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Available Form:   Injectable Syringe
Manufacturer name:   Sanofi-Aventis
Generic name:   alirocumab
Strength:   75mg/1ml

What is Praluent?

Praluent (Alirocumab) is a monoclonal antibody that belongs to the class of medications called proprotein convertase inhibitors (PCSK9 inhibitors). It blocks a protein in the liver, allowing the liver to remove more low-density lipoproteins (LDL or "bad" cholesterol) from the blood.

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Praluent frequently asked questions

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Praluent in Canada?

Shipping cost for Praluent to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Praluent delivered to my home?

You could get Praluent delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Praluent in Canada for free?

You can get Praluent for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Praluent for free.

Praluent How to Take

Praluent (Alirocumab) is a monoclonal antibody that belongs to the class of medications called proprotein convertase inhibitors (PCSK9 inhibitors). It blocks a protein in the liver, allowing the liver to remove more low-density lipoproteins (LDL or "bad" cholesterol) from the blood.

Praluent (Alirocumab) is used in addition to diet and other medications when diet and maximum doses of "statin" cholesterol medication are not enough to lower the LDL levels of people who have High Cholesterol levels. Praluent (Alirocumab) is also used to reduce the risk of Heart Attack, Stroke, and a type of chest pain called unstable Angina for adults who have been diagnosed with cardiovascular disease.

Praluent (Alirocumab) may be available under multiple brand names and/or in several different forms. Any specific brand name of Praluent (Alirocumab) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Praluent (Alirocumab) may not be used for all of the conditions discussed here.

Your doctor may have suggested Praluent (Alirocumab) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Praluent (Alirocumab), speak to your doctor. Do not stop taking Praluent (Alirocumab) without consulting your doctor.

Do not give Praluent (Alirocumab) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Praluent (Alirocumab) if their doctor has not prescribed it.

Discreet Packaging

Your privacy is important. That's why we send your medication inside a plain delivery box so no one will know what's inside.

Praluent Dosage

The recommended starting dose of Praluent (Alirocumab) is 75 mg injected subcutaneously (under the skin) every 2 weeks. Depending on the effectiveness of the medication, your doctor may increase your dose to 150 mg every 2 weeks, but most people find that the lower dose is enough. Alternatively, your doctor may recommend a dose of 300 mg injected once every 4 weeks. This will involve 2 separate injections of 150 mg of Praluent (Alirocumab).

Subcutaneous injections are administered in the abdomen, upper arm, or thigh area. Change the injection site with each injection to keep your skin healthy.

Do not use the injection if it is discoloured or if particles are present.

If you are injecting Praluent (Alirocumab) yourself, your doctor will show you how to use Praluent (Alirocumab) properly. If you are not sure how to use it or have questions about how to use it, contact your doctor. Before using Praluent (Alirocumab), thoroughly read the patient information provided and ask your doctor if you have any questions. If a family member or caregiver will be giving you the injections, your doctor should instruct them on how to give the injection.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Praluent (Alirocumab) exactly as prescribed by your doctor. If you are injecting Praluent (Alirocumab) every 2 weeks and you miss a dose, and it is within 7 days of the missed dose, take it as soon as possible and continue with your regular dosing schedule. If it is more than 7 days since the missed dose, skip the missed dose and continue with your regular dosing schedule. If you are injecting Praluent (Alirocumab) every 4 weeks and it is within 7 days of the missed dose, take it as soon as possible and continue with your regular dosing schedule. If it is more than 7 days since the missed dose, take the missed dose, and start a new schedule from the day you remember to take your dose. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Praluent (Alirocumab) in the refrigerator, protect it from light and moisture, and keep it out of the reach of children. Do not freeze Praluent (Alirocumab). Allow the medication to warm to room temperature for 30 to 40 minutes before you inject it. Once it is removed from the refrigerator, it must be used within 24 hours and must not be put back into the refrigerator.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Praluent Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Praluent (Alirocumab). If you are concerned about side effects, discuss the risks and benefits of Praluent (Alirocumab) with your doctor.

The following side effects have been reported by at least 1% of people taking Praluent (Alirocumab). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • cold-like symptoms (e.g., tiredness, sore throat, nasal congestion)
  • itchiness
  • redness, swelling, pain, or bruising at the injection site

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • Hives
  • rash
  • reddish skin spots, sometimes with blisters

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of hypersensitivity vasculitis (e.g., Diarrhea, rash, purple spots on the skin)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Praluent (Alirocumab).

Free Delivery

Your medication is delivered directly to you at no added cost. We even offer same-day delivery in select locations.

Praluent Available Form

Pre-filled syringe

75 mg/mL
Each 1 mL single-use, pre-filled syringe contains a clear, colourless-to-pale yellow, sterile, preservative-free solution that contains 75 mg of Praluent (Alirocumab). Nonmedicinal ingredients: histidine, sucrose, polysorbate 20, and water for injection (USP), to pH 6.0.

150 mg/mL
Each 1 mL single-use, pre-filled syringe contains a clear, colourless-to-pale yellow, sterile, preservative-free solution that contains 150 mg of Praluent (Alirocumab). Nonmedicinal ingredients: histidine, sucrose, polysorbate 20, and water for injection (USP), to pH 6.0.

Pre-filled pen

75 mg/mL
Each 1 mL single-use, pre-filled pen contains a clear, colourless-to-pale yellow, sterile, preservative-free solution that contains 75 mg of Praluent (Alirocumab). Nonmedicinal ingredients: histidine, sucrose, polysorbate 20, and water for injection (USP), to pH 6.0.

150 mg/mL
Each 1 mL single-use, pre-filled pen contains a clear, colourless-to-pale yellow, sterile, preservative-free solution that contains 150 mg of Praluent (Alirocumab). Nonmedicinal ingredients: histidine, sucrose, polysorbate 20 and water for injection (USP), to pH 6.0.

The rubber needle shield does NOT contain natural latex.

Praluent Contraindications

Do not take Praluent (Alirocumab) if you are allergic to Praluent (Alirocumab) or any ingredients of the medication.

Personalized PocketPacks

We sort your medication into clearly labeled, individual packs so you can be sure you're taking the right dose at the right time.

Praluent Precautions

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Praluent Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Praluent (Alirocumab).

Allergic reactions: As with other monoclonal antibodies, Praluent (Alirocumab) may cause your body to produce antibodies to "defend" your body from the medication. When this happens, an allergic reaction develops. Often, allergic reactions are experienced as a rash, hives or itching. On rare occasions, a Anaphylaxis (severe allergic reaction) may occur, causing difficulty breathing, abdominal cramps, nausea and vomiting, or swelling of the throat (anaphylaxis). Another form of allergic reaction that may occur is hypersensitivity vasculitis, where the blood vessels become inflamed, causing small purplish spots to form on the skin. If you experience any unusual symptoms, contact your doctor.

Pregnancy: Praluent (Alirocumab) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Praluent (Alirocumab), contact your doctor immediately.

Breast-feeding: It is not known if Praluent (Alirocumab) passes into breast milk. If you are a breast-feeding mother and are taking Praluent (Alirocumab), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Praluent (Alirocumab) have not been established for children and adolescents less than 18 years old.

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References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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