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Ursodiol is used to treat a group of conditions known as cholestatic liver diseases (e. g.
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Ursodiol is used to treat a group of conditions known as cholestatic liver diseases (e.g., primary biliary cirrhosis). Cholestatic liver diseases are characterized by a decrease in bile secretion and bile flow.
Ursodiol is a natural component of bile and helps to increase the amount of bile and to increase bile flow. This helps symptoms associated with cholestatic liver diseases.
Ursodiol may be available under multiple brand names and/or in several different forms. Any specific brand name of Ursodiol may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Ursodiol may not be used for all of the conditions discussed here.
Your doctor may have suggested Ursodiol for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Ursodiol, speak to your doctor. Do not stop taking Ursodiol without consulting your doctor.
Do not give Ursodiol to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Ursodiol if their doctor has not prescribed it.
To treat cholestatic liver diseases, the recommended adult dose of ursodiol is based on body weight. Your doctor will calculate a dose of 13 mg to 15 mg per kilogram of body weight per day, taken by mouth in 2 to 4 divided doses.
Ursodiol should be taken with food.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that Ursodiol be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store the medication at room temperature, protect from light and moisture, and keep it out of reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Ursodiol.If you are concerned about side effects, discuss the risks and benefits of Ursodiol with your doctor.
The following side effects have been reported by at least 1% of people taking Ursodiol. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Ursodiol.
Each white-to-off-white, oval, film-coated tablet debossed with “G72” on one side and “250” on the other contains 250 mg of urosdiol. Nonmedicinal ingredients: carnauba wax, dibutyl sebacate, cetyl alcohol, ethylcellulose, sodium lauryl sulfate, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, Polyethylene Glycol 3350, polyethylene glycol 8000, povidone, and sodium starch glycolate.
Each white-to-off-white, oval, film-coated tablet, plain with score line on one side and debossed with "U11" on the other, contains 500 mg of ursodiol. Nonmedicinal ingredients: carnauba wax, dibutyl sebacate, cetyl alcohol, ethylcellulose, sodium lauryl sulfate, hydroxypropyl methylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol 3350, polyethylene glycol 8000, povidone, and sodium starch glycolate.
Do not take Ursodiol if you:
There may be an interaction between ursodiol and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Ursodiol. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Ursodiol.
Liver disease: Ursodiol is broken down by the liver. Liver disease or reduced liver function may cause Ursodiol to build up in the body, causing side effects and possibly worsen liver damage. If you have liver disease, discuss with your doctor how Ursodiol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ursodiol, and whether any special monitoring is needed.
Monitoring: Your doctor should order monthly liver function tests for the first 3 months you are taking Ursodiol, and every 6 months after that. Improvements in the results of these blood tests do not always mean that the disease is improving. Do not stop taking Ursodiol without talking to your doctor.
Pregnancy: Ursodiol should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Ursodiol, contact your doctor immediately.
Breast-feeding: It is not known if ursodiol passes into breast milk. If you are a breast-feeding mother and are taking Ursodiol, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Ursodiol have not been established for children.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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