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What is Levothyroxine?

Levothyroxine is a Thyroid hormone supplement used to treat people who do not produce enough thyroid hormone on their own. Levothyroxine helps to reduce the symptoms of low thyroid hormone such as weight gain, sensitivity to cold, lack of energy, and dry skin.

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Levothyroxine is a Thyroid hormone supplement used to treat people who do not produce enough thyroid hormone on their own. Levothyroxine helps to reduce the symptoms of low thyroid hormone such as weight gain, sensitivity to cold, lack of energy, and dry skin. It may take several weeks for Levothyroxine to have a noticeable effect on your condition.

Levothyroxine is also used to decrease the size of an enlarged thyroid gland, also known as goiter.

Levothyroxine may be available under multiple brand names and/or in several different forms. Any specific brand name of Levothyroxine may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Levothyroxine may not be used for all of the conditions discussed here.

Your doctor may have suggested Levothyroxine for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are being given Levothyroxine, speak to your doctor. Do not stop using Levothyroxine without consulting your doctor.

Do not give Levothyroxine to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use Levothyroxine if their doctor has not prescribed it.



The dose of levothyroxine depends on how much of the hormone is needed to bring blood levels back to the normal range. This is determined by blood tests that are done in a laboratory. The starting dose will depend on your general physical condition and the severity and length of time that you have been experiencing symptoms of low thyroid hormone levels.

You should take Levothyroxine once a day at the same time every day to ensure a consistent effect. Cotton seed meal, dietary fibre, soybean flour (infant formula), or walnuts may decrease the absorption of levothyroxine.

Signs that you may be getting too much thyroid hormone may include chest pain, increased heart rate, palpitations, excessive sweating, heat intolerance, and nervousness. If you think your dose of thyroid hormone may be too high, consult your doctor as soon as possible.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are using the medication without consulting your doctor.

It is important to take Levothyroxine exactly as recommended by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Levothyroxine at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Levothyroxine. If you are concerned about side effects, discuss the risks and benefits of Levothyroxine with your doctor.

The following side effects have been reported by at least 1% of people taking Levothyroxine. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • Diarrhea
  • Fever
  • hair loss (temporary; particularly in children during the first month of treatment)
  • headache
  • increased appetite
  • increased sweating
  • leg cramps
  • menstrual cycle changes
  • muscle weakness
  • nervousness or irritability
  • sensitivity to heat
  • stomach cramps
  • tremor (shaking)
  • trouble sleeping
  • upset stomach
  • weight changes

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Stop taking the medication and seek immediate medical attention if any of the following occur:

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Levothyroxine.


Available form

Each single-dose vial contains 500 µg of levothyroxine sodium. Nonmedicinal ingredients: mannitol, tribasic sodium phosphate anhydrous, and sodium hydroxide.



Do not take Levothyroxine if you:

  • are allergic to levothyroxine or any ingredients of the medication
  • are having a Heart Attack
  • have acute thyrotoxicosis (too much thyroid hormone in their system)
  • have uncorrected adrenal insufficiency



There may be an interaction between levothyroxine and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Levothyroxine. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.



Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Levothyroxine.

Bone density: Levothyroxine can cause bones to lose thickness. If you have an increased risk for Osteoporosis (bone thinning) or are taking medications that reduce bone thickness (e.g., Prednisone or antiseizure medications), before you start taking Levothyroxine, discuss with your doctor how Levothyroxine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Levothyroxine, and whether any special monitoring is needed.

Your doctor may monitor your bone thickness while you are taking Levothyroxine.

Diabetes: Levothyroxine raises blood sugar levels. For people with diabetes, this may result in an increase in the requirements for insulin or antidiabetes medications. If you have diabetes or are at an increased risk of developing diabetes, discuss with your doctor how Levothyroxine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Levothyroxine, and whether any special monitoring is needed.

You may need to monitor your blood sugar more closely when starting Levothyroxine or changing doses of Levothyroxine.

Heart disease: When starting levothyroxine, people with heart disease may be started on a lower dosage as it may cause the heart to work harder than it has been used to. If you have heart disease, discuss with your doctor how Levothyroxine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Levothyroxine, and whether any special monitoring is needed.

Signs of getting too much or too little medication: Contact your doctor as soon as possible if you notice any signs of getting too much medication (such as chest pain, confusion, fast or irregular heartbeat, mood swings, muscle weakness, psychosis, extreme restlessness, yellow eyes or skin, or shortness of breath) or signs of not getting enough medication (such as clumsiness, coldness, Constipation, dry, puffy skin, listlessness, muscle aches, sleepiness, tiredness, weakness, or weight gain).

Weight loss: Levothyroxine should not be used for weight loss. Large doses of levothyroxine can cause serious ore even life threatening side effects especially when taken together with other medications for weight loss.

Pregnancy: Levothyroxine should be taken throughout pregnancy to regulate the levels of thyroid hormone for the pregnant mother and the developing baby. If you become pregnant while taking Levothyroxine, contact your doctor as soon as possible. Your doctor may want to monitor your thyroid function more closely while you are pregnant.

Breast-feeding: Only a small amount of thyroid hormone is passed into breast milk. The use of appropriate amounts of Levothyroxine by breast-feeding women has not been shown to cause harm for breast-fed babies.

Seniors: Seniors may be more sensitive to the effects of levothyroxine.

Levothyroxine frequently asked questions

How To Buy Levothyroxine Online?

You can buy Levothyroxine online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Levothyroxine?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Levothyroxine in Canada?

Shipping cost for Levothyroxine to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

How to get Levothyroxine delivered to my home?

You could get Levothyroxine delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Levothyroxine in Canada for free?

You can get Levothyroxine for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Levothyroxine for free.

Can I consult a doctor online to get Levothyroxine?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Levothyroxine.

Can I buy Levothyroxine without a prescription?

You need a valid prescription to buy Levothyroxine from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.


All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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