Zydelig

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Available Form:  

TABLET

Manufacturer name:  

Gilead Sciences

Generic name:  

IDELALISIB

Strength:  

100MG

What is Zydelig?

Zydelig (Idelalisib) belongs to the group of cancer-fighting medications known as antineoplastics and more specifically to a class of medications called kinase inhibitors. These medications slow the reproduction of cancerous cells and kills cancerous cells.

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Zydelig frequently asked questions

How To Buy Zydelig Online?

You can buy Zydelig online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Zydelig?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Zydelig in Canada?

Shipping cost for Zydelig to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Zydelig delivered to my home?

You could get Zydelig delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Zydelig in Canada for free?

You can get Zydelig for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Zydelig for free.

Can I consult a doctor online to get Zydelig?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Zydelig.

Can I buy Zydelig without a prescription?

You need a valid prescription to buy Zydelig from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

Zydelig Uses

Zydelig (Idelalisib) belongs to the group of cancer-fighting medications known as antineoplastics and more specifically to a class of medications called kinase inhibitors. These medications slow the reproduction of cancerous cells and kills cancerous cells.

Zydelig (Idelalisib) is used in combination with another medication, Rituximab, to treat a certain type of cancer of the blood (called Chronic Lymphocytic Leukemia [CLL]) that has been previously treated and then returned (relapsed).

Zydelig (Idelalisib) is also used to treat follicular lymphoma that has been previously treated unsuccessfully at least twice. This is a type of non-Hodgkins lymphoma that affects the white blood cells, called lymphocytes, which play an important role in fighting infections.

Zydelig (Idelalisib) may be available under multiple brand names and/or in several different forms. Any specific brand name of Zydelig (Idelalisib) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Zydelig (Idelalisib) may not be used for all of the conditions discussed here.

Your doctor may have suggested Zydelig (Idelalisib) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Zydelig (Idelalisib), speak to your doctor. Do not stop taking Zydelig (Idelalisib) without consulting your doctor.

Do not give Zydelig (Idelalisib) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Zydelig (Idelalisib) if their doctor has not prescribed it.

Zydelig Dosage

The recommended adult dose of Zydelig (Idelalisib) is 150 mg taken by mouth 2 times a day. Zydelig (Idelalisib) may be taken with food or on an empty stomach.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Zydelig (Idelalisib) exactly as prescribed by your doctor. If you miss a dose and it is more than 6 hours until your next dose, take it as soon as possible and continue with your regular schedule. If it is less than 6 hours until your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Zydelig (Idelalisib) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Zydelig Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Zydelig (Idelalisib). If you are concerned about side effects, discuss the risks and benefits of Zydelig (Idelalisib) with your doctor.

The following side effects have been reported by at least 1% of people taking Zydelig (Idelalisib). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • cold symptoms (e.g., stuffy nose, cough)
  • decreased appetite
  • Diarrhea (mild)
  • fatigue
  • headache
  • heartburn
  • joint or muscle pain
  • mouth sores
  • nausea
  • night sweats
  • stomach pain
  • sun sensitivity
  • trouble sleeping
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • Fever or chills
  • fluid retention (e.g., swelling of the feet, ankles, or lower leg)
  • rash
  • severe diarrhea
  • signs of breathing problems (e.g., shortness of breath, troubled breathing, wheezing, or tightness in chest, fast or irregular breathing)
  • signs of dehydration (e.g., decreased urine, dry skin, dry and sticky mouth, sleepiness, dizziness, headache, thirst, confusion)
  • signs of infection (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • symptoms of a urinary tract infection (e.g., pain when urinating, urinating more often than usual, low back or flank pain)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of a severe skin reaction (e.g., blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort)
  • symptoms of progressive multifocal leukoencephalopathy (e.g., difficulty walking, memory loss, trouble thinking, confusion, vision loss)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Zydelig (Idelalisib).

Zydelig Available form

100 mg
Each orange, oval-shaped, film-coated tablet debossed with "GSI" on one side and the number "100" on the other contains 100 mg of Zydelig (Idelalisib). Nonmedicinal ingredients: microcrystalline cellulose, hydroxypropyl cellulose, croscarmellose sodium, sodium starch glycolate, and magnesium stearate; film coating: Sunset Yellow FCF Aluminum Lake (FD&C Yellow No. 6), polyethylene glycol, talc, polyvinyl alcohol, and titanium dioxide.

150 mg
Each pink, oval-shaped, film-coated tablet debossed with "GSI" on one side and the number "150" on the other contains 150 mg of Zydelig (Idelalisib). Nonmedicinal ingredients: microcrystalline cellulose, hydroxypropyl cellulose, croscarmellose sodium, sodium starch glycolate, and magnesium stearate; film coating: red iron oxide, polyethylene glycol, talc, polyvinyl alcohol, and titanium dioxide.

Zydelig Contraindications

Do not use Zydelig (Idelalisib) if you:

  • are allergic to Zydelig (Idelalisib) or any ingredients of the medication
  • have not previously received at least one other medication to treat CLL or two other medications to treat follicular lymphoma

Zydelig Precautions

There may be an interaction between Zydelig (Idelalisib) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Zydelig (Idelalisib). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Zydelig Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Zydelig (Idelalisib).

Birth control: Women who may become pregnant should use effective birth control while taking Zydelig (Idelalisib) and for at least one month after stopping treatment. Because Zydelig (Idelalisib) may reduce the effectiveness of birth control pills, a barrier form of birth control should also be used.

Diarrhea: People receiving Zydelig (Idelalisib) have experienced severe diarrhea or inflammation of the bowel. If you have a history of inflammatory bowel disease, discuss with your doctor how Zydelig (Idelalisib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zydelig (Idelalisib), and whether any special monitoring is needed.

Gastrointestinal problems can cause diarrhea that may lead to dehydration (loss of too much water from the body). If you experience severe diarrhea for more than a day, or if you have diarrhea along with fever, decreased urination, dizziness, or a fast heartbeat, contact your doctor immediately.

Hypersensitivity syndrome: A Anaphylaxis (severe allergic reaction) called hypersensitivity syndrome has occurred for some people taking Zydelig (Idelalisib). Stop taking the medication and get immediate medical attention if you have symptoms of a severe allergic reaction, including fever, swollen glands, yellowing of the skin or eyes, or flu-like symptoms with skin rash or blistering.

Infection: As well as killing cancer cells, Zydelig (Idelalisib) can reduce the number of cells that fight infection in the body (white blood cells). If possible, avoid contact with people with contagious infections. Tell your doctor immediately if you notice signs of an infection, such as fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness. Your doctor will do blood tests regularly to monitor the number of specific types of blood cells in your blood.

Serious and sometimes life-threatening infections can occur when taking Zydelig (Idelalisib). Antibiotics are often taken to prevent infections by certain bacteria during treatment with Zydelig (Idelalisib) and for several months after stopping Zydelig (Idelalisib).

Liver function: Liver disease or reduced liver function may cause Zydelig (Idelalisib) to build up in the body, causing side effects. Zydelig (Idelalisib) may also reduce liver function and can cause liver failure. If you have liver problems, discuss with your doctor how Zydelig (Idelalisib) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Zydelig (Idelalisib), and whether any special monitoring is needed. Your doctor will want to test your liver function regularly with blood tests while you are taking Zydelig (Idelalisib).

Zydelig (Idelalisib) is not recommended for people with hepatitis or active liver disease.

Lung inflammation: Lung inflammation (pneumonitis) causing difficulty breathing has occurred on rare occasions for some people taking Zydelig (Idelalisib). This complication can be serious and sometimes fatal. If you experience new or worsening shortness of breath or cough (with or without fever) at any time while you are taking Zydelig (Idelalisib), contact your doctor immediately.

Progressive multifocal leukoencephalopathy (PML): There have been reports of PML after using Zydelig (Idelalisib). PML is a rare disorder that causes nerve damage in the brain. If you experience memory loss, vision loss, trouble thinking, or difficulty walking, contact your doctor immediately.

Sensitivity to sunlight: Zydelig (Idelalisib) may increase the sensitivity of the skin to sunlight, increasing the risk of Sunburn. Avoid exposure to sunlight for long periods of time, particularly between the hours of 10 am and 2 pm. Wear a broad-spectrum sunscreen and lip balm with an SPF of 30 or greater. If you notice any unusual skin rash or peeling, contact your doctor immediately.

Pregnancy: Zydelig (Idelalisib) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Zydelig (Idelalisib), contact your doctor immediately.

Breast-feeding: It is not known if Zydelig (Idelalisib) passes into breast milk. If you are breast-feeding and are taking Zydelig (Idelalisib), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Zydelig (Idelalisib) have not been established for children.

Seniors: Seniors may be likely to experience severe side effects from Zydelig (Idelalisib).

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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