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This combination medication contains two active ingredients: atovaquone and proguanil. It is used to treat and prevent Malaria.
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This combination medication contains two active ingredients: atovaquone and proguanil. It is used to treat and prevent Malaria. It works by killing P. falciparum, the parasite that causes malaria. It may be effective in areas where other antimalarial medications are no longer effective.
Teva Atovaquone Proguanil may be available under multiple brand names and/or in several different forms. Any specific brand name of Teva Atovaquone Proguanil may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Teva Atovaquone Proguanil may not be used for all of the conditions discussed here.
Your doctor may have suggested Teva Atovaquone Proguanil for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Teva Atovaquone Proguanil, speak to your doctor. Do not stop taking Teva Atovaquone Proguanil without consulting your doctor.
Do not give Teva Atovaquone Proguanil to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Teva Atovaquone Proguanil if their doctor has not prescribed it.
The usual recommended adult dose for preventing malaria is 1 tablet daily, starting 1 to 2 days before entering an area where malaria is present and continuing until 7 days after leaving the affected area.
The usual recommended adult dose for treating malaria is 4 tablets once daily for 3 days.
Children's doses for malaria prevention and treatment are based on body weight.
Teva Atovaquone Proguanil should be swallowed whole with fluid; however, it may be crushed and mixed in condensed milk immediately before taking the dose if it cannot be swallowed whole.
Teva Atovaquone Proguanil should be taken with food or a milky drink at the same time each day. If vomiting occurs within one hour of the dose, another dose should be taken. If vomiting continues, your doctor will likely consider using another treatment.
People who are unable to eat food should use a different treatment if possible, as the absorption of the medication is significantly reduced when the stomach is empty.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Teva Atovaquone Proguanil exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Teva Atovaquone Proguanil at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Teva Atovaquone Proguanil. If you are concerned about side effects, discuss the risks and benefits of Teva Atovaquone Proguanil with your doctor.
The following side effects have been reported by at least 1% of people taking Teva Atovaquone Proguanil. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Teva Atovaquone Proguanil.
Each pink, round, biconvex, bevelled-edge, film-coated tablet, debossed with "77" and "227" on one side, contains 250 mg of atovaquone and 100 mg proguanil hydrochloride (equivalent to 87.4 mg proguanil base). Nonmedicinal ingredients: low-substituted hydroxypropyl cellulose, magnesium stearate, microcrystalline cellulose, poloxamer 188, povidone K30, and sodium starch glycolate. Tablet coating: hydroxypropylmethylcellulose 2910, polyethylene glycol 8000, polyethylene glycol 400, titanium dioxide, and ferric oxide red.
Do not take Teva Atovaquone Proguanil if you:
There may be an interaction between atovaquone - proguanil and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Teva Atovaquone Proguanil. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Teva Atovaquone Proguanil.
Depression and mental illness: People taking Teva Atovaquone Proguanil may feel agitated (restless, anxious, aggressive, emotional, and feeling not like themselves), or they may want to hurt themselves or others. These symptoms may occur within several weeks after starting Teva Atovaquone Proguanil. If you experience these side effects or notice them in a family member who is taking Teva Atovaquone Proguanil, contact your doctor immediately.
If you have a history of mental illness or depression, discuss with your doctor how Teva Atovaquone Proguanil may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Atovaquone Proguanil, and whether any special monitoring is needed.
Dizziness: Teva Atovaquone Proguanil may cause dizziness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you have determined how Teva Atovaquone Proguanil affects you.
Epilepsy: Rarely, seizures have been reported by people taking Teva Atovaquone Proguanil. If you have epilepsy or a history of seizure disorder, discuss with your doctor how Teva Atovaquone Proguanil may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Atovaquone Proguanil, and whether any special monitoring is needed.
Kidney function: Kidney Disease or reduced kidney function may cause Teva Atovaquone Proguanil to build up in the body, causing side effects. If you have kidney problems, discuss with your doctor how Teva Atovaquone Proguanil may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Atovaquone Proguanil, and whether any special monitoring is needed. Teva Atovaquone Proguanil is not recommended for people with severe kidney impairment.
Pregnancy: Teva Atovaquone Proguanil should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Teva Atovaquone Proguanil, contact your doctor immediately.
Breast-feeding: It is not known if atovaquone passes into breast milk. Proguanil passes into breast milk. If you are a breast-feeding mother and are taking atovaquone - proguanil, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Atovaquone - proguanil may be used for treating malaria in children who are at least 3 years old and weigh at least 11 kilograms. Atovaquone - proguanil may be used for preventing malaria in children who weigh at least 11 kilograms. The safety and effectiveness of using Teva Atovaquone Proguanil for children smaller than this have not been determined and should be avoided.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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