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Botulinum toxin belongs to the class of medications called neuromuscular paralytic agents. It blocks the nerves that are responsible for muscle activity.
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Botulinum toxin belongs to the class of medications called neuromuscular paralytic agents. It blocks the nerves that are responsible for muscle activity. For cosmetic purposes, it can be used to smooth out facial lines and wrinkles, such as those that form between the eyebrows, on the forehead, and around the eyes (crow's feet). It gives skin a smoother appearance by relaxing the muscles in the area where it was injected.
Botox Cosmetic (Onabotulinumtoxin-a) may be available under multiple brand names and/or in several different forms. Any specific brand name of Botox Cosmetic (Onabotulinumtoxin-a) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Botox Cosmetic (Onabotulinumtoxin-a) may not be used for all of the conditions discussed here.
Your doctor may have suggested Botox Cosmetic (Onabotulinumtoxin-a) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are receiving Botox Cosmetic (Onabotulinumtoxin-a), speak to your doctor. Do not stop receiving Botox Cosmetic (Onabotulinumtoxin-a) without consulting your doctor.
The dose of medication required depends on the area being treated and individual circumstances.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are receiving the medication without consulting your doctor.
Botulinum toxin is available in injectable form. The injection will be given into a muscle by a qualified health care professional.
It is important to receive Botox Cosmetic (Onabotulinumtoxin-a) exactly as recommended by your doctor. If you miss an appointment to receive botulinum toxin type A (purified neurotoxin complex), contact your doctor as soon as possible to reschedule your appointment. It is very important to keep your appointments for treatment and follow-up.
Before mixing, Botox Cosmetic (Onabotulinumtoxin-a) is stored in the refrigerator or freezer. Once mixed, it can be stored for up to 24 hours in the refrigerator.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Botox Cosmetic (Onabotulinumtoxin-a). If you are concerned about side effects, discuss the risks and benefits of Botox Cosmetic (Onabotulinumtoxin-a) with your doctor.
The following side effects have been reported by at least 1% of people taking Botox Cosmetic (Onabotulinumtoxin-a). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Botox Cosmetic (Onabotulinumtoxin-a).
Each sterile vial contains 50, 100, or 200 Allergan units of vacuum-dried Clostridium botulinum toxin type A. Nonmedicinal ingredients: human serum Albumin and sodium chloride. No preservatives.
Botulinum toxin type A (cosmetic) should not be used by anyone who:
There may be an interaction between botulinum toxin type A (purified neurotoxin complex) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Botox Cosmetic (Onabotulinumtoxin-a). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Botox Cosmetic (Onabotulinumtoxin-a).
Health Canada has issued new restrictions concerning the use of Botox Cosmetic (botulinum toxin type A). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Distant toxin spread: Very rarely, Botox Cosmetic (Onabotulinumtoxin-a) may spread to other parts of the body other than where it was injected, leading to muscle weakness, difficulty swallowing, pneumonia, speech difficulties, and breathing problems. Distant toxin spread can be fatal. If you develop severe difficulty swallowing, speaking, or breathing while using Botox Cosmetic (Onabotulinumtoxin-a), contact your doctor immediately.
Other medical conditions: People with amyotrophic lateral sclerosis, with disorders that produce a depletion of acetylcholine, or disorders that produce peripheral neuromuscular dysfunction should discuss with their doctor how Botox Cosmetic (Onabotulinumtoxin-a) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Botox Cosmetic (Onabotulinumtoxin-a), and whether any special monitoring is needed.
Pregnancy: Botox Cosmetic (Onabotulinumtoxin-a) is not recommended during pregnancy. If you become pregnant while using Botox Cosmetic (Onabotulinumtoxin-a), contact your doctor immediately.
Breast-feeding: It is not known if Botox Cosmetic (Onabotulinumtoxin-a) passes into breast milk. If you are a breast-feeding mother and are using Botox Cosmetic (Onabotulinumtoxin-a), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Botox Cosmetic (Onabotulinumtoxin-a) is not recommended for children.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
December 18, 2023
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