Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Asmanex Twisthaler (Mometasone-furoate-inh). If you are concerned about side effects, discuss the risks and benefits of Asmanex Twisthaler (Mometasone-furoate-inh) with your doctor.

The following side effects have been reported by at least 1% of people taking Asmanex Twisthaler (Mometasone-furoate-inh). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome.

• burning or painful feeling of the tongue
• Constipation
• decreased appetite
• Diarrhea
• dizziness
• Dry Mouth or throat
• ear pain
• fatigue
• headache
• hoarseness or loss of voice
• increased saliva production
• increased sweating
• muscle and joint pain or stiffness
• nasal congestion
• nausea
• sore throat or mouth
• red or itchy eyes
• stomach ache
• thirst
• upset stomach
• vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• cough
• Fever
• irregular menstrual bleeding
• migraine
• Osteoporosis or bone fractures
• pins and needles or numbness of arms or legs, sinus pain and congestion, worsening breathing problems (Churg-Strauss Syndrome)
• signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
• signs of clotting problems (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
• signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
• signs of respiratory tract infection (e.g., fever or chills, shortness of breath, prolonged dizziness, headache, weight loss, tightness in chest, difficulty breathing, or wheezing)
• skin problems (e.g., rash, Hives, chafing, itching, bruising)
• slowed growth (children and adolescents)
• symptoms of adrenal insufficiency (tiredness, headache, nausea, vomiting, muscle or joint pain)
• symptoms of Glaucoma or Cataracts (e.g., blurred vision, seeing halos of bright colours around lights, red eyes, increased pressure in your eyes, eye pain or discomfort)
• wheezing or difficulty breathing right after inhaling the medication
• white patches in the mouth or throat (fungal infection)
• worsening asthma

Stop taking the medication and seek immediate medical attention if any of the following occur:

• chest pain
• increased heart rate
• Anaphylaxis (severe allergic reaction) (e.g., hives; difficulty breathing; or swelling of the face, mouth, or tongue)
• worsening asthma or sudden asthma attacks (e.g., cough, difficulty breathing, wheezing)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Asmanex Twisthaler (Mometasone-furoate-inh).

100 µg/ inhalation
Each metered inhalation from the cap-activated, inhalation driven, dry powder inhaler contains 100 µg of mometasone furoate. Nonmedicinal ingredients: lactose anhydrous.

200 µg/ inhalation
Each metered inhalation from the cap-activated, inhalation driven, dry powder inhaler contains 200 µg of mometasone furoate. Nonmedicinal ingredients: lactose anhydrous.

400 µg/ inhalation
Each metered inhalation from the cap-activated, inhalation driven, dry powder inhaler contains 400 µg of mometasone furoate. Nonmedicinal ingredients: lactose anhydrous.

Do not take inhaled mometasone if you:

• are allergic to mometasone or any ingredients of the medication
• are allergic to milk or lactose
• are having an asthma attack
• have active or inactive lung Tuberculosis
• have an untreated fungal, bacterial, or viral lung infection
• have herpes simplex infection of the eye
• have status asthmaticus (severe, unresponsive asthma)

There may be an interaction between mometasone and any of the following:

• Aldesleukin
• "azole" antifungals (e.g., itraconazole, ketoconazole, Voriconazole)
• Ceritinib
• clarithromycin
• Cobicistat
• Desmopressin
• HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., efavirenz, etravirine, nevirapine)
• HIV protease inhibitors (e.g., atazanavir, indinavir, ritonavir, saquinavir)
• Idelalisib
• mifepristone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Asmanex Twisthaler (Mometasone-furoate-inh). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Asmanex Twisthaler (Mometasone-furoate-inh).

Asthma control: Asmanex Twisthaler (Mometasone-furoate-inh) is not for use as a "reliever" medication. If you start to have an asthma attack, be sure to use your "reliever" medication for rapid relief of your asthma symptoms. Contact your doctor immediately if you find you are using your "reliever" medications (e.g., salbutamol, terbutaline, formoterol) more often or if they are not working as well as they used to. This may mean your asthma is not controlled. Your doctor may want you to temporarily change the dose of Asmanex Twisthaler (Mometasone-furoate-inh) or may start you on an oral corticosteroid.

Eye problems: Prolonged use of mometasone or other inhaled corticosteroids may cause glaucoma with possible damage to the optic nerves or it may produce cataracts. It may also increase the risk of Eye Infections due to fungi or viruses. You should discuss with your doctor how Asmanex Twisthaler (Mometasone-furoate-inh) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Asmanex Twisthaler (Mometasone-furoate-inh), and whether any special monitoring is needed.

Infections: Mometasone may hide some signs of infection, and new infections may appear while mometasone is being used. Infections such as Chickenpox and Measles can be more serious for people taking medications such as mometasone. Contact your doctor if you notice any symptoms of an infection (e.g., fever, chills, cough, sore throat), or if you are in contact with someone who has measles or chickenpox.

Liver function: Mometasone may have increased effects on people who have cirrhosis of the liver. If you have reduced liver function or liver disease, discuss with your doctor how Asmanex Twisthaler (Mometasone-furoate-inh) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Asmanex Twisthaler (Mometasone-furoate-inh), and whether any special monitoring is needed.

Oral hygiene: Adequate oral hygiene, such as rinsing your mouth with water after using Asmanex Twisthaler (Mometasone-furoate-inh), helps reduce the chances of developing thrush, a yeast (fungal) infection of the mouth or throat. If you develop symptoms of thrush, such as white patches in your mouth, contact your doctor.

Osteoporosis: Over time, Asmanex Twisthaler (Mometasone-furoate-inh) can increase the risk of osteoporosis (brittle bones), just as any corticosteroid can. Talk to your doctor about ways to help prevent osteoporosis. Your doctor will monitor your bone density if you need to take Asmanex Twisthaler (Mometasone-furoate-inh) for a long period of time.

Steroid medication use: If you have taken or are still taking an oral steroid medication (e.g., Prednisone) during the last several months, consult your doctor before using Asmanex Twisthaler (Mometasone-furoate-inh). In times of stress or during a severe asthma attack, your doctor may want you to start your steroid medication again.

Stopping medication: Do not stop Asmanex Twisthaler (Mometasone-furoate-inh) abruptly. When Asmanex Twisthaler (Mometasone-furoate-inh) is stopped, it should be stopped gradually, as directed by your doctor.

Thyroid disease: The effects of mometasone may be increased for people with decreased thyroid function (Hypothyroidism). If you have hypothyroidism, discuss with your doctor how Asmanex Twisthaler (Mometasone-furoate-inh) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Asmanex Twisthaler (Mometasone-furoate-inh), and whether any special monitoring is needed.

Wheezing: Asmanex Twisthaler (Mometasone-furoate-inh) may cause the airways to spasm immediately after using the inhaler. If this happens, use your rescue inhaler as soon as possible to relieve the symptoms, then call your doctor as soon as possible.

Pregnancy: Asmanex Twisthaler (Mometasone-furoate-inh) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Asmanex Twisthaler (Mometasone-furoate-inh), contact your doctor immediately.

Breast-feeding: It is not known if mometasone passes into breast milk. If you are a breast-feeding mother and are taking Asmanex Twisthaler (Mometasone-furoate-inh), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Inhaled mometasone may slow the growth and development of adolescents using Asmanex Twisthaler (Mometasone-furoate-inh). This will be closely monitored by your child's doctor. The safety and effectiveness of inhaled mometasone has not been determined for children less than 4 years of age.