Gravol (Dimenhydrinate) belongs to a group of medications called antiemetics. Gravol (Dimenhydrinate) is used to prevent and treat Motion Sickness as well as nausea and vomiting associated with various conditions such as chemotherapy, radiation, and surgery.
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Tablet, Tablet, Capsule, Capsule, Tablet, Injectable, Liquid, Suppository
Dosage
Manufacturer
Alveda Pharmaceuticals, Apotex, Astrazeneca, Avanti Rx Analytics Inc, Bioniche Pharma
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Motion sickness, nausea, vomiting, dizziness, and spinning sensation (vertigo): The usual adult dose of the tablets is 50 mg to 100 mg taken every 4 hours as needed. Do not take more than 400 mg in a 24-hour period. The dose of the long-acting form of Gravol (Dimenhydrinate) tablets is 100 mg every 8 to 12 hours, with a maximum of 3 tablets in a 24-hour period. The usual adult dose of Gravol (Dimenhydrinate) suppository is 50 mg to 100 mg every 6 to 8 hours as needed.
If you are taking Gravol (Dimenhydrinate) for motion sickness, the first dose should be taken at least 30 minutes and preferably 1 to 2 hours before departure.
Pre-radiation therapy (radiation sickness): In adults, 50 mg to 100 mg of Gravol (Dimenhydrinate) may be given as a suppository or injection, 30 to 60 minutes before receiving radiation therapy. This dose may be repeated as needed up to a maximum of 400 mg over a 24-hour period.
Surgery: To control nausea and vomiting following surgery in adults, the usual dose is 50 mg to 100 mg taken by mouth or 50 mg of injection into a muscle before surgery. After surgery, similar doses can be used up to a maximum dose of 400 mg in a 24-hour period.
Children: Follow the dosing instructions provided to you by your doctor or pharmacist or the ones provided with the product being used. Gravol (Dimenhydrinate) should not be used for children or infants under one year old.
For children 2 to 6 years old, the dose of Gravol (Dimenhydrinate) liquid or tablets is 15 mg to 25 mg every 6 to 8 hours as needed to a maximum of 75 mg in a 24-hour period. For the suppositories, the dose in this age group is 12.5 mg to 25 mg. Do not give more than one dose of the suppository form unless recommended by your doctor.
For children 6 to 8 years old, the dose of Gravol (Dimenhydrinate) liquid or tablets is 25 mg to 50 mg every 6 to 8 hours as needed to a maximum of 150 mg in a 24-hour period. For the suppositories, the dose in this age group is 12.5 mg to 25 mg every 8 to 12 hours as needed.
For children 8 to 12 years old, the dose of Gravol (Dimenhydrinate) liquid or tablets is 25 mg to 50 mg every 6 to 8 hours as needed to a maximum of 150 mg in a 24-hour period. For the suppositories, the dose in this age group is 25 mg to 50 mg every 8 to 12 hours as needed.
For children 12 years of age and older, the dose of Gravol (Dimenhydrinate) liquid or tablets is 50 mg every 4 to 6 hours as needed to a maximum of 300 mg in a 24-hours period. For the suppositories, the dose in this age group is 50 mg every 8 to 12 hours as needed.
Chewable tablets and liquid are available for children or adults who are unable to swallow the tablets. When using the liquid, use an oral syringe to measure each dose of the liquid as it gives a more accurate measurement than household teaspoons.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important to use Gravol (Dimenhydrinate) exactly as recommended by your doctor or pharmacist.
Store Gravol (Dimenhydrinate) at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is used in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who uses this medication. If you are concerned about side effects, discuss the risks and benefits of Gravol (Dimenhydrinate) with your doctor.
The following side effects have been reported by at least 1% of people using Gravol (Dimenhydrinate). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Gravol (Dimenhydrinate).
IM Injection
Each mL contains Gravol (Dimenhydrinate) 50 mg. This dosage form is for IM use only, unless diluted at least 1:10 with a compatible physiological solution; i.e., sterile saline or 5% dextrose in water. Nonmedicinal ingredients: methylparaben (multidose vials only), propylene glycol, and propylparaben (multidose vials only). Gravol (Dimenhydrinate) does not contain tartrazine.
100 mg Adult Suppositories
Each white, opaque suppository contains Gravol (Dimenhydrinate) 100 mg adult. Nonmedicinal ingredients: polyethylene glycol, silicon dioxide, and titanium dioxide. Gravol (Dimenhydrinate) does not contain gluten or tartrazine.
Easy-to-Swallow Filmkote tablets
Each round, biconvex, peach coral tablet, intagliated "GRAVOL" on one side and quadrisected on the other, contains Gravol (Dimenhydrinate) 50 mg. Nonmedicinal ingredients: alumina, cellulose, FD&C Yellow No. 6, lactose, magnesium stearate, polyethylene glycol, silicon dioxide, starch (corn), talc, and titanium dioxide. Gravol (Dimenhydrinate) does not contain gluten or tartrazine.
Liquid
Each 5 mL of yellow, transparent, viscous liquid with a bittersweet mixed fruit flavour, contains Gravol (Dimenhydrinate) 15 mg. Nonmedicinal ingredients: citric acid, D&C Yellow No. 10, FD&C Yellow No. 6, flavour, propylene glycol, sodium benzoate, sorbitol, and sucrose.
Children’s Suppositories
Each white, opaque suppository contains Gravol (Dimenhydrinate) 25 mg. Nonmedicinal ingredients: polyethylene glycol, silicon dioxide, and titanium dioxide. Gravol (Dimenhydrinate) does not contain gluten or tartrazine.
Children’s Chewable Tablet
Each round, flat, light purple, cherry-flavored tablet with bevelled edge intagliated GRAVOL 15 on one side, plain on the other side, contains Gravol (Dimenhydrinate) 15 mg. Nonmedicinal ingredients: alumina, aspartame, cellulose, citric acid, FD&C Red No. 40, flavors, magnesium stearate, methacrylic acid copolymer, monoglycerides, polyethylene glycol, sorbitol and starch (corn). Gluten- and tartrazine-free.
Chewable Tablets for Adults
Each round, flat, light pink, orange-flavoured, bevelled-edged tablet, intagliated with "GRAVOL 50" on one side and bisected on the other side, contains Gravol (Dimenhydrinate) 50 mg. Nonmedicinal ingredients: alumina, aspartame, cellulose, citric acid, FD&C Yellow No. 6, flavours, magnesium stearate, methacrylic acid copolymer, monoglycerides, polyethylene glycol, sorbitol, and starch (corn). Gravol (Dimenhydrinate) does not contain gluten or tartrazine.
Softgel Capsules
Each pink, translucent, softgel capsule, printed in white "Gravol", contains Gravol (Dimenhydrinate) 50 mg. Nonmedicinal ingredients: D&C Red No. 33, gelatin, glycerin, mannitol, methylparaben, polyethylene glycol, povidone, propylparaben, sorbitol, and water.
L/A Caplets 100 mg
Each red-white, bilayer, film-coated caplet, intagliated "GRAVOL" on one side, contains Gravol (Dimenhydrinate) 25 mg for immediate release and Gravol (Dimenhydrinate) 75 mg for sustained release. Nonmedicinal ingredients: butyl hydroxytoluene, calcium carbonate, calcium phosphate, FD&C Red No. 40, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyethylene oxide, and starch.
Do not use Gravol (Dimenhydrinate) if you:
There may be an interaction between Gravol (Dimenhydrinate) and any of the following:
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If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Gravol (Dimenhydrinate).
Alcohol: Alcohol may add to the side effects of Gravol (Dimenhydrinate) (e.g., drowsiness) and should be avoided when using Gravol (Dimenhydrinate).
Drowsiness: Gravol (Dimenhydrinate) can cause drowsiness, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until you know how Gravol (Dimenhydrinate) affects you.
Glaucoma: Gravol (Dimenhydrinate) may cause the symptoms of glaucoma (increased pressure in the eye) to become worse. If you have glaucoma, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Gravol (Dimenhydrinate), and whether any special monitoring is needed. Report any changes in vision to your doctor as soon as possible while you are taking Gravol (Dimenhydrinate).
Prostate Problems: Gravol (Dimenhydrinate) may cause the symptoms of an enlarged prostate to become worse. If you have an enlarged prostate, discuss with your doctor how Gravol (Dimenhydrinate) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Pregnancy: Gravol (Dimenhydrinate) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: Gravol (Dimenhydrinate) passes into breast milk. If you are a breast-feeding mother and are taking Gravol (Dimenhydrinate), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Gravol (Dimenhydrinate) have not been established for children under one year of age. Caregivers of children between 1 and 2 years old should contact their child's doctor before giving Gravol (Dimenhydrinate).
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