Prescription required

Buy Kayexalate Online

FREE Shipping in Canada

Available Form:  


Manufacturer name:  


Generic name:  




What is Kayexalate?

Sodium polystyrene sulfonate belongs to the class of medications called cation-exchange resins. It is used to treat high levels of potassium in the blood (hyperkalemia).

Canada's Leading Online Pharmacy

We make it unbelievably easy to fill prescriptions, consult with pharmacists, and order medications online

What would you like to do?


Refill your Kayexalate prescription

Consult a doctor for Kayexalate over call

Upload your Kayexalate prescription

Enter your phone to save time & money


By proceeding, you agree to our Terms of Use & Privacy Policy. Message and data rates may apply.

Kayexalate Price and Cost Calculator


Total no. of BOTTLE(S)

Insurance coverage

We accept all insurance plans

Estimated copay


Drug cost


Dispensing fee


Delivery cost


Insurance coverage


**Actual price will depend on the insurance coverage in your province

How much does Kayexalate cost?

  • The cost of Kayexalate is $99.85 with us here at PocketPills. The cost of Kayexalate can be lower if your insurance covers it. To calculate the total price of purchasing Kayexalate, you should also consider dispensing and delivery fees.

How much is the dispensing fee for Kayexalate

  • The dispensing cost to order Kayexalate with us is only $7. Pocketpills aims to offer you the most affordable Kayexalate price in Canada.
  • Remember, we offer you FREE Shipping in Canada.



Sodium polystyrene sulfonate belongs to the class of medications called cation-exchange resins. It is used to treat high levels of potassium in the blood (hyperkalemia).

It lowers the level of potassium in the blood by binding to potassium in the intestine.

Kayexalate (Polystyrene-sulfonate-sodium) may be available under multiple brand names and/or in several different forms. Any specific brand name of Kayexalate (Polystyrene-sulfonate-sodium) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Kayexalate (Polystyrene-sulfonate-sodium) may not be used for all of the conditions discussed here.

Your doctor may have suggested Kayexalate (Polystyrene-sulfonate-sodium) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Kayexalate (Polystyrene-sulfonate-sodium), speak to your doctor. Do not stop taking Kayexalate (Polystyrene-sulfonate-sodium) without consulting your doctor.

Do not give Kayexalate (Polystyrene-sulfonate-sodium) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Kayexalate (Polystyrene-sulfonate-sodium) if their doctor has not prescribed it.



Oral: The average adult dose is 15 grams taken 1 to 4 times daily. Each dose should be mixed in 45 mL to 60 mL of water or syrup. Do not mix it with orange or fruit juice that contains potassium. Children's doses are based on body weight.

Rectal: The recommended adult dose is 30 to 50 grams given 1 or 2 times daily (at intervals of 6 hours). Children's doses are based on body weight.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use Kayexalate (Polystyrene-sulfonate-sodium) exactly as prescribed by your doctor.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Kayexalate (Polystyrene-sulfonate-sodium) at room temperature, protect it from freezing and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Kayexalate (Polystyrene-sulfonate-sodium). If you are concerned about side effects, discuss the risks and benefits of Kayexalate (Polystyrene-sulfonate-sodium) with your doctor.

The following side effects have been reported by at least 1% of people taking Kayexalate (Polystyrene-sulfonate-sodium). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abdominal pain or swelling
  • bleeding from the rectum
  • blood-streaked stool or bloody diarrhea 
  • symptoms of low calcium levels (e.g., abdominal cramps, irritability, muscle spasms)
  • symptoms of low magnesium levels (e.g., muscle weakness, irregular heartbeat, nausea, vomiting)
  • symptoms of low potassium levels (e.g., muscle weakness, irregular heartbeat, nausea, vomiting)
  • symptoms of sodium retention (e.g., bloating, excessive thirst)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of an allergic reaction (such as difficulty breathing, Hives, swelling of the face or throat)  
  • signs of bleeding in the stomach (e.g., vomit that looks like coffee grounds; black, bloody or tarry stools)
  • symptoms of a blocked intestine (e.g., abdominal pain, abdominal swelling, vomiting)
  • symptoms of fecal impaction (e.g., leaking liquid stool, stomach pain, feeling the need to push, nausea, vomiting, loss of appetite)
  • symptoms of a tear of the intestine (e.g., abdominal pain, nausea, vomiting, Fever)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Kayexalate (Polystyrene-sulfonate-sodium).


Available form

Light brown, to brown, finely ground powder of sodium polystyrene sulfonate. The sodium content is approximately 4.1 mmol (100 mg) per gram.



Do not use Kayexalate (Polystyrene-sulfonate-sodium) if you:

  • are allergic to sodium polystyrene sulfonate or any ingredients of the medication
  • have a serum potassium level less than 5 mmol/L
  • have obstructive bowel disease

Sodium polystyrene sulfonate should not be given to newborns by mouth.



There may be an interaction between sodium polystyrene sulfonate and any of the following:

  • aluminum hydroxide
  • certain antacids (e.g., magnesium hydroxide, calcium carbonate)
  • Digoxin
  • laxatives
  • lithium
  • magnesium citrate
  • sorbitol
  • Thyroid replacements (e.g., desiccated thyroid, Levothyroxine)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Kayexalate (Polystyrene-sulfonate-sodium). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.



Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Kayexalate (Polystyrene-sulfonate-sodium).

Increase in sodium levels: Sodium polystyrene sulfonate can cause an increase in sodium levels. If you have Congestive Heart Failure, high blood pressure, kidney problems, or swelling of the ankles, feet, lower legs, or hands, discuss with your doctor how Kayexalate (Polystyrene-sulfonate-sodium) may affect your medical condition and whether special monitoring is required.

Low potassium levels: Sodium polystyrene sulfonate can cause low potassium levels. Tell your doctor if you experience symptoms of low potassium, such as confusion, irregular heartbeat, and muscle weakness or cramping.

Pregnancy: The safety and effectiveness of using Kayexalate (Polystyrene-sulfonate-sodium) during pregnancy have not been established.

Breast-feeding: The safety and effectiveness of using Kayexalate (Polystyrene-sulfonate-sodium) while breast-feeding have not been established.

Children and infants: Newborns should not be given sodium polystyrene sulfonate by mouth.

Kayexalate frequently asked questions

How To Buy Kayexalate Online?

You can buy Kayexalate online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Kayexalate?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Kayexalate in Canada?

Shipping cost for Kayexalate to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

How to get Kayexalate delivered to my home?

You could get Kayexalate delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Kayexalate in Canada for free?

You can get Kayexalate for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Kayexalate for free.

Can I consult a doctor online to get Kayexalate?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Kayexalate.

Can I buy Kayexalate without a prescription?

You need a valid prescription to buy Kayexalate from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.


All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

Reading is good for you...

Reading about what's good for you is even better.

Type 1 and Type 2 Diabetes
All about Erectile Dysfunction (ED) Medications
How Effective Is Bupropion In Treating Seasonal Affective Disorder?

Related Drugs

Related Medical Conditions

Already a member?

Sign In
You're almost there!

Simply sign in to join
our 100k+ satisfied members:



By proceeding, you agree to our Terms of Use & Privacy Policy. Message and data rates may apply.

Prefer to sign up over the phone?

Our care team can't wait to take your call!


Refill your Kayexalate prescription 

You don't have to wait in line at the store to fill your prescriptions. You can have your doctor fax your prescription to them, input the details of your old pharmacy online, or take a picture of your prescription with the online pharmacy app.

Get an online prescription for Kayexalate from a Canadian doctor now

Skip the waiting room! See a Canadian doctor online, for free and get treated for any common condition on your phone. 

*Note: Fully covered with a British Columbia, Alberta, Manitoba or Ontario health card

Upload your Kayexalate prescription

Upload a picture of your prescription(s), allowing us to receive an image of your prescription and begin the process of filling your prescription(s). However, we will require the original hard copy of your prescription to be sent to us in order to complete filling your prescription.