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Ovidrel

Ovidrel

(chorionic-gonadotropin-alfa)

Choriogonadotropin alpha belongs to the class of medications called gonadotropins. Choriogonadotropin alpha, or human chorionic gonadotropin (hCG), is used as part of fertility treatment for women with ovarian dysfunction.

Available form

Dosage

Injectable Syringe

250MCG/0.5ML

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Ovidrel information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The usual dose of choriogonadotropin alpha is 250 µg injected under the skin as directed by your doctor.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Your doctor or other health care professional will show you exactly how to inject the medication. Inspect the solution carefully before injecting it. Do not use your injectable solution if it appears to contain particles or is not clear.

It is important to use Ovidrel (Chorionic-gonadotropin-alfa) exactly as prescribed by your doctor. If you miss a dose of choriogonadotropin alpha, talk to your doctor about when you should receive your next dose.

Store pre-filled syringes at room temperature for up to 30 days or in the refrigerator (2°C to 8°C) until the expiration date. Store pre-filled pens in the refrigerator (2°C to 8°C). Store vials at or below room temperature (25°C). Store in the original package and do not freeze. Protect Ovidrel (Chorionic-gonadotropin-alfa) from light and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Ovidrel (Chorionic-gonadotropin-alfa). If you are concerned about side effects, discuss the risks and benefits of Ovidrel (Chorionic-gonadotropin-alfa) with your doctor.

The following side effects have been reported by at least 1% of people taking Ovidrel (Chorionic-gonadotropin-alfa). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

discomfort, pain, bruising, swelling, or redness at the place of injection
nausea
stomach pain
vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor immediately if any of the following side effects occur:

breast pain
itchy skin

Stop taking the medication and seek immediate medical attention if any of the following occur:

signs of a blood clot in blood vessels (e.g., difficulty breathing, pain and swelling in one leg muscle)
signs of a Anaphylaxis (severe allergic reaction) (e.g., difficulty breathing; Hives; swelling of the mouth, tongue, or throat)
signs of Stroke (e.g., sudden trouble with vision, dizziness, sudden severe and unusual headache, weakness, difficulty speaking)
symptoms of ovarian hyperstimulation syndrome (OHSS), e.g.:
- abdominal or pelvic pain or discomfort
- bloating
- decreased amount of urine
- Diarrhea
- difficulty breathing
- nausea
- rapid weight gain
- vomiting

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Ovidrel (Chorionic-gonadotropin-alfa).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Ovidrel (Chorionic-gonadotropin-alfa).

Blood Clots: Ovidrel (Chorionic-gonadotropin-alfa) may increase the chance of blood clot formation, causing a reduction of blood flow to organs or the extremities.

If you have a history of clotting you may be at increased risk of experiencing blood clot-related problems such as Heart Attack, stroke, pulmonary Embolism (blood clot in the blood vessels of the lungs), or clots in the deep veins of your leg. Discuss with your doctor how Ovidrel (Chorionic-gonadotropin-alfa) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ovidrel (Chorionic-gonadotropin-alfa), and whether any special monitoring is needed.

If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision or difficulty speaking, contact your doctor immediately.

Multiple births: Multiple births may occur with fertility medications. Talk to your doctor about the risks of multiple births before beginning treatment.

Ovarian enlargement: Some women using Ovidrel (Chorionic-gonadotropin-alfa) may experience ovarian enlargement associated with abdominal bloating or pain. In most cases these symptoms go away without treatment within 2 or 3 weeks. If you experience these symptoms contact your doctor.

Ovarian hyperstimulation syndrome (OHSS): Treatment with Ovidrel (Chorionic-gonadotropin-alfa) can cause a condition called ovarian hyperstimulation syndrome (OHSS). With OHSS, too many follicles grow and cause abdominal or pelvic discomfort, pain, nausea, vomiting, and weight gain. Some women may experience difficulty breathing and diarrhea. OHSS can progress rapidly and may become serious. If you experience any of these symptoms, seek immediate medical attention.

Pregnancy: The effect of choriogonadotropin alpha on an unborn baby is not known. To avoid the possibility of harm to the baby, choriogonadotropin alpha should not be used during pregnancy.

Breast-feeding: It is not known if choriogonadotropin alpha passes into breast milk. If you are a breast-feeding mother and are taking Ovidrel (Chorionic-gonadotropin-alfa), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Ovidrel (Chorionic-gonadotropin-alfa) is intended for use by women of child-bearing age and therefore, the safety and effectiveness of Ovidrel (Chorionic-gonadotropin-alfa) have not been established for children.

Seniors: Ovidrel (Chorionic-gonadotropin-alfa) is intended for use by women of child-bearing age and therefore, the safety and effectiveness of Ovidrel (Chorionic-gonadotropin-alfa) have not been established for seniors.

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