Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who uses Menopur (Gonadotropins-human). If you are concerned about side effects, discuss the risks and benefits of Menopur (Gonadotropins-human) with your doctor.

The following side effects have been reported by at least 1% of people using Menopur (Gonadotropins-human). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal pain
• breast tenderness
• Constipation
• cramps
• dizziness
• feeling of fullness in the abdomen
• flushing
• general feeling of being unwell
• generalized pain (body, back, joint)
• headache
• nausea, vomiting, or Diarrhea (not continuing or severe)
• pain, rash, swelling, or irritation at place of injection
• sweating

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• abnormal vaginal bleeding
• flu-like symptoms (e.g., cough, Fever, sore throat)
• migraine
• mood changes
• pain when urinating
• unusual pain with menstrual bleeding

Stop taking the medication and seek immediate medical attention if any of the following occur:

• difficulty breathing
• signs of a blood clot in blood vessels (e.g., difficulty breathing, chest pain, pain and swelling in one leg muscle)
• signs of Stroke (e.g., sudden trouble with vision, dizziness, sudden severe and unusual headache, weakness, difficulty speaking)
• symptoms of a Anaphylaxis (severe allergic reaction) (e.g., shortness of breath, swelling of the face or throat, or Hives)
• symptoms of ovarian hyperstimulation syndrome or OHSS, e.g.:
  • abdominal or pelvic pain or discomfort
  • bloating
  • diarrhea
  • difficulty breathing
  • decreased amount of urine
  • nausea
  • rapid weight gain
  • vomiting

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Menopur (Gonadotropins-human).

Each sterile vial of lyophilized, white-to-off-white powder or pellet contains 75 IU FSH activity and 75 IU LH activity. Nonmedicinal ingredients: lactose monohydrate, polysorbate 20, sodium phosphate buffer (sodium phosphate dibasic, heptahydrate and phosphoric acid), and sodium chloride injection USP.

Do not use Menopur (Gonadotropins-human) if you:

• are allergic to menotropins or any  ingredients of the medication
• are pregnant
• have high levels of FSH (indicating primary ovarian failure - another reason for infertility)
• have any lesion inside the head such as a pituitary tumour
• have ovarian cysts or enlargement not due to polycystic ovarian syndrome
• have a tumour of the ovaries, fallopian tubes, uterus, vagina, breast, or cervix that is dependent on hormones for growth
• have uncontrolled Thyroid or adrenal gland dysfunction
• have undiagnosed abnormal vaginal bleeding

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Menopur (Gonadotropins-human).

Blood Clots: Menopur (Gonadotropins-human) may increase the chance of blood clot formation, causing a reduction of blood flow to organs or the extremities. If you have a history of clotting, you may be at increased risk of experiencing blood clot-related problems such as Heart Attack, stroke, or clots in the deep veins of your leg. Discuss with your doctor how Menopur (Gonadotropins-human) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Menopur (Gonadotropins-human), and whether any special monitoring is needed.

If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision or difficulty speaking, contact your doctor immediately.

Lung problems: In rare cases, serious lung problems have been reported with the use of menotropins. Get immediate medical attention if you experience difficulty breathing or wheezing.

Multiple births: Multiple births may occur with fertility medications. Talk to your doctor about the risks of multiple births before beginning treatment.

Ovarian enlargement: Some women using Menopur (Gonadotropins-human) may experience ovarian enlargement associated with abdominal bloating or pain. In most cases the bloating and pain stop without treatment within 2 or 3 weeks. If you experience these symptoms contact your doctor.

Ovarian hyperstimulation syndrome (OHSS): Treatment with Menopur (Gonadotropins-human) can cause a condition called ovarian hyperstimulation syndrome (OHSS). It most often develops after treatment has stopped. With OHSS, too many follicles grow and cause abdominal or pelvic discomfort or pain, nausea, vomiting, and weight gain. Some women may experience difficulty breathing, diarrhea, and decreased urination. OHSS can progress rapidly and may become serious. If you experience any of these symptoms while using Menopur (Gonadotropins-human), contact your doctor immediately.

Pregnancy: The effect of menotropins on an unborn baby is not known. To avoid the possibility of harm to the baby, menotropins should not be used during pregnancy.

Breast-feeding: It is not known if menotropins pass into breast milk. If you are a breast-feeding mother and are taking Menopur (Gonadotropins-human), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Menopur (Gonadotropins-human) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for children.

Seniors: Menopur (Gonadotropins-human) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for seniors.