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Get your Relistor delivered at your door for FREE
Relistor (Methylnaltrexone) belongs to a group of medications known as opioid receptor antagonists. It is used to treat Constipation caused by prescription pain medications called opioids (e.
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Relistor (Methylnaltrexone) belongs to a group of medications known as opioid receptor antagonists. It is used to treat Constipation caused by prescription pain medications called opioids (e.g., Codeine, Morphine, Hydromorphone) for people who are receiving palliative care. If laxatives are not working, Relistor (Methylnaltrexone) is used along with laxatives to help produce a bowel movement.
It works by preventing opioid medications from binding to certain receptors in the intestinal tract. It does not reduce the pain-relieving effects of opioid pain medications. For most people, Relistor (Methylnaltrexone) usually works within 30 minutes, but it may take longer.
Relistor (Methylnaltrexone) may be available under multiple brand names and/or in several different forms. Any specific brand name of Relistor (Methylnaltrexone) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Relistor (Methylnaltrexone) may not be used for all of the conditions discussed here.
Your doctor may have suggested Relistor (Methylnaltrexone) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given Relistor (Methylnaltrexone), speak to your doctor. Do not stop using Relistor (Methylnaltrexone) without consulting your doctor.
Do not give Relistor (Methylnaltrexone) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use Relistor (Methylnaltrexone) if their doctor has not prescribed it.
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The usual recommended dose of Relistor (Methylnaltrexone) is based on body weight:
For people who weigh less than 33 kg or more than 126 kg, your doctor will calculate the dose of Relistor (Methylnaltrexone) that is appropriate for you.
Relistor (Methylnaltrexone) is injected once every other day under the skin of the upper arm, abdomen, or thigh.
It is important to use Relistor (Methylnaltrexone) exactly as prescribed by your doctor. If you (or a family member or friend) are injecting Relistor (Methylnaltrexone), a health care professional will show you how to inject the medication properly. Read the instructions provided in the package insert carefully. If you are not sure how to use Relistor (Methylnaltrexone), contact your doctor or pharmacist.
It is recommended that you use a different site for each injection. Do not inject into skin that is tender, red, bruised, hard, or has stretch marks or scars. If you are giving the injection to yourself, do not inject into the upper arm. You should be sitting or lying down when you receive Relistor (Methylnaltrexone). Do not stand up quickly after the injection as you may feel dizzy.
If you do not notice improvement within a week, contact your doctor.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
Store Relistor (Methylnaltrexone) at room temperature, protect it from light, and keep it out of the reach of children. Do not allow it to freeze.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Relistor (Methylnaltrexone). If you are concerned about side effects, discuss the risks and benefits of Relistor (Methylnaltrexone) with your doctor.
The following side effects have been reported by at least 1% of people taking Relistor (Methylnaltrexone). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Relistor (Methylnaltrexone).
We manage your refills and get in touch with your doctors for prescription renewals so that you always have the medication you need.
Each mL of sterile, clear and colourless to pale yellow aqueous solution for injection contains Relistor (Methylnaltrexone) bromide 20 mg. Each vial contains 12 mg of Relistor (Methylnaltrexone) bromide in 0.6 mL of sterile water for injection. Nonmedicinal ingredients: edetate calcium disodium, glycine hydrochloride, sodium chloride, and sterile water for injection. The solution is isotonic and the pH is adjusted during manufacture with hydrochloric acid and/or sodium hydroxide to approximately 3.4.
Do not use Relistor (Methylnaltrexone) if you:
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There may be an interaction between Relistor (Methylnaltrexone) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Relistor (Methylnaltrexone). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Relistor (Methylnaltrexone).
Gastrointestinal perforation: People with advanced illness who use Relistor (Methylnaltrexone) injection may be at increased risk of gastrointestinal perforation (a hole that forms in the wall of the gastrointestinal tract, such as through the stomach or intestines). People are especially at risk if they also have a weakened gastrointestinal wall due to conditions such as cancer, intestinal cancer, or gastrointestinal cancer. If you experience severe, worsening, or persistent abdominal pain that's intensified by movement, nausea and vomiting, or accompanied by Fever or chills, seek immediate medical attention. These could be symptoms of gastrointestinal perforation, which is a medical emergency.
Kidney function: People with severely reduced kidney function require lower doses of Relistor (Methylnaltrexone). If you have Kidney Disease or decreased kidney function, discuss with your doctor how Relistor (Methylnaltrexone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Relistor (Methylnaltrexone), and whether any special monitoring is needed.
Liver function: Relistor (Methylnaltrexone) is not recommended for people who have severely reduced liver function.
Severe diarrhea: Relistor (Methylnaltrexone) may cause severe diarrhea. If you experience this, stop using Relistor (Methylnaltrexone) and contact your doctor as soon as possible.
Pregnancy: Relistor (Methylnaltrexone) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Relistor (Methylnaltrexone), contact your doctor immediately.
Breast-feeding: It is not known if Relistor (Methylnaltrexone) passes into breast milk. If you are a breast-feeding mother and are using Relistor (Methylnaltrexone), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Relistor (Methylnaltrexone) have not been established for children.
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All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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