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Tremfya

Tremfya

Guselkumab

Tremfya (Guselkumab) belongs to the class of medications called selective immunomodulating agents, also known as biologics. Specifically, it is an interleukin-23 inhibitor.

Available form

Injectable, Injectable

Dosage

100mg, 100mg/1ml

Manufacturers

Janssen

Generic brand of

Guselkumab

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Tremfya information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The usual dose of Tremfya (Guselkumab) is 100 mg injected under the skin. After the first dose, the second dose is given in 4 weeks, and then every 8 weeks for subsequent doses.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Most people using Tremfya (Guselkumab) can be taught by a health care professional to give themselves the injection. Tremfya (Guselkumab) is used with the guidance and supervision of a doctor. Your doctor or nurse will assist you in the preparation and injection of your first dose (or first few doses). Do not attempt to inject Tremfya (Guselkumab) on your own until you completely understand how to inject a dose.

Before using Tremfya (Guselkumab), remove it from the refrigerator and allow it to warm to room temperature, with the cap on. This takes approximately 30 minutes. Do not shake Tremfya (Guselkumab). Shaking causes the medication to become less effective.

Follow the instructions from your doctor or pharmacist when administering the medication. The solution should be clear to slightly yellow and may contain tiny white or clear particles. Do not use the injection if it appears cloudy or discoloured, or if it has large particles floating in it.

Use a different site for each injection to decrease the risk of skin irritation. Dispose of your used needles in an appropriate sharps container.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Tremfya (Guselkumab) in the refrigerator, protect it from freezing, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Tremfya (Guselkumab).

Infections: Tremfya (Guselkumab) can increase the risk of developing an infection, including serious infections such as sepsis, pneumonia, and Tuberculosis. Before starting Tremfya (Guselkumab) treatment, your doctor may test to see if you have tuberculosis. If you notice signs of an infection such as fever, chills, pain, swelling, coughing, or pus, contact your doctor as soon as possible. Tremfya (Guselkumab) should also not be started while you have an active infection.

Tell your doctor if you have a history of infections that keep coming back, or other conditions that might increase your risk of infections such as Diabetes. While you are taking Tremfya (Guselkumab), your doctor will monitor you for signs of infection.

Vaccinations: Vaccines that are given during treatment with Tremfya (Guselkumab) may not be as effective as expected. Also, people taking Tremfya (Guselkumab) should not receive certain vaccines. Talk to your doctor about whether any vaccines you are scheduled to take may be used with Tremfya (Guselkumab).

Pregnancy: Tremfya (Guselkumab) should not be used during pregnancy unless the benefits outweigh the risks. Women who may become pregnant should use effective birth control while taking Tremfya (Guselkumab) and for at least 12 weeks after the last dose of Tremfya (Guselkumab). If you become pregnant while taking Tremfya (Guselkumab), contact your doctor immediately.

Breast-feeding: It is not known if Tremfya (Guselkumab) passes into breast milk. If you are a breast-feeding mother and are taking Tremfya (Guselkumab), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Tremfya (Guselkumab) have not been established for children.

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