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Etodolac belongs to the group of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for the short- and long-term relief of Rheumatoid Arthritis and osteoarthritis.
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Etodolac belongs to the group of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for the short- and long-term relief of Rheumatoid Arthritis and osteoarthritis. It works by relieving pain and by reducing swelling and inflammation. It may take up to 2 weeks to see the full benefits of Etodolac.
Etodolac may be available under multiple brand names and/or in several different forms. Any specific brand name of Etodolac may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Etodolac may not be used for all of the conditions discussed here.
Your doctor may have suggested Etodolac for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Etodolac, speak to your doctor. Do not stop taking Etodolac without consulting your doctor.
Do not give Etodolac to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Etodolac if their doctor has not prescribed it.
The usual recommended dose for treatment of rheumatoid arthritis and osteoarthritis is 200 mg to 300 mg twice daily. Some people may find that 400 mg or 600 mg taken once daily in the evening works well. To minimize upset stomach and heartburn, take Etodolac immediately after a meal, or with food or milk.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Etodolac exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Etodolac at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Etodolac. If you are concerned about side effects, discuss the risks and benefits of Etodolac with your doctor.
The following side effects have been reported by at least 1% of people taking Etodolac. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Etodolac.
Each hard gelatin, light grey/dark grey, size No. 0 capsule imprinted "200" contains 200 mg of etodolac. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, lactose monohydrate, stearic acid and talc; capsule: black iron oxide, edible ink, gelatin, sodium lauryl sulfate as a processing aid, titanium dioxide and yellow iron oxide; ink: erythrosine aluminum lake, iron oxide yellow, n-butyl alcohol, propylene glycol, shellac, and titanium dioxide.
Each hard gelatin, light grey/light grey, size No. 0 capsule imprinted "300" contains 300 mg of etodolac. Nonmedicinal ingredients: colloidal silicon dioxide, croscarmellose sodium, lactose monohydrate, stearic acid and talc; capsule: black iron oxide, edible ink, gelatin, sodium lauryl sulfate as a processing aid, titanium dioxide and yellow iron oxide; ink: erythrosine aluminum lake, iron oxide yellow, n-butyl alcohol, propylene glycol, shellac, and titanium dioxide.
Etodolac should not be taken by anyone who:
There may be an interaction between etodolac and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Etodolac. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Etodolac.
Health Canada has issued new information concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Allergy: Some people who are allergic to other anti-inflammatory medications also experience allergic reactions to etodolac. Before you take etodolac, inform your doctor about any previous adverse reactions you have had to medications, especially other NSAIDs. Contact your doctor immediately if you experience signs of an allergic reaction, such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Anemia: As with other nonsteroidal anti-inflammatory drugs (NSAIDs), etodolac can cause a reduced red blood cell count (anemia) or make existing anemia worse. If you have a history of anemia, your doctor may recommend regular blood tests to determine your hemoglobin levels.
If you experience symptoms of reduced red blood cell count such as shortness of breath, feeling unusually tired or pale skin, contact your doctor as soon as possible.
Bleeding: NSAIDs such as etodolac may cause a reduced number of platelets in the blood, which can make it difficult to stop cuts from bleeding. If you notice any signs of bleeding, such as frequent nosebleeds, unexplained bruising, or black and tarry stools, notify your doctor as soon as possible. Your doctor will order routine blood tests to make sure potential problems are caught early.
Be sure to tell your doctor, dentist, or surgeon that you are taking Etodolac. You may be asked to stop taking Etodolac before surgery or dental procedures.
Drowsiness/reduced alertness: Drowsiness, dizziness, and lightheadedness have been reported by some people taking Etodolac. Do not drive vehicles or undertake other potentially hazardous activities until you have determined that Etodolac does not affect you in this way.
Fluid retention: As with many other NSAIDs, people have reported increased fluid retention while taking Etodolac. People who have heart failure, high blood pressure, Kidney Disease, who are recovering from surgical operations under general anesthesia, or have any other condition that might lead to fluid retention should discuss with their doctor how Etodolac may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Etodolac, and whether any special monitoring is needed.
Kidney function: Kidney disease or reduced kidney function may cause Etodolac to build up in the body, causing side effects. If you have kidney problems, heart failure, or you are taking diuretics (e.g., Hydrochlorothiazide, Furosemide, Indapamide) discuss with your doctor how Etodolac may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Etodolac, and whether any special monitoring is needed.
As with other NSAIDs, etodolac may cause kidney damage. If you experience signs of decreased kidney function, such as decreased urine production, difficulty urinating or blood in the urine, contact your doctor as soon as possible.
Liver function: Some people taking NSAIDs such as etodolac have developed liver damage. Stop taking the medication and contact your doctor as soon as possible if you notice signs of liver damage, such as yellow eyes or skin, abdominal pain, itchy skin, pale stools, or dark urine. Your doctor may recommend regular liver function tests if you are taking Etodolac for a long period of time.
Potassium: NSAIDs such as etodolac can increase blood levels of potassium. You doctor will check your blood potassium levels while you are taking Etodolac. People with Diabetes, kidney failure, or who are seniors, or are taking certain medications (e.g., Ramipril, Amiloride) should discuss with their doctor how Etodolac may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Etodolac, and whether any special monitoring is needed.
Ulcers: NSAIDs such as etodolac may increase the risk of ulcers in the stomach and intestines. If you have had an ulcer, are at risk of experiencing an ulcer (e.g., are senior or smoke), or have medical conditions that make you prone to irritation of the stomach and intestines (e.g., Diverticulitis, ulcerative colitis, Crohn's Disease), you should talk to your doctor how Etodolac may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Etodolac, and whether any special monitoring or treatment is needed.
Stop taking the medication and seek immediate medical attention if you develop symptoms of a bleeding ulcer, such as dark tarry stools, blood in the stools, or vomiting up of blood or material that looks like coffee grounds.
Vision changes: Etodolac and other NSAIDs may cause blurred or reduced vision. Stop taking Etodolac if you experience changes in vision and contact your doctor to have an eye examination arranged.
Pregnancy: The safety of using Etodolac during pregnancy has not been established. Etodolac should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Etodolac, contact your doctor immediately.
Breast-feeding: It is not known if etodolac passes into breast milk. If you are a breast-feeding mother and are taking Etodolac, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Etodolac have not been established for children.
Seniors: Seniors who take Etodolac should be closely monitored by their doctors. Seniors may be more likely to develop side effects and may require a lower dose due to decreased kidney and liver function.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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