Many medications can cause side effects. A side effect is an unwanted response to a medication when it is used in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who uses Apo Flunisolide (Flunisolide-nasal). If you are concerned about side effects, discuss the risks and benefits of Apo Flunisolide (Flunisolide-nasal) with your doctor.

The following side effects have been reported by at least 1% of people using Apo Flunisolide (Flunisolide-nasal). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• changes in the sense of smell or taste
• hoarseness
• irritation of the nose
• irritation of throat
• nasal burning or stinging
• nosebleeds
• sore throat

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• nosebleeds (repeated)
• yellow or green-coloured nasal discharge

Stop using the medication and seek immediate medical attention if any of the following occur:

• symptoms of a Anaphylaxis (severe allergic reaction) (e.g., swelling of eyes, throat, or face; skin rash; Hives; difficulty breathing)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Apo Flunisolide (Flunisolide-nasal).

Each metered spray of solution contains approximately 25 µg of flunisolide dissolved in an aqueous solution (0.025%). Nonmedicinal ingredients: benzalkonium chloride, butylated hydroxytoluene, citric acid (anhydrous), edetate disodium dihydrate, hydrochloric acid, polyethylene glycol, polysorbate 20 (Tween 20), purified water, sodium citrate (dihydrate), sodium hydroxide, and sorbitol (crystalline fines).

Do not use this mediction if you:

• are allergic to flunisolide or to any of the ingredients of the medication
• are under the age of 6 years
• have active or inactive Tuberculosis
• have untreated fungal, bacterial, or viral infections

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Apo Flunisolide (Flunisolide-nasal).

Infection: Corticosteroids such as flunisolide can mask the signs of infection. You can also develop other infections such as a fungal throat infection. Talk to your doctor as soon as possible if you develop any new symptoms.

Long-term treatment: If you have been using Apo Flunisolide (Flunisolide-nasal) for long periods of time, your doctor should reassess your condition periodically to determine if continued treatment is necessary.

Medical conditions: If you have Asthma, Thyroid problems, liver disease, or a history of frequent nosebleeds, discuss with your doctor how Apo Flunisolide (Flunisolide-nasal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Flunisolide (Flunisolide-nasal), and whether any special monitoring is needed.

Other corticosteroid medications: If you have been taking oral corticosteroids and are starting flunisolide, your doctor should carefully monitor your condition. Changing from the oral form to the nasal spray can cause symptoms such as tiredness, aches, pains, and Depression. Tell your doctor if you have used or are using other corticosteroids. Your doctor will monitor you while you are taking Apo Flunisolide (Flunisolide-nasal).

Stopping treatment: Treatment with flunisolide should be tapered off gradually as directed by your doctor, not stopped abruptly. Talk with your doctor before stopping Apo Flunisolide (Flunisolide-nasal).

Wound healing: Flunisolide may increase the time it takes for wounds to heal. If you have recently had nasal surgery or trauma, discuss with your doctor how Apo Flunisolide (Flunisolide-nasal) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Flunisolide (Flunisolide-nasal), and whether any special monitoring is needed.

Pregnancy: Apo Flunisolide (Flunisolide-nasal) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Apo Flunisolide (Flunisolide-nasal), contact your doctor immediately.

Breast-feeding: It is not known if flunisolide nasal spray passes into breast milk. If you are a breast-feeding mother and are using Apo Flunisolide (Flunisolide-nasal), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Apo Flunisolide (Flunisolide-nasal) have not been established for children under 6 years of age.