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Allopurinol is an inhibitor of xanthine oxidase, a substance in the body that is responsible for the product of uric acid. It is used to prevent Gout, Kidney Stones, and kidney damage caused by uric acid.
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Allopurinol is an inhibitor of xanthine oxidase, a substance in the body that is responsible for the product of uric acid. It is used to prevent Gout, Kidney Stones, and kidney damage caused by uric acid. It is also used to reduce the levels of uric acid in the blood that occur because of blood disorders associated with cancer such as leukemias and lymphomas.
Apo Allopurinol may be available under multiple brand names and/or in several different forms. Any specific brand name of Apo Allopurinol may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Apo Allopurinol may not be used for all of the conditions discussed here.
Your doctor may have suggested Apo Allopurinol for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Apo Allopurinol, speak to your doctor. Do not stop taking Apo Allopurinol without consulting your doctor.
Do not give Apo Allopurinol to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Apo Allopurinol if their doctor has not prescribed it.
The recommended dose ranges from 100 mg to 800 mg daily in 1 to 3 divided doses, depending on the condition being treated. Take allopurinol after eating, to help minimize upset stomach.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Apo Allopurinol exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store at room temperature in a dry place and keep out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Apo Allopurinol. If you are concerned about side effects, discuss the risks and benefits of Apo Allopurinol with your doctor.
The following side effects have been reported by at least 1% of people taking Apo Allopurinol. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Apo Allopurinol.
Each white, round, biconvex, scored tablet engraved "ALL" over “100” on one side contains 100 mg of allopurinol. Nonmedicinal ingredients: croscarmellose sodium, magnesium stearate and colloidal silicon dioxide.
Each peach coloured, round, biconvex, scored tablet engraved "ALL" over “200” on one side contains 200 mg of allopurinol. Nonmedicinal ingredients: croscarmellose sodium, magnesium stearate and colloidal silicon dioxide, Sunset Yellow Aluminium Lake 40%.
Each orange, round, biconvex, scored tablet engraved "ALL" over “300” on one side contains 300 mg of allopurinol. Nonmedicinal ingredients: croscarmellose sodium, magnesium stearate and colloidal silicon dioxide, Sunset Yellow Aluminium Lake 40%.
Do not take Apo Allopurinol if you:
There may be an interaction between allopurinol and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Apo Allopurinol. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Apo Allopurinol.
Drowsiness/reduced alertness: Apo Allopurinol may cause drowsiness, affecting your ability to drive or operate machinery. Avoid driving, operating machinery, or performing other potentially hazardous tasks until you have determined how you are affected by Apo Allopurinol.
Use appropriate caution if you plan to do activities requiring alertness.
Gout: Do not start allopurinol treatment until an acute attack of gout has completely subsided, as further attacks may be caused by Apo Allopurinol. Acute gout attacks may occur at the start of treatment with allopurinol for people who have not taken the medication before. If an acute gout attack develops after starting Apo Allopurinol, call your doctor.
Hypersensitivity syndrome: A Anaphylaxis (severe allergic reaction) called hypersensitivity syndrome has occurred for some people with the use of allopurinol. This reaction involves a number of organs in the body and may be fatal if not treated quickly. Stop taking the medication and get immediate medical attention if you have symptoms of a severe allergic reaction, including fever, swollen glands, yellowing of the skin or eyes, or flu-like symptoms with skin rash or blistering.
Kidney function: Kidney Disease or reduced kidney function may cause Apo Allopurinol to build up in the body, causing side effects. If you have reduced kidney function or kidney disease, discuss with your doctor how Apo Allopurinol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Allopurinol, and whether any special monitoring is needed.
Liver function: Allopurinol may reduce liver function and can cause liver failure. If you have liver problems, discuss with your doctor how Apo Allopurinol may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Apo Allopurinol, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Apo Allopurinol.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Skin rash: If you develop a skin rash, stop taking Apo Allopurinol and contact your doctor. The skin rash may be the first sign of a serious allergic reaction to the medication.
Pregnancy: Allopurinol is not recommended for women who are or may become pregnant unless the potential benefits outweigh the possible risks. If you are or may be pregnant, talk to your doctor about the risks and benefits of Apo Allopurinol.
Breast-feeding: Apo Allopurinol passes into breast milk. If you are a breast-feeding mother and are taking allopurinol, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Children should not take allopurinol, except in cases where increased uric acid levels in the blood are associated with cancer or with Lesch-Nyhan syndrome. The safety and effectiveness of allopurinol for this age group have not been established in treatment of other conditions.
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All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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