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Nabumetone belongs to the group of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce pain, swelling, and stiffness caused by Rheumatoid Arthritis and osteoarthritis.
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Nabumetone belongs to the group of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to reduce pain, swelling, and stiffness caused by Rheumatoid Arthritis and osteoarthritis. Nabumetone usually starts to work to relive pain within an hour, but it may take up to 1 week before you feel its full effect.
Nabumetone may be available under multiple brand names and/or in several different forms. Any specific brand name of Nabumetone may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Nabumetone may not be used for all of the conditions discussed here.
Your doctor may have suggested Nabumetone for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Nabumetone, speak to your doctor. Do not stop taking Nabumetone without consulting your doctor.
Do not give Nabumetone to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Nabumetone if their doctor has not prescribed it.
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The recommended dose of nabumetone ranges from 1,000 mg daily to 2,000 mg daily taken in 1 or 2 divided doses, with or without food. If Nabumetone upsets your stomach, take it after a meal or with food or milk. Remain standing for 15 to 30 minutes after taking Nabumetone. It is best to take nabumetone at the same time each day. The tablets should be swallowed whole and not chewed.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Nabumetone exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Nabumetone at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Nabumetone. If you are concerned about side effects, discuss the risks and benefits of Nabumetone with your doctor.
The following side effects have been reported by at least 1% of people taking Nabumetone. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Nabumetone.
Your medication is delivered directly to you at no added cost. We even offer same-day delivery in select locations.
Each white, capsule-shaped, biconvex, film-coated tablet engraved "APO" on one side and "500" on the other contains 500 mg of nabumetone. Nonmedicinal ingredients: croscarmellose sodium, hydroxypropyl cellulose, magnesium stearate, polyethylene glycol, sodium lauryl sulfate, and titanium dioxide.
Do not take Nabumetone if you:
We sort your medication into clearly labeled, individual packs so you can be sure you're taking the right dose at the right time.
There may be an interaction between nabumetone and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Nabumetone. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Nabumetone.
Health Canada has issued new information concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Allergic reactions: If you have had a reaction to acetylsalicylic acid (ASA) or other NSAIDs (e.g., ibuprofen, Ketoprofen, Diclofenac) that included a runny nose, itchy skin rash, nasal polyps, or shortness of breath and wheezing, you should not take Nabumetone. If you experience symptoms of a Anaphylaxis (severe allergic reaction) (e.g., hives; difficulty breathing; wheezing; swelling of the face, tongue, or throat), get immediate medical attention.
Bladder symptoms: Nabumetone can cause bladder symptoms such as frequent or painful urination and blood in urine. If you develop these symptoms, stop taking Nabumetone and contact your doctor immediately.
Drowsiness and dizziness: Nabumetone can cause drowsiness or dizziness. Do not drive or operate machinery until you are sure that Nabumetone does not affect your ability to do these safely.
Fluid and electrolyte balance: Nabumetone can cause fluid retention. If you have heart failure, high blood pressure, or other medical conditions that increase your risk of fluid retention (e.g., kidney problems), discuss with your doctor how Nabumetone may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Nabumetone, and whether any special monitoring is needed.
Nabumetone may also cause high blood potassium levels. If you are a senior; have Diabetes or kidney failure; or are taking beta-blockers (e.g., Metoprolol, Atenolol), angiotensin converting enzyme (ACE) inhibitors (e.g., Ramipril, Enalapril), or some diuretics (e.g., triamterene, Amiloride), you are more at risk of high blood potassium.
Infection: As with other anti-inflammatory medications, nabumetone may mask the usual signs of infection.
Kidney function: Nabumetone can affect kidney function. You have a higher risk of developing kidney problems if you are a senior; take diuretics (water pills; e.g., Hydrochlorothiazide, Furosemide); or already have Kidney Disease, liver disease, or heart failure.
Your doctor may monitor your kidney function with blood tests if you take Nabumetone. If you have kidney disease or reduced kidney function, discuss with your doctor how Nabumetone may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Nabumetone, and whether any special monitoring is needed.
Liver problems: Nabumetone may affect your liver function or cause liver problems. If you experience symptoms of liver problems (e.g., nausea, vomiting, feeling tired, yellowing of the skin or eyes), contact your doctor immediately. If you have liver problems, discuss with your doctor how Nabumetone may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Nabumetone, and whether any special monitoring is needed.
Sun sensitivity: Nabumetone may make your skin more sensitive to sunlight (including sunlamps) and may cause Sunburn; skin blisters; and skin redness, itching, or discolouration. If you have a reaction from the sun while taking Nabumetone, contact your doctor.
Ulcers and bleeding in the stomach and intestines: Nabumetone can cause stomach ulcers, perforation (holes), and bleeding from the stomach. These complications can occur at any time without warning, and are sometimes severe enough to require immediate medical attention. The risk of ulcers and bleeding increases if you are taking higher doses of nabumetone for longer periods of time.
Other factors that increase the risk of these complications include drinking excessive amounts of alcohol, increased age, smoking, poor health, H. pylori infection, and taking certain medications (e.g., Warfarin, ASA, Clopidogrel, Prednisone, Citalopram, Fluoxetine, Paroxetine, Sertraline).
If you currently have ulcers in the stomach or intestines that are bleeding, or have an inflammatory bowel disease (e.g., Crohn's Disease, ulcerative colitis), you should not take Nabumetone. If you have a history of these conditions, discuss with your doctor how Nabumetone may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Nabumetone, and whether any special monitoring is needed.
Stop taking the medication and get immediate medical attention if you experience symptoms or signs of stomach ulcers or bleeding in the stomach (black, tarry stools; blood in stools; stomach pain; vomiting blood or coffee grind material). These reactions can occur at any time during treatment without warning.
Vision: Blurred vision has occasionally been reported with the use of Nabumetone. If this symptom develops, stop taking nabumetone and contact your doctor.
Pregnancy: Nabumetone should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Nabumetone, stop taking it immediately and call your doctor. Nabumetone must not be used during the last 3 months of pregnancy, as it may cause heart and kidney problems for the developing baby and prolonged labour with excessive bleeding during delivery.
Breast-feeding: Taking Nabumetone while breast-feeding is not recommended since the safety of doing so has not been established.
Children: The safety and effectiveness of using Nabumetone have not been established for children.
Seniors: Seniors appear to have a higher risk of developing side effects from Nabumetone. The lowest effective dosage should be used under close medical supervision.
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All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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