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Multaq (Dronedarone) belongs to the class of medications called antiarrhythmics. It is used to help control an abnormal heart rate and rhythm called atrial fibrillation and can lower the risk of having to go the hospital for heart problems or the risk of death.
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Multaq (Dronedarone) belongs to the class of medications called antiarrhythmics. It is used to help control an abnormal heart rate and rhythm called atrial fibrillation and can lower the risk of having to go the hospital for heart problems or the risk of death. It works by affecting how electrical impulses affect the heart muscle. Multaq (Dronedarone) should only be used after other treatment options have been considered.
Your doctor may have suggested Multaq (Dronedarone) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Multaq (Dronedarone), speak to your doctor. Do not stop taking Multaq (Dronedarone) without consulting your doctor.
Do not give Multaq (Dronedarone) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Multaq (Dronedarone) if their doctor has not prescribed it.
The usual recommended dose of Multaq (Dronedarone) for adults is 400 mg twice daily with the morning and evening meal. People taking Multaq (Dronedarone) should avoid drinking grapefruit juice or eating grapefruit, as this can increase the blood levels of Multaq (Dronedarone) and lead to side effects and other problems.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that Multaq (Dronedarone) be taken exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Multaq (Dronedarone) at room temperature in its original package and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Multaq (Dronedarone). If you are concerned about side effects, discuss the risks and benefits of Multaq (Dronedarone) with your doctor.
The following side effects have been reported by at least 1% of people taking Multaq (Dronedarone). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Multaq (Dronedarone).
Each white film-coated tablet for oral administration, oblong-shaped, engraved with a double wave marking on one side and "4142" code on the other side contains Multaq (Dronedarone) hydrochloride equivalent to Multaq (Dronedarone) 400 mg. Nonmedicinal ingredients: colloidal anhydrous silica, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, maize starch, and poloxamer 407; coating: carnauba wax, hypromellose, macrogol 6000, and titanium dioxide.
Do not take Multaq (Dronedarone) if you:
There may be an interaction between Multaq (Dronedarone) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Multaq (Dronedarone). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Multaq (Dronedarone).
Congestive heart failure: If you have moderate congestive heart failure, discuss with your doctor how Multaq (Dronedarone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Multaq (Dronedarone), and whether any special monitoring is needed. This medication should not be used for people with severe congestive heart failure. People with severe heart failure who take Multaq (Dronedarone) have an increased chance of dying. If you develop heart failure symptoms or worsening symptoms (e.g., weight gain, increasing shortness of breath, difficulty breathing at night, swelling of the feet or legs) while taking Multaq (Dronedarone), contact your doctor immediately.
Lung problems: Multaq (Dronedarone) can cause lung problems (Pulmonary Fibrosis, inflammation of lung tissue). Tell your doctor immediately if you experience any difficulty breathing, shortness of breath, or Dry Cough while you are taking Multaq (Dronedarone).
Kidney function: The results of a blood test for kidney function, called creatinine, may be increased without a change in your kidney function. Your doctor will use the creatinine level as your new normal. Tell any other doctor you see about the new "normal" value of your blood creatinine.
Liver: There have been reports of liver injury in people who were taking Multaq (Dronedarone). Your doctor may regularly perform tests to monitor your liver function. If you experience symptoms of liver damage (e.g., yellowing of the skin or eyes, fatigue, abdominal pain, nausea, vomiting, dark urine, or itching), contact your doctor immediately.
Low potassium and magnesium levels: Before starting and while taking Multaq (Dronedarone), your doctor may want to check your blood levels of potassium and magnesium, especially if you are taking medications (e.g., Hydrochlorothiazide, Furosemide, Indapamide) that may reduce these levels. If they are low, your doctor may recommend that you take supplements or may make changes to your medications.
QT prolongation: Multaq (Dronedarone) can affect the electrical activity of the heart and cause QT prolongation. You doctor will monitor your heart rhythm regularly while you are taking Multaq (Dronedarone) with a test called an electrocardiogram (ECG). You should not take Multaq (Dronedarone) if your ECG already shows that you have QT prolongation or if you are taking a medication that can cause QT prolongation.
Pregnancy: Multaq (Dronedarone) should not be used during pregnancy. If you become pregnant while taking Multaq (Dronedarone), contact your doctor immediately.
Breast-feeding: It is not known if Multaq (Dronedarone) passes into breast milk. Multaq (Dronedarone) should not be used while breast-feeding.
Children: The safety and effectiveness of using Multaq (Dronedarone) have not been established for children under 18 years of age.
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