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Available Form:   Injectable Powder
Manufacturer name:   Pfizer
Generic name:   alprostadil-urogenital
Strength:   20mcg

What is Caverject?

Alprostadil belongs to a class of medications known as prostaglandins. Prostaglandins like alprostadil cause increased blood flow to certain areas of the body by causing the blood vessels in the area to widen.

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Caverject frequently asked questions

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Caverject in Canada?

Shipping cost for Caverject to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Caverject delivered to my home?

You could get Caverject delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Caverject in Canada for free?

You can get Caverject for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Caverject for free.

Caverject How to Take

Alprostadil belongs to a class of medications known as prostaglandins. Prostaglandins like alprostadil cause increased blood flow to certain areas of the body by causing the blood vessels in the area to widen.

In particular, an alprostadil injection causes increased blood flow to the penis. It allows more blood to flow into the penis and helps to produce an erection. Alprostadil is used to treat Erectile Dysfunction (also known as male impotence). The goal is to achieve erections that last up to one hour.

Caverject (Alprostadil-urogenital) may be available under multiple brand names and/or in several different forms. Any specific brand name of Caverject (Alprostadil-urogenital) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Caverject (Alprostadil-urogenital) may not be used for all of the conditions discussed here.

Your doctor may have suggested Caverject (Alprostadil-urogenital) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given Caverject (Alprostadil-urogenital), speak to your doctor. Do not stop using Caverject (Alprostadil-urogenital) without consulting your doctor.

Do not give Caverject (Alprostadil-urogenital) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use this medication if their doctor has not prescribed it.

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Caverject Dosage

Alprostadil is given by injection into the blood-filled spaces of the penis. Your doctor will determine the appropriate dose of alprostadil by assessing the nature of the impotence. Your doctor will give an initial injection and then slowly increase the dose over the course of the next injections until the lowest dose for an effective erection is found. Erection should occur within 5 to 20 minutes after injection.

The initial dose of alprostadil is usually around 1.25 µg to 2.5 µg (depending on the cause of the erectile dysfunction). The amount of medication will be increased until the lowest effective dose is reached. The maximum daily dose should not exceed 60 µg. Alprostadil should be used no more than once a day and no more than 3 times a week, with at least 24 hours between each dose.

If the erection lasts for 2 hours, try to reduce the erection by methods suggested by the doctor. A prolonged erection (3 hours or more) should be reported to the doctor immediately.

Do not inject alprostadil into an erect penis. Never increase or decrease the dose without consulting your doctor. Once the correct dose has been found, the first few injections will take place at your doctor's office so you can learn how to inject the medication properly. Once your doctor is assured that you are comfortable with the procedure, you will be given a prescription for a kit to use at home.

Refer to the package insert for details on how to mix the medication and inject it properly. Everything you need to use the medication comes with the kit. It is important to visit your doctor regularly, at least once every 3 months during treatment, to ensure that the medication is working safely and effectively.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use Caverject (Alprostadil-urogenital) exactly as prescribed by your doctor.

Store unused vials of Caverject (Alprostadil-urogenital) between 2°C and 30°C and do not let it freeze. Keep it out of the reach of children. Once mixed, the solution must be used immediately. Each vial is intended for a single use only. Safely discard any remaining solution after using the injection. Do not reuse or share needles.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Caverject Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Caverject (Alprostadil-urogenital). If you are concerned about side effects, discuss the risks and benefits of Caverject (Alprostadil-urogenital) with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • blood blisters at the injection site
  • bruising or clotted blood in penis at site of injection (if injected incorrectly)
  • burning sensation or tension in the penis
  • discomfort or irritation
  • dizziness
  • feeling faint
  • headache
  • pain and/or swelling at site of injection
  • painful erection (usually mild-to-moderate intensity)
  • prolonged erection
  • short-term bleeding at site of injection
  • skin rash or redness

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abnormal ejaculation
  • curving of penis with pain during erection
  • nodules or hard tissue appearing in the penis
  • inflammation of the tip of the penis
  • pain in the testicles or at the base of the penis

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • broken needle that cannot be removed
  • prolonged erection (erections that last for 3 hours or more)
  • changes in blood pressure
  • fast or irregular heart beat

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Caverject (Alprostadil-urogenital).

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Caverject Available Form

20 µg/vial kit
Each case contains a single-dose vial of alprostadil 20 µg sterile powder, 1 mL prefilled syringe of BWFI (bacteriostatic water for injection) diluent, a 27-gauge 0.5 inch needle, 2 alcohol swabs, and a patient administration leaflet. These cases are fitted with a lock designed for safe and convenient disposal of the contents after use. Once reconstituted, each mL contains alprostadil 20 µg, lactose monohydrate 172 mg, sodium citrate dihydrate 47 µg, benzyl alcohol 8.4 mg, and sterile water for injection qs.

Caverject Contraindications

Do not use alprostadil (Caverject®) if you:

  • are allergic to alprostadil (Caverject®) or any ingredients of the medication
  • are a man for whom sexual activity is inadvisable
  • have conditions that increase the risk of priapism, such as sickle cell Anemia, Multiple Myeloma, or Leukemia
  • have deformations of the penis, such as angulation, fibrosis, or Peyronie's disease
  • have penile implants

Do not use Caverject (Alprostadil-urogenital) if you are female or less than 18 years of age.

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Caverject Precautions

There may be an interaction between alprostadil (Caverject®) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Caverject Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Blood-borne diseases: The injection of alprostadil may cause a small amount of bleeding at the injection site. For those with a blood-borne disease, this may increase the risk of transferring the disease between sexual partners.

Prolonged erection: If the erection lasts for 2 hours, try to reduce the erection by methods suggested by your doctor. A prolonged erection (3 hours or more) or priapism (a painful erection lasting longer than 6 hours) should be reported to your doctor immediately.

Sexually transmitted infections (STIs): This medication does not reduce the risk of passing HIV or other sexually transmitted infections to others through sexual contact or blood contamination. It is recommended that latex condoms be used in combination with Caverject (Alprostadil-urogenital) to protect against these infections.

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All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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