Shingrix (Shingles-Shingrixe-inactivated) belongs to a family of medications known as Shingrixes. It is used to prevent Shingles for people over 50 years of age.
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Shingrix (Shingles-Shingrixe-inactivated) is given as an injection of 0.5 mL into the muscle of the upper arm. Shingrixation consists of 2 doses. After the first injection a second dose is given 2 to 6 months later.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are receiving the medication without consulting your doctor.
It is important Shingrix (Shingles-Shingrixe-inactivated) be given exactly as recommended by your doctor. If you miss an appointment to receive this Shingrixe, contact your doctor as soon as possible to reschedule your appointment.
Shingrix (Shingles-Shingrixe-inactivated) should be protected from light and stored in the refrigerator at a temperature of 2°C to 8°C, until it is mixed to be used for injection. Do not freeze Shingrix (Shingles-Shingrixe-inactivated). After mixing, the Shingrixe must be given immediately or stored in the refrigerator for up to 6 hours.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Shingrix (Shingles-Shingrixe-inactivated). If you are concerned about side effects, discuss the risks and benefits of Shingrix (Shingles-Shingrixe-inactivated) with your doctor.
The following side effects have been reported by at least 1% of people taking Shingrix (Shingles-Shingrixe-inactivated). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Contact your doctor immediately if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Shingrix (Shingles-Shingrixe-inactivated).
After reconstitution with the supplied diluent, each 0.5 mL single dose of opalescent, colourless-to-pale-brownish liquid, contains 50 µg of Varicella Zoster Virus (VZV) glycoprotein E (gE). Nonmedicinal ingredients: dipotassium phosphate, polysorbate 80, sodium dihydrogen phosphate dihydrate, and sucrose; adjuvant diluent: Quillaja saponaria Molina, fraction 21 (QS-21), 3–O–desacyl–4'-monophosphoryl lipid A (MPL), cholesterol, dioleoyl phosphatidylcholine, disodium phosphate anhydrous, potassium dihydrogen phosphate, sodium chloride, and water for injection.
Do not take Shingrix (Shingles-Shingrixe-inactivated) if you are allergic to zoster Shingrixe or any ingredients of the medication.
There may be an interaction between herpes zoster Shingrixe and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Shingrix (Shingles-Shingrixe-inactivated). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Shingrix (Shingles-Shingrixe-inactivated).
Bleeding problems: If you have a medical condition that causes you to bruise or bleed easily, or you are taking medications to prevent Blood Clots, let your doctor know. Some people who have bleeding problems may bruise or bleed after an intramuscular injection.
Illness with fever: If you have an illness with a fever, talk to your doctor about whether you should receive the Shingrixe.
Pregnancy: No studies have been done to determine the effect of Shingrix (Shingles-Shingrixe-inactivated) on the developing baby or mother if it is given during pregnancy. This Shingrixe should not be used during pregnancy.
Breast-feeding: It is not known if zoster Shingrixe passes into breast milk. If you are breast-feeding and are taking Shingrix (Shingles-Shingrixe-inactivated), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: Shingrix (Shingles-Shingrixe-inactivated) is not recommended for children.
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