Relistor

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Relistor (Methylnaltrexone).

Gastrointestinal perforation: People with advanced illness who use Relistor (Methylnaltrexone) injection may be at increased risk of gastrointestinal perforation (a hole that forms in the wall of the gastrointestinal tract, such as through the stomach or intestines). People are especially at risk if they also have a weakened gastrointestinal wall due to conditions such as cancer, intestinal cancer, or gastrointestinal cancer. If you experience severe, worsening, or persistent abdominal pain that's intensified by movement, nausea and vomiting, or accompanied by Fever or chills, seek immediate medical attention. These could be symptoms of gastrointestinal perforation, which is a medical emergency.

Kidney function: People with severely reduced kidney function require lower doses of Relistor (Methylnaltrexone). If you have Kidney Disease or decreased kidney function, discuss with your doctor how Relistor (Methylnaltrexone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Relistor (Methylnaltrexone), and whether any special monitoring is needed.

Liver function: Relistor (Methylnaltrexone) is not recommended for people who have severely reduced liver function.

Severe diarrhea: Relistor (Methylnaltrexone) may cause severe diarrhea. If you experience this, stop using Relistor (Methylnaltrexone) and contact your doctor as soon as possible.

Pregnancy: Relistor (Methylnaltrexone) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Relistor (Methylnaltrexone), contact your doctor immediately.

Breast-feeding: It is not known if Relistor (Methylnaltrexone) passes into breast milk. If you are a breast-feeding mother and are using Relistor (Methylnaltrexone), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Relistor (Methylnaltrexone) have not been established for children.