Metonia (Metoclopramide) belongs to the classes of medications called antiemetics and prokinetics. It is used to improve stomach emptying after surgery or other procedures. It can also be used to prevent nausea after operations and is useful in preventing the nausea and vomiting associated with cancer chemotherapy. It works by speeding up the rate at which the stomach empties and by blocking nausea triggers in the brain.

Metonia (Metoclopramide) may be available under multiple brand names and/or in several different forms. Any specific brand name of Metonia (Metoclopramide) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Metonia (Metoclopramide) may not be used for all of the conditions discussed here.

Your doctor may have suggested Metonia (Metoclopramide) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Metonia (Metoclopramide), speak to your doctor. Do not stop taking Metonia (Metoclopramide) without consulting your doctor.

Do not give Metonia (Metoclopramide) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Metonia (Metoclopramide) if their doctor has not prescribed it.

The recommended adult dose of Metonia (Metoclopramide) for symptoms resulting from delayed stomach emptying ranges from 5 mg to 10 mg 3 or 4 times daily before meals. The recommended dose for children (aged 5 to 14 years) is 2.5 mg to 5 mg 3 times daily before meals. The injectable form of Metonia (Metoclopramide) is most often used for the prevention of nausea and vomiting caused by chemotherapy. It is usually given by a health care professional in a hospital. The maximum daily dose for both adults and children is 0.5 mg/kg of body weight. 

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Metonia (Metoclopramide) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Metonia (Metoclopramide) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Metonia (Metoclopramide). If you are concerned about side effects, discuss the risks and benefits of Metonia (Metoclopramide) with your doctor.

The following side effects have been reported by at least 1% of people taking Metonia (Metoclopramide). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• Diarrhea (with high doses)
• difficulty sleeping
• dizziness
• drowsiness
• fatigue
• headache
• restlessness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• difficulty speaking or swallowing
• dizziness or fainting
• fast or irregular heartbeat
• Fever
• general feeling of tiredness or weakness
• headache (severe or continuing)
• inability to move eyes
• increase in blood pressure
• lip smacking or puckering
• loss of balance control
• mask-like face
• muscle spasms of face, neck, and back
• puffing of cheeks
• rapid or worm-like movements of tongue
• shuffling walk
• signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
• sore throat
• stiffness of arms or legs
• tic-like or twitching movements
• trembling and shaking of hands and fingers
• twisting movements of body
• uncontrolled chewing movements
• uncontrolled movements of arms and legs
• unusual eye movements
• weakness of arms and legs

Stop taking the medication and seek immediate medical attention if any of the following occur:

• signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Metonia (Metoclopramide).

Tablet

5 mg
Each white, square, biconvex tablet, debossed "P" on one side and "M" over "5" on the other side, contains 5 mg of Metonia (Metoclopramide) hydrochloride. Nonmedicinal ingredients: colloidal silicon dioxide, lactose, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

10 mg
Each white, round, biconvex tablet, debossed "P" on one side and "M" scoreline "10" on the other side, contains 10 mg of Metonia (Metoclopramide) hydrochloride. Nonmedicinal ingredients: colloidal silicon dioxide, lactose, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

Liquid

Do not take Metonia (Metoclopramide) if you:

• are allergic to Metonia (Metoclopramide) or any of the ingredients of this medication
• have a condition where faster passage of materials through the stomach might be dangerous (e.g., in cases of stomach bleeding, or breaks in the stomach lining)

Metonia (Metoclopramide) should not be given to children less than one year of age.

There may be an interaction between Metonia (Metoclopramide) and any of the following:

• aclidinium
• antihistamines (e.g., cetirizine, doxylamine, Diphenhydramine, Hydroxyzine, Loratadine)
• anti-Parkinson's medications (e.g., amantadine, Apomorphine, Bromocriptine, levodopa, Pramipexole, Ropinirole, Rotigotine)
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
• atovaquone
• atropine
• azelastine
• "azole" antifungals (e.g., fluconazole, itraconazole, ketoconazole, Voriconazole)
• belladonna
• Benztropine
• bromocriptine
• Bupropion
• Buspirone
• Cyclobenzaprine
• Cyclosporine
• Darifenacin
• Dextromethorphan
• Disopyramide
• ergot alkaloids (e.g., ergotamine, Dihydroergotamine)
• Fesoterodine
• Flavoxate
• glycopyrrolate
• ipratropium
• ketotifen
• lithium
• macrolide antibiotics (e.g., clarithromycin, erythromycin)
• Mirtazapine
• monoamine oxidase inhibitors (M.O.S. e.g., Moclobemide, Phenelzine, Rasagiline, Selegiline, Tranylcypromine)
• narcotic pain relievers (e.g., Codeine, Fentanyl, Morphine, Oxycodone)
• orphenadrine
• Oxybutynin
• Prochlorperazine
• quinidine
• quinine
• Rivastigmine
• ropinirole
• scopolamine
• selective serotonin reuptake inhibitors (SSRI; e.g., Fluoxetine, Paroxetine, Sertraline)
• serotonin/norepinephrine reuptake inhibitors (SNRIs; e.g., Desvenlafaxine, Duloxetine, Venlafaxine)
• St. John's wort
• Solifenacin
• Tacrolimus
• Tapentadol
• Tetrabenazine
• tipranavir
• tiotropium
• Tolterodine
• Tramadol
• Trazodone
• tricyclic antidepressants (e.g., Amitriptyline, Desipramine, Nortriptyline)
• "triptan" migraine medications (e.g., Eletriptan, Sumatriptan)
• Tryptophan
• umeclidinium

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Metonia (Metoclopramide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.