Repronex

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Repronex (Gonadotropins-human). If you are concerned about side effects, discuss the risks and benefits of Repronex (Gonadotropins-human) with your doctor.

The following side effects have been reported by at least 1% of people taking Repronex (Gonadotropins-human). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• bloating
• breast tenderness
• Diarrhea
• dizziness
• flushing
• headache
• nausea
• pain, rash, swelling, or irritation at place of injection or elsewhere on the body
• stomach cramping

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• abdominal or pelvic pain, bloating, cramping, or discomfort (temporary)
• abnormal vaginal bleeding

Stop taking the medication and seek immediate medical attention if any of the following occur:

• difficulty breathing
• signs of a blood clot in blood vessels (e.g., difficulty breathing, chest pain, pain and swelling in one leg muscle)
• signs of Stroke (e.g., sudden trouble with vision, dizziness, sudden severe and unusual headache, weakness, difficulty speaking)
• symptoms of a Anaphylaxis (severe allergic reaction) (e.g., itchy body rash; difficulty breathing; or swelling of the face, mouth, throat, or tongue)
• symptoms of ovarian hyperstimulation syndrome (OHHS; e.g., abdominal or pelvic pain, discomfort, or bloating, nausea, vomiting, diarrhea, difficulty breathing, decreased urination, weight gain)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Repronex (Gonadotropins-human).

Each vial of sterile, white-to-off-white powder contains 75 IU FSH and 75 IU LH. Nonmedicinal ingredients: lactose monohydrate and sodium chloride injection.

Do not use Repronex (Gonadotropins-human) if you:

• are allergic to menotropins or any ingredients of Repronex (Gonadotropins-human)
• are pregnant
• have any lesion inside the head, such as a pituitary tumour
• have high levels of FSH (indicating another reason for infertility)
• have infertility that is not caused by the lack of ovulation (unless the medication is being used for in-vitro fertilization)
• have ovarian cysts or enlargement that is not caused by Polycystic Ovary Syndrome
• have uncontrolled Thyroid and adrenal gland dysfunction
• have undiagnosed abnormal vaginal bleeding

Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Repronex (Gonadotropins-human).

Blood Clots: Repronex (Gonadotropins-human) may increase the chance of blood clot formation, causing reduction of blood flow to organs or the extremities.

If you experience symptoms such as sharp pain and swelling in the leg, difficulty breathing, chest pain, blurred vision or difficulty speaking, contact your doctor immediately.

Lung problems: In rare cases, lung problems have been reported with the use of Repronex (Gonadotropins-human). If you experience difficulty breathing, shortness of breath, or tiring easily with mild exertion, contact your doctor. If you have breathing problems, talk to your doctor about the risks and benefits of using Repronex (Gonadotropins-human).

Multiple births: Repronex (Gonadotropins-human) may increase the risk of multiple births (e.g., twins). Talk to your doctor about the risks of multiple births before beginning treatment.

Ovarian enlargement: Some women using Repronex (Gonadotropins-human) may experience ovarian enlargement associated with abdominal bloating or pain. In most cases, the pain and bloating will stop without treatment within 2 or 3 weeks. If you experience these symptoms, contact your doctor.

Ovarian hyperstimulation syndrome (OHSS): Treatment with Repronex (Gonadotropins-human) can cause a condition called ovarian hyperstimulation syndrome (OHHS). It most often develops after treatment has stopped. With OHHS, too many follicles grow and cause abdominal or pelvic discomfort or pain, nausea, vomiting, and weight gain. Some women may experience difficulty breathing and diarrhea. OHHS can progress rapidly and may become serious. If you experience any of these symptoms, contact your doctor immediately.

Pregnancy: Repronex (Gonadotropins-human) should not be used during pregnancy.

Breast-feeding: It is not known if menotropins pass into breast milk. If you are a breast-feeding mother and are taking Repronex (Gonadotropins-human), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Repronex (Gonadotropins-human) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for children.

Seniors: Repronex (Gonadotropins-human) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for seniors.