame, cherry flavour, croscarmellose sodium, hydroxypropyl cellulose, magnesium stearate, mannitol, microcrystalline cellulose, and red ferric oxide.
5 mg
Each pink, round, biconvex-shaped, chewable tablet, with the code "MSD 275" on one side and "SINGULAIR" on the other, contains 5.2 mg of Singulair (Montelukast) sodium, which is the molar equivalent to 5 mg of free acid. Nonmedicinal ingredients: aspartame, cherry flavour, croscarmellose sodium, hydroxypropyl cellulose, magnesium stearate, mannitol, microcrystalline cellulose, and red ferric oxide.
Granules
Each 4 mg packet of oral granules (presented as a white, coarse, granular, free-flowing homogeneous solid in a foil packet) contains 4.2 mg of Singulair (Montelukast) sodium, which is the molar equivalent to 4 mg of free acid. Nonmedicinal ingredients: hydroxypropyl cellulose, magnesium stearate, and mannitol.
Do not take Singulair (Montelukast) if you are allergic to Singulair (Montelukast) or any ingredients of the medication.
There may be an interaction between Singulair (Montelukast) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Singulair (Montelukast). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking.
Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Singulair (Montelukast).
Asthma attacks and asthma control: The effectiveness of Singulair (Montelukast) in treating acute asthma attacks has not been established. You should not use it to treat an acute asthma attack – have your rescue medication ready in case of an acute attack. Do not stop taking Singulair (Montelukast) without consulting your doctor. For Singulair (Montelukast) to be effective, it is important to take it regularly on a daily basis, even if you feel your asthma is under control, unless otherwise directed by your doctor.
If you feel your asthma symptoms are not improving or are getting worse while taking Singulair (Montelukast), contact your doctor. If your asthma is made worse by acetylsalicylic acid (Asa), do not take ASA or other nonsteroidal anti-inflammatory medications (NSAIDS; e.g., Ibuprofen, Ketoprofen, Naproxen). If your asthma is made worse by exercise, continue to use the medications your doctor has prescribed before exercise.
Behaviour changes: Some people have reported changes in behaviour associated with taking Singulair (Montelukast). There have been occasional reports of aggressive behaviour or hostility, anxiousness, disorientation, decreased memory, sleep disturbances, or suicidal thoughts and behaviour. If you experience any of these effects or notice them in a family member who is taking Singulair (Montelukast) contact your doctor as soon as possible.
Depression: Singulair (Montelukast) has been associated with mood swings and symptoms of depression. If you have depression or a history of depression, discuss with your doctor how Singulair (Montelukast) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Singulair (Montelukast), and whether any special monitoring is needed.
If you experience symptoms of depression such as poor concentration, changes in weight, changes in sleep, decreased interest in activities, or notice them in a family member who is taking Singulair (Montelukast), contact your doctor as soon as possible.
Phenylketonuria: The chewable tablet form of Singulair (Montelukast) contains aspartame, an artificial sweetener which contains phenylalanine. The 4 mg chewable tablet contains 0.674 mg of phenylalanine, and the 5 mg chewable tablet contains 0.842 mg. People with phenylketonuria are unable to break phenylalanine down to get rid of it. If you have phenylketonuria, talk to your doctor about other alternatives.
Liver function: Liver disease or reduced liver function may cause Singulair (Montelukast) to build up in the body, causing side effects. The safety of using Singulair (Montelukast) for people with severely reduced liver function has not been established. If you have reduced liver function, discuss with your doctor how Singulair (Montelukast) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Singulair (Montelukast), and whether any special monitoring is needed.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Pregnancy: Singulair (Montelukast) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Singulair (Montelukast), contact your doctor immediately.
Breast-feeding: It is not known if Singulair (Montelukast) passes into breast milk. If you are a breast-feeding mother and are taking Singulair (Montelukast), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of Singulair (Montelukast) have not been established for children under 2 years old. Singulair (Montelukast) can be used to treat asthma for children aged 2 years and older and to treat seasonal allergies for adolescents 15 years and older.
References
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