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Mozobil (Plerixafor) belongs to the class of medications called hematopoietic agents. It is used to help collect stem cells for transplantation to treat Non-Hodgkin's Lymphoma and Multiple Myeloma, which are specific cancers affecting blood cells.
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Mozobil (Plerixafor) belongs to the class of medications called hematopoietic agents. It is used to help collect stem cells for transplantation to treat Non-Hodgkin's Lymphoma and Multiple Myeloma, which are specific cancers affecting blood cells. When used along with another medication called granulocyte-colony stimulating factor (G-CSF), Mozobil (Plerixafor) works by increasing the number of blood stem cells in the blood stream so they can be collected and used in stem cell transplant.
Mozobil (Plerixafor) may be available under multiple brand names and/or in several different forms. Any specific brand name of Mozobil (Plerixafor) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Mozobil (Plerixafor) may not be used for all of the conditions discussed here.
Your doctor may have suggested Mozobil (Plerixafor) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Mozobil (Plerixafor), speak to your doctor. Do not stop taking Mozobil (Plerixafor) without consulting your doctor.
Do not give Mozobil (Plerixafor) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Mozobil (Plerixafor) if their doctor has not prescribed it.
Mozobil (Plerixafor) is given by subcutaneous (under the skin) injection, usually in the abdominal area.
The recommended adult dose of Mozobil (Plerixafor) is based on body weight, calculated as 0.24 mg per kilogram of body weight, to a maximum of 40 mg daily. It is usually given as a single dose approximately 10 to 11 hours before the procedure to gather stem cells from the blood.
Mozobil (Plerixafor) is generally given under the supervision of a doctor in a hospital or similar setting with access to sterile equipment for preparation.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Mozobil (Plerixafor) exactly as prescribed by your doctor.
It is important Mozobil (Plerixafor) be given exactly as recommended by your doctor. If you miss an appointment to receive Mozobil (Plerixafor), contact your doctor as soon as possible to reschedule your appointment.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Mozobil (Plerixafor). If you are concerned about side effects, discuss the risks and benefits of Mozobil (Plerixafor) with your doctor.
The following side effects have been reported by at least 1% of people taking Mozobil (Plerixafor). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Mozobil (Plerixafor).
Each 1 mL of sterile, preservative-free, clear, colorless to pale yellow, isotonic solution contains 20 mg of Mozobil (Plerixafor). Nonmedicinal ingredients: sodium chloride in sterile water for injection, adjusted to a pH of 6.0 to 7.5 with hydrochloric acid and sodium hydroxide, if required.
Do not take Mozobil (Plerixafor) if you are allergic to Mozobil (Plerixafor) or any ingredients of the medication.
Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Mozobil (Plerixafor).
Blood counts: Mozobil (Plerixafor) can increase the number of white blood cells and decrease the number of platelets (which help your blood to clot). Your doctor will do blood tests to monitor this. If you notice any signs of infection (e.g., Fever, chills, or sore throat) or unusual bleeding or bruising, contact your doctor immediately.
Blood Pressure: Mozobil (Plerixafor) may cause low blood pressure or dizziness and lightheadedness when rising from a lying or sitting position. People taking medications that can cause dizziness should rise slowly from sitting or lying down to reduce the possibility of severe dizziness or fainting.
Drowsiness/reduced alertness: Mozobil (Plerixafor) may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how Mozobil (Plerixafor) affects you.
Electrolyte balance: Mozobil (Plerixafor) may cause the levels of electrolytes such as potassium, sodium, magnesium, chloride, and calcium in the blood to change while taking Mozobil (Plerixafor). If you experience symptoms of fluid and electrolyte imbalance such as muscle pains or cramps; Dry Mouth; numb hands, feet, or lips; or racing heartbeat, contact your doctor as soon as possible. Your doctor will do blood tests regularly to monitor the levels of these electrolytes in your blood while you are taking Mozobil (Plerixafor).
Heart attack: Although rare, Mozobil (Plerixafor) has been associated with heart attack. If you experience signs of a heart attack such as chest pain or pressure, pain extending through shoulder and arm, nausea and vomiting, sweating, let your doctor know immediately.
Kidney function: Kidney Disease or reduced kidney function may cause Mozobil (Plerixafor) to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how Mozobil (Plerixafor) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Mozobil (Plerixafor), and whether any special monitoring is needed.
Pregnancy: Mozobil (Plerixafor) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Mozobil (Plerixafor), contact your doctor immediately. Women who may become pregnant should use effective birth control while being treated with Mozobil (Plerixafor).
Breast-feeding: It is not known if Mozobil (Plerixafor) passes into breast milk. If you are a breast-feeding mother and are taking Mozobil (Plerixafor), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Mozobil (Plerixafor) have not been established for children.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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