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What is Starlix?

Starlix (Nateglinide) belongs to the group of medications known as oral hypoglycemics or oral antidiabetic agents. Starlix (Nateglinide) is used to control blood glucose for people with Type 2 Diabetes.

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Starlix (Nateglinide) belongs to the group of medications known as oral hypoglycemics or oral antidiabetic agents. Starlix (Nateglinide) is used to control blood glucose for people with Type 2 Diabetes.

In combination with exercise and a healthy diet, Starlix (Nateglinide) works to control blood glucose by increasing the amount of insulin released from the pancreas. It is used when diet, exercise, and weight reduction have not been found to control blood glucose well enough on their own. Starlix (Nateglinide) can be used on its own or in combination with another antidiabetic medication, Metformin.

Your doctor may have suggested Starlix (Nateglinide) for conditions other than the ones listed in these drug information articles. As well, some forms of Starlix (Nateglinide) may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Starlix (Nateglinide), speak to your doctor. Do not stop taking Starlix (Nateglinide) without consulting your doctor.

Do not give Starlix (Nateglinide) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Starlix (Nateglinide) if their doctor has not prescribed it.



The usual dose of Starlix (Nateglinide) is 120 mg, taken before meals. It is usually taken immediately before each meal, but may be taken up to 30 minutes before each meal. The dosage may be adjusted depending on your response to the medication and whether you reach your target blood sugar levels.

If a meal is skipped, the dose usually taken with that meal should not be taken.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.

It is important to use Starlix (Nateglinide) exactly as prescribed by the doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Starlix (Nateglinide) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Starlix (Nateglinide). If you are concerned about side effects, discuss the risks and benefits of Starlix (Nateglinide) with your doctor.

The following side effects have been reported by at least 1% of people taking Starlix (Nateglinide). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abdominal or stomach pain
  • back pain
  • chills
  • cough
  • dizziness
  • heartburn
  • pain in the joints or muscles
  • runny or stuffy nose
  • sneezing
  • sore throat
  • swelling in the joints

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • symptoms of low blood glucose, including:
    • anxious feelings
    • behaviour changes similar to being drunk
    • blurred vision
    • cold sweats
    • confusion
    • cool, pale skin
    • difficulty thinking
    • drowsiness
    • excessive hunger
    • fast heartbeat
    • headache
    • nausea
    • nervousness
    • nightmares
    • restless sleep
    • shakiness
    • slurred speech
    • unusual tiredness or weakness

Stop taking the medication and seek immediate medical attention if any of the following occur:

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Starlix (Nateglinide).


Available form

July 13, 2015

Starlix (Nateglinide) is no longer being manufactured for sale in Canada. This article is being kept available for reference purposes only. If you are using Starlix (Nateglinide), speak with your doctor or pharmacist for information about your treatment options.



Do not take this mediction if you:

  • are allergic to Starlix (Nateglinide) or to any of the ingredients of the medication
  • are pregnant
  • have diabetic ketoacidosis
  • have Type 1 Diabetes



There may be an interaction between Starlix (Nateglinide) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Starlix (Nateglinide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.



Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Starlix (Nateglinide).

Liver disease: If you have moderate-to-severe liver disease, discuss with your doctor how Starlix (Nateglinide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Starlix (Nateglinide), and whether any special monitoring is needed.

Low blood glucose: Starlix (Nateglinide) may cause low blood glucose (Hypoglycemia). Certain people are more sensitive to this effect, including seniors, people who are undernourished, and people who have exercised more strenuously than usual. If you are taking other diabetes medications, have consumed alcohol, or have other medical conditions that cause low blood glucose (e.g., an underactive pituitary or adrenal gland, or kidney problems), you may need to check your blood glucose levels more frequently. Consult your doctor for advice about whether any special monitoring is necessary.

Pregnancy: Starlix (Nateglinide) should not be used during pregnancy. If you think you may be pregnant or if you become pregnant while taking Starlix (Nateglinide), contact your doctor immediately.

Breast-feeding: It is not known if Starlix (Nateglinide) passes into breast milk. If you are a breast-feeding mother and are taking Starlix (Nateglinide), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Starlix (Nateglinide) have not been established for children.

Starlix frequently asked questions

How To Buy Starlix Online?

You can buy Starlix online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Starlix?

You can consult a Canadian doctor online at Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Starlix in Canada?

Shipping cost for Starlix to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

How to get Starlix delivered to my home?

You could get Starlix delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Starlix in Canada for free?

You can get Starlix for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Starlix for free.

Can I consult a doctor online to get Starlix?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Starlix.

Can I buy Starlix without a prescription?

You need a valid prescription to buy Starlix from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.


All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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