Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Lipidil EZ (Fenofibrate). If you are concerned about side effects, discuss the risks and benefits of Lipidil EZ (Fenofibrate) with your doctor.

The following side effects have been reported by at least 1% of people taking Lipidil EZ (Fenofibrate). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• Constipation
• decreased interest in sexual activity
• Diarrhea
• dizziness
• fatigue
• gas
• hair loss
• headache
• increased sensitivity of skin to sunlight
• joint pain
• nausea
• red, itchy skin
• skin rash
• stomach pain
• trouble sleeping
• vomiting
• weight loss

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• signs of liver problems such as dark urine, general feeling of being unwell, loss of appetite, nausea, vomiting, or yellowing of the eyes or skin
• signs of muscle damage (e.g., unexplained muscle pain, tenderness or weakness, or brown or discoloured urine)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• signs of a blood clot in the arm or leg (tenderness, pain, swelling, warmth, or redness in the arm or leg) or lungs (difficulty breathing, sharp chest pain that is worse when breathing in, coughing, coughing up blood, sweating, or passing out)
• signs of pancreatitis (e.g., abdominal pain on the upper left side, back pain, nausea, Fever, chills, rapid heartbeat, swollen abdomen)
• signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Lipidil EZ (Fenofibrate).

48 mg
Each yellow, oblong, film-coated tablet embossed with the Fournier logo on one side and "48" on the other contains 48 mg of Lipidil EZ (Fenofibrate). Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, Docusate Sodium, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, and sucrose; coating: D&C Blue No. 2/Indigo Carmine FCF Aluminum Lake, D&C Yellow No. 6/Sunset Yellow FCF Aluminum Lake, D&C Yellow No. 10 Aluminum Lake, lecithin, polyvinyl alcohol, talc, and titanium dioxide.

145 mg
Each white, oblong, film-coated tablet embossed with the Fournier logo on one side and "145" on the other contains 145 mg of Lipidil EZ (Fenofibrate). Nonmedicinal ingredients: colloidal silicon dioxide, crospovidone, docusate sodium, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate, and sucrose; coating: polyvinyl alcohol, soybean lecithin, talc, titanium dioxide, and xanthan gum.

Do not take Lipidil EZ (Fenofibrate) (crystals) if you:

• are allergic to Lipidil EZ (Fenofibrate) or any ingredients of the medication
• are allergic to any other medication in the fibrate class (e.g., Gemfibrozil, Bezafibrate, clofibrate)
• are allergic to peanut or arachis oil, soya lecithin, or any related products
• are pregnant or breast-feeding
• are taking a "statin" cholesterol-lowering medication and have muscle problems
• have gallbladder disease
• have had a severe skin reaction to other fibrates (e.g., gemfibrozil, bezafibrate, clofibrate) or Ketoprofen
• have pancreatitis
• have reduced liver function
• have severe reduced kidney function

Do not give Lipidil EZ (Fenofibrate) to children or adolescents less than 18 years of age.

There may be an interaction between Lipidil EZ (Fenofibrate) (crystals) and any of the following:

• Cholestyramine resin
• Colchicine
• Colestipol
• Cyclosporine
• Erlotinib
• Everolimus
• ezetimibe
• raltegravir
• Rosiglitazone
• "statin" medications (e.g., atorvastatin, lovastatin, simvastatin)
• sulfonylurea Diabetes medications (e.g., Gliclazide, Glyburide)
• Tacrolimus
• Ursodiol
• Warfarin

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Lipidil EZ (Fenofibrate). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Lipidil EZ (Fenofibrate).

Blood cells: Lipidil EZ (Fenofibrate) can cause small, temporary decreases in red and white blood cell counts. Your doctor will check for this with blood tests during the first year of treatment.

Combination therapy: The use of Lipidil EZ (Fenofibrate) and "statin" medications (e.g., Atorvastatin, Lovastatin, Simvastatin) at the same time may increase the risk of side effects. Talk to your doctor about the risks and benefits of taking the two types of medications together.

Gallbladder disease: For some people, Lipidil EZ (Fenofibrate) (crystals) aggravates gallbladder disease and can cause gallstones. If you have gallbladder disease, discuss with your doctor how Lipidil EZ (Fenofibrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lipidil EZ (Fenofibrate), and whether any special monitoring is needed. If you experience abdominal or stomach pain, gas, nausea, or bloating (especially after eating high-fat foods), contact your doctor.

Kidney function: People with reduced kidney function may be more at risk of certain side effects when taking Lipidil EZ (Fenofibrate) (crystals). Depending on the degree of kidney function impairment, lower doses of Lipidil EZ (Fenofibrate) (crystals) may be needed. People with severely reduced kidney function and those undergoing dialysis treatment should not take Lipidil EZ (Fenofibrate).

Liver function: If you have reduced liver function or liver disease, discuss with your doctor how Lipidil EZ (Fenofibrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lipidil EZ (Fenofibrate), and whether any special monitoring is needed.

Lipidil EZ (Fenofibrate) (crystals) may cause decreased liver function. If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Muscle problems: Treatment with this type of medication has been associated on rare occasions with muscle pain, usually in people with reduced kidney function. Contact your doctor as soon as possible if you notice unexplained muscle pain, tenderness, or weakness, particularly if you have malaise (a general feeling of illness) or fever.

Pancreatitis: Lipidil EZ (Fenofibrate) can cause the pancreas to become inflamed. If you have a history of pancreatitis, discuss with your doctor how Lipidil EZ (Fenofibrate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lipidil EZ (Fenofibrate), and whether any special monitoring is needed. If you experience severe upper abdominal pain, fever, chills, nausea, or vomiting while taking Lipidil EZ (Fenofibrate), contact your doctor immediately.

Pregnancy: Lipidil EZ (Fenofibrate) should not be used during pregnancy. If you become pregnant while taking Lipidil EZ (Fenofibrate), stop taking it and contact your doctor immediately.

Breast-feeding: It is not known if Lipidil EZ (Fenofibrate) passes into breast milk. If you are a breast-feeding mother and are taking Lipidil EZ (Fenofibrate), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Lipidil EZ (Fenofibrate) have not been established for children.

Seniors: Seniors are more likely to have reduced kidney function and may need lower doses of Lipidil EZ (Fenofibrate).