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Lozide (Indapamide) belongs to the family of medications called diuretics ("water pills"). It is used alone or in combination with other medications to treat mild-to-moderate high blood pressure.
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Lozide (Indapamide) belongs to the family of medications called diuretics ("water pills"). It is used alone or in combination with other medications to treat mild-to-moderate high blood pressure. Lozide (Indapamide) works by making the body lose excess water and salt.
Lozide (Indapamide) may be available under multiple brand names and/or in several different forms. Any specific brand name of Lozide (Indapamide) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Lozide (Indapamide) may not be used for all of the conditions discussed here.
Your doctor may have suggested Lozide (Indapamide) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Lozide (Indapamide), speak to your doctor. Do not stop taking Lozide (Indapamide) without consulting your doctor.
Do not give Lozide (Indapamide) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Lozide (Indapamide) if their doctor has not prescribed it.
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The recommended starting dose of Lozide (Indapamide) is 1.25 mg once daily in the morning. After 4 to 8 weeks, your doctor may increase this to 2.5 mg once daily, depending on the effect of the medication. If a dose of 2.5 mg daily does not reduce your blood pressure sufficiently, your doctor will likely add another blood-pressure-lowering medication that is not a diuretic or may try a different diuretic. Do not take more than 2.5 mg daily.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Lozide (Indapamide) exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Lozide (Indapamide) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Lozide (Indapamide). If you are concerned about side effects, discuss the risks and benefits of Lozide (Indapamide) with your doctor.
The following side effects have been reported by at least 1% of people taking Lozide (Indapamide). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Lozide (Indapamide).
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Each round, orange, film-coated tablet, with "S" marked on one side, contains Lozide (Indapamide) 1.25 mg. Nonmedicinal ingredients: glycerol, hydroxypropyl methylcellulose, lactose monohydrate, macrogol 6000, magnesium stearate, maize starch, microcrystalline cellulose, pregelatinized starch, sunset yellow S Aluminium Lake, talc, and titanium dioxide.
Each pink, sugar-coated tablet contains Lozide (Indapamide) 2.5 mg. Nonmedicinal ingredients: colloidal silica, corn starch, ethylcellulose, FD&C Red No. 3 Lake, FD&C Yellow No. 6 Lake, glycerol monooleate, lactose, magnesium stearate, polysorbate, povidone, pregelatinized corn starch, sodium benzoate, sodium carboxymethylcellulose, sucrose, talc, titanium dioxide, and white beeswax.
Do not take Lozide (Indapamide) if you:
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There may be an interaction between Lozide (Indapamide) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Lozide (Indapamide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Lozide (Indapamide).
Abnormal heart rhythms: Lozide (Indapamide) can cause abnormal heart rhythms. Certain medications (e.g., Sotalol, quinidine, thioridazine, Chlorpromazine, Pimozide, moxifloxacin, Mefloquine, pentamidine, arsenic trioxide, probucol, Tacrolimus) can increase the risk of a type of abnormal heart rhythm called torsades de pointes and should be used with caution with Lozide (Indapamide).
If you are taking medication for abnormal heart rhythms, discuss with your doctor how Lozide (Indapamide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lozide (Indapamide), and whether any special monitoring is needed.
Allergy: Some people who are allergic to sulfonamides also experience allergic reactions to Lozide (Indapamide), as it has a sulfonamide component. Before you take Lozide (Indapamide), tell your doctor about any previous adverse reactions you have had to medications, especially sulfonamide (sulfa) antibiotics. Contact your doctor at once if you experience signs of an allergic reaction, such as skin rash, itching, difficulty breathing, or swelling of the face and throat.
Diabetes: Although Lozide (Indapamide) has very little effect on blood sugar control, people with diabetes may need additional insulin to keep blood sugar levels steady. High blood sugar and sugar in the urine may occur for people who have risk factors for developing diabetes.
If you have diabetes, or are at risk for developing diabetes, discuss with your doctor how Lozide (Indapamide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lozide (Indapamide), and whether any special monitoring is needed.
Dizziness: Lozide (Indapamide) can cause severe dizziness, especially when rising from a sitting or lying position. This is more likely to occur when starting to take Lozide (Indapamide) or increasing the dose being taken, particularly when other medications with similar side effects are being taken. If you are taking medications that can cause dizziness, rise slowly from sitting or lying down to reduce the possibility of severe dizziness or fainting.
Electrolytes: Changes in the blood levels of electrolytes such as potassium and magnesium become severe at doses above 2.5 mg per day. Do not take more than 2.5 mg per day.
Abnormally low blood potassium levels may occur at all doses causing weakness, cramps, and abnormal heart rhythms. The warning signs of electrolyte imbalance are:
Galactose intolerance: Lozide (Indapamide) medications are prepared with lactose. If you have lactose or galactose intolerance you should not take these medications.
Gout: Lozide (Indapamide) may increase the level of uric acid in the body. If you develop painful, warm and swollen joints contact your doctor as soon as possible. If you have a history of gout, discuss with your doctor how Lozide (Indapamide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lozide (Indapamide), and whether any special monitoring is needed.
Kidney function: Lozide (Indapamide) is not helpful for people with severely reduced kidney function. If you have Kidney Disease or reduced kidney function, discuss with your doctor how Lozide (Indapamide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lozide (Indapamide), and whether any special monitoring is needed. If you experience a decrease in the amount of urine your body is producing, contact your doctor as soon as possible.
Liver function: If you have liver disease or reduced liver function, discuss with your doctor how Lozide (Indapamide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lozide (Indapamide), and whether any special monitoring is needed.
If you have severely reduced liver function you should not take Lozide (Indapamide) because this increases the risk for developing liver-caused brain disease.
Sun sensitivity: Like other sulfonamide medications, Lozide (Indapamide) may cause increased sensitivity to the effects of exposure to the sun. If you experience a severe sunburn-like reaction while taking Lozide (Indapamide), contact your doctor immediately. Regardless, you should take measures to protect yourself from the sun, such as use of an appropriate sunscreen and keeping exposed skin covered, while taking Lozide (Indapamide).
Systemic Lupus erythematosus: Lozide (Indapamide) can worsen or activate the symptoms of lupus. If you experience swollen and painful joints, fever, fatigue, or rash on the nose and cheeks while taking Lozide (Indapamide), contact your doctor.
Pregnancy: In general, diuretics should not be used during pregnancy, due to the risk of reducing the growth of the fetus. Lozide (Indapamide) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Lozide (Indapamide), contact your doctor immediately.
Breast-feeding: Lozide (Indapamide) passes into breast milk. If you are a breast-feeding mother and are taking Lozide (Indapamide), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of Lozide (Indapamide) for use by children have not been established.
Seniors: Seniors may be at an increased risk of developing side effects to Lozide (Indapamide). Lower doses may be appropriate when using Lozide (Indapamide) to treat high blood pressure for seniors.
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