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Atorvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins") or lipid metabolism regulators. It is used to treat people who have High Cholesterol levels, including those people who have certain inherited cholesterol disorders.
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Atorvastatin belongs to the group of medications known as HMG CoA reductase inhibitors ("statins") or lipid metabolism regulators. It is used to treat people who have High Cholesterol levels, including those people who have certain inherited cholesterol disorders. When you use Ratio Atorvastatin, you also need to make lifestyle changes, including switching to a diet low in fat and cholesterol, quitting smoking, and increasing the amount of exercise you do.
Atorvastatin works by blocking an enzyme that is used to make cholesterol in the liver. When that enzyme is blocked, less cholesterol is produced and the amount of cholesterol in the blood decreases. Atorvastatin lowers the level of total cholesterol and low density lipoprotein (LDL, or "bad" cholesterol), and raises high density lipoprotein (HDL, or "good" cholesterol) levels. Reduction of cholesterol levels in the blood has been shown to reduce the risks associated with heart disease, such as Heart Attack.
Atorvastatin is used to reduce the risk of heart attack in people experiencing symptoms associated with heart disease.
Atorvastatin is also used to reduce the risk of heart attack in people with high blood pressure who have at least 3 additional risk factors for heart disease but are not experiencing symptoms associated with heart disease. The risk factors of heart disease for these individuals include:
Atorvastatin is also used to reduce the risk of heart attack and Stroke in people with high blood pressure and type 2 diabetes who have other risk factors for heart disease but are not experiencing symptoms associated with heart disease. The risk factors of heart disease for these individuals include:
Atorvastatin may be used in addition to diet to reduce cholesterol for adolescents between 10 and 17 years of age with increased cholesterol levels and family history of early heart disease or 2 or more risk factors for cardiovascular disease.
The medication usually takes about 2 to 4 weeks to have a significant effect on the cholesterol level in your blood. After this time, your doctor will likely send you for a blood test to check for changes in your cholesterol levels.
Ratio Atorvastatin may be available under multiple brand names and/or in several different forms. Any specific brand name of Ratio Atorvastatin may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Ratio Atorvastatin may not be used for all of the conditions discussed here.
Your doctor may have suggested Ratio Atorvastatin for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Ratio Atorvastatin, speak to your doctor. Do not stop taking Ratio Atorvastatin without consulting your doctor.
Do not give Ratio Atorvastatin to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Ratio Atorvastatin if their doctor has not prescribed it.
When you start taking atorvastatin, you should be on a cholesterol-lowering diet. If appropriate, a health care professional will discuss an individualized program of weight control and physical exercise with you.
The recommended starting dose of atorvastatin for adults is 10 mg or 20 mg daily, preferably in the evening, with or without food. Your doctor will do blood tests to tell how well this dose is working for you and may gradually increase the dose to get the desired response. The maximum recommended dose for adults is 80 mg taken once daily.
For children 10 to 17 years of age who are taking Ratio Atorvastatin to treat inherited cholesterol disorders, the recommended dose ranges from 10 mg to 20 mg daily. Doses greater than 20 mg have not been studied.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
For best results in lowering cholesterol, it is very important to closely follow the diet suggested by your doctor. It is also very important that atorvastatin be taken regularly and exactly as prescribed by your doctor.
If you miss a dose of Ratio Atorvastatin, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Ratio Atorvastatin at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Ratio Atorvastatin. If you are concerned about side effects, discuss the risks and benefits of Ratio Atorvastatin with your doctor.
The following side effects have been reported by at least 1% of people taking Ratio Atorvastatin. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Ratio Atorvastatin.
Atorvastatin by Ratiopharm is no longer being manufactured for sale in Canada. For brands that may still be available, search under atorvastatin. This article is being kept available for reference purposes only. If you are using Ratio Atorvastatin, speak with your doctor or pharmacist for information about your treatment options.
Do not take Ratio Atorvastatin if you:
There may be an interaction between atorvastatin and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Ratio Atorvastatin. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Ratio Atorvastatin.
Alcohol: People who drink large quantities of alcohol should be closely monitored by their doctor while they are taking Ratio Atorvastatin.
Cardiovascular: There is an increased risk of hemorrhagic stroke if atorvastatin is started within 6 months of having a stroke or Transient Ischemic Attack (TIA). If you have a history of stroke or have had a recent stroke, discuss with your doctor how Ratio Atorvastatin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ratio Atorvastatin, and whether any special monitoring is needed.
Diabetes: Atorvastatin may cause an increase in blood sugar levels and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Ratio Atorvastatin.
If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Ratio Atorvastatin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ratio Atorvastatin, and whether any special monitoring is needed.
Diet: Atorvastatin is not intended to be used alone to reduce high cholesterol levels. It is important that a cholesterol-reducing diet along with appropriate exercise be attempted before taking any medication and continued while taking medication.
Grapefruit juice: Taking atorvastatin and consuming grapefruit juice may result in an increased amount of atorvastatin in the body, and lead to side effects. If you regularly drink grapefruit juice, talk to your doctor or pharmacist about whether you should change your diet.
Kidney function: If you have decreased kidney function or a history of Kidney Disease, you may be at an increased risk of developing muscle effects while taking atorvastatin. The lowest effective dose of atorvastatin should be used and your doctor should follow you closely. If you have kidney problems, discuss with your doctor how Ratio Atorvastatin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ratio Atorvastatin, and whether any special monitoring is needed.
Liver function: Atorvastatin may reduce liver function and can cause liver failure. Ratio Atorvastatin should not be used by people with active liver disease or by people whose liver function tests are higher than normal. If you have liver problems, discuss with your doctor how Ratio Atorvastatin may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Ratio Atorvastatin, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Ratio Atorvastatin.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Muscle effects: In rare cases, serious muscle pain, cramps, and weakness have been associated with the use of statin medications (i.e., cholesterol-lowering medications whose names end in "statin," such as atorvastatin, Fluvastatin, Lovastatin, Pravastatin, Rosuvastatin, or Simvastatin), especially at higher doses. Before taking Ratio Atorvastatin, tell your doctor or pharmacist if you:
Report any unexplained muscle pain, tenderness, weakness, or cramps, or any brown or discoloured urine to your doctor immediately, particularly if you are also experiencing malaise (a general feeling of being unwell) or fever.
Pregnancy: Cholesterol is necessary for the development of an unborn baby. Taking atorvastatin during pregnancy reduces the amount of cholesterol reaching the developing baby and may cause harm to the baby. Atorvastatin should not be taken by pregnant women. If you become pregnant while taking Ratio Atorvastatin, stop taking it immediately and contact your doctor.
Breast-feeding: It is not known if atorvastatin passes into breast milk. If you are a breast-feeding mother and are taking Ratio Atorvastatin, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: There is limited experience with the use of Ratio Atorvastatin by children. Atorvastatin has only been studied for use by children aged 10 to 17 years who have inherited cholesterol disorders (also known as familial hypercholesterolemia).
Seniors: If you are more than 70 years old, you may experience more side effects. Your doctor will monitor you closely while you are taking Ratio Atorvastatin.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
August 8, 2022
August 10, 2022
August 2, 2022