Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Pdp Amantadine. If you are concerned about side effects, discuss the risks and benefits of Pdp Amantadine with your doctor.

The following side effects have been reported by at least 1% of people taking Pdp Amantadine. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• agitation
• anxiety and irritability
• Constipation
• Diarrhea
• dizziness or lightheadedness
• drowsiness
• Dry Mouth
• headache
• loss of appetite
• nausea
• nervousness
• nightmares or vivid dreams
• purplish-red blotchy spots on skin
• trouble sleeping

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• confusion
• hallucinations (seeing or hearing things that are not there)
• poor muscle coordination
• problems urinating
• signs of Depression, e.g.:
• changes in sleep
• changes in weight
• decreased interest in activities
• poor concentration
• thoughts of suicide
• signs of heart problems (e.g., swelling of the hands, feet, or lower legs, difficulty breathing)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• seizures
• symptoms of a Anaphylaxis (severe allergic reaction) (e.g., swelling of the hands, feet, ankles, face, lips, mouth, or throat; difficulty breathing or swallowing)
• thoughts of suicide or attempts at suicide

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Pdp Amantadine.

Do not use Pdp Amantadine if you are allergic to amantadine or any ingredients of the medication.

There may be an interaction between amantadine and any of the following:

• alcohol
• antiarrhythmics (e.g., amidarone, Disopyramide, Dronedarone, procainamaide, quinidine)
• anticholinergics (e.g., atropine, scopolamine)
• antihistamines (e.g., Dimenhydrinate, Diphenhydramine)
• antipsychotics (e.g., Clozapine, Haloperidol, quietiapine, Risperidone)
• Bupropion
• central nervous system stimulants (e.g., Methylphenidate, Modafinil)
• Domperidone
• efavirenz
• glycopyrrolate
• Hydrochlorothiazide
• influenza vaccine
• Leuprolide
• levodopa
• lopinavir
• macrolide antibiotics (e.g., azithromycin, clarithromycin, erythromycin)
• Memantine
• Methadone
• Metoclopramide
• mifepristone
• nolotinib
• Primaquine
• quinine
• quinolone antibiotics (e.g., ciprofloxacin, levofloxacin, Ofloxacin)
• selective serotonin reuptake inhibitors (SSRI; e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
• serotonin antagonists (e.g., Granisetron, Ondansetron)
• Sotalol
• sulfamethoxazole
• triamterene
• Trimethoprim

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Pdp Amantadine. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Pdp Amantadine.

Behaviour changes and suicidal thoughts: There have been reports of behaviour changes and thoughts of suicide or wanting to harm others in people who have taken amantadine. If you experience these symptoms or any other behaviour changes while taking Pdp Amantadine, contact your doctor immediately. Family members or caregivers of people who are taking Pdp Amantadine should contact your doctor immediately if they notice unusual behaviour changes.

Congestive Heart Failure: Amantadine can cause side effects that contribute to heart failure. If you have a history of congestive heart failure or fluid retention, discuss with your doctor how Pdp Amantadine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pdp Amantadine, and whether any special monitoring is needed.

Dental problems: Amantadine may cause a decrease in saliva flow and increase the risk of cavities, periodontal disease, oral Candidiasis (fungal infection), and discomfort. Your doctor, dentist, or pharmacist may be able to suggest ways to reduce these effects.

Drowsiness/reduced alertness: Amantadine may cause drowsiness or blurred vision. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how Pdp Amantadine affects you.

Effectiveness: The benefit of amantadine has not been seen for the treatment of flu symptoms that have been present for more than 2 days.

Flu shots: Amantadine is not a substitute for the flu shot. Continue to receive an annual flu shot as advised by your doctor.

Glaucoma: Amantadine can cause your pupils to dilate, affecting the severity of glaucoma. If you have angle closure glaucoma, discuss with your doctor how Pdp Amantadine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pdp Amantadine, and whether any special monitoring is needed.

Liver disease: If you have a history of liver disease, discuss with your doctor how Pdp Amantadine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pdp Amantadine, and whether any special monitoring is needed.

Mental conditions: If you have a mental health condition, discuss with your doctor how Pdp Amantadine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pdp Amantadine, and whether any special monitoring is needed.

Neuroleptic malignant syndrome (NMS): Neuroleptic malignant syndrome has been reported in people who reduced or stopped taking amantadine. It is an uncommon but life-threatening syndrome characterized by Fever, muscle stiffness, involuntary movements, altered consciousness, increased heart rate and breathing rate, and fluctuating blood pressure. If you experience any of these symptoms, seek immediate medical attention.

Parkinson's disease: People with Parkinson's disease whose condition improves with amantadine treatment should gradually and cautiously resume normal activities until they determine their ability to tolerate Pdp Amantadine. Do not suddenly stop taking amantadine for Parkinson's disease as this may cause a sudden worsening of your condition.

Rash: If you have a history of recurrent (eczematoid) rash, discuss with your doctor how Pdp Amantadine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pdp Amantadine, and whether any special monitoring is needed.

Seizures: Amantadine may cause seizure if you are at risk of experiencing seizures. If you have a history of Epilepsy or other seizures, discuss with your doctor how Pdp Amantadine may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pdp Amantadine, and whether any special monitoring is needed.

Pregnancy: Pdp Amantadine can cause birth defects if it is taken by pregnant women. Amantadine should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Pdp Amantadine, contact your doctor immediately.

Breast-feeding: Pdp Amantadine passes into breast milk. If you are a breast-feeding mother and are taking amantadine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding. Amantadine is not recommended for use by breast-feeding mothers.

Children: The safety and effectiveness of using Pdp Amantadine have not been established for newborns and infants under one year old.

Seniors: Seniors are more likely to experience side effects with normal adult doses of amantadine. As a result, they may require a lower dose of amantadine.