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Rasagiline belongs to the family of medications known as monoamine oxidase inhibitors (M. O.
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Rasagiline belongs to the family of medications known as monoamine oxidase inhibitors (M.O.S.. It is used to treat Parkinson's Disease. It acts on the nervous system to increase the levels of a chemical called dopamine. Low dopamine levels in the brain are responsible for many of the symptoms of Parkinson's disease, so Teva Rasagiline works by rebalancing the levels of dopamine.
Teva Rasagiline may be available under multiple brand names and/or in several different forms. Any specific brand name of Teva Rasagiline may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Teva Rasagiline may not be used for all of the conditions discussed here.
Your doctor may have suggested Teva Rasagiline for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Teva Rasagiline, speak to your doctor. Do not stop taking Teva Rasagiline without consulting your doctor.
Do not give Teva Rasagiline to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Teva Rasagiline if their doctor has not prescribed it. Do not stop taking Teva Rasagiline without consulting your doctor.
The recommended dose of rasagiline is 1 mg once daily. The recommended starting dose of rasagiline for someone already taking levodopa is 0.5 mg, which may then be increased to 1 mg once daily if necessary. The recommended starting dose for someone taking a dopamine agonist is 1 mg taken once daily.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
Teva Rasagiline may be taken with or without food.
If you feel you need to stop Teva Rasagiline, contact your doctor for advice on how to discontinue it without causing problems.
It is important that Teva Rasagiline be taken exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Teva Rasagiline at room temperature and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Teva Rasagiline. If you are concerned about side effects, discuss the risks and benefits of Teva Rasagiline with your doctor.
The following side effects have been reported by at least 1% of people taking Teva Rasagiline. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Get medical help immediately if any of the following signs of extremely high blood pressure (caused by the use of Teva Rasagiline with certain foods or other medications) occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Teva Rasagiline.
Each white to off-white, round, flat, bevelled-edged tablet, debossed with "GIL" and "0.5" below on one side and plain on the other, contains 0.5 mg of rasagiline. Nonmedicinal ingredients: colloidal silicon dioxide, mannitol, starch, pregelatinized starch, stearic acid and talc.
Each white to off-white, round, flat, bevelled-edged tablet, debossed with "GIL" and "1" below on one side and plain on the other, contains 1 mg of rasagiline. Nonmedicinal ingredients: colloidal silicon dioxide, mannitol, starch, pregelatinized starch, stearic acid and talc.
Do not take rasagiline if you:
There may be an interaction between rasagiline and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Teva Rasagiline. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Teva Rasagiline.
Antidepressant medication: Severe reactions are possible when rasagiline is combined with medications and natural products used to treat depression. Avoid combining rasagiline and antidepressants. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, and changes in mental state including delirium and agitation. Coma and death are also possible.
If you have taken antidepressants recently, discuss with your doctor how Teva Rasagiline may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Rasagiline, and whether any special monitoring is needed.
Behaviour changes: People taking rasagiline have experienced abnormal behaviour such as compulsive gambling, compulsive shopping, hypersexuality, and binge eating. If you experience these symptoms or any other behaviour change while taking Teva Rasagiline, contact your doctor immediately.
Kidney function: Rasagiline should not be used by people with moderate or severe kidney function impairment. If you have reduced kidney function or Kidney Disease, discuss with your doctor how Teva Rasagiline may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Rasagiline, and whether any special monitoring is needed.
Liver function impairment: Liver disease or reduced liver function may cause Teva Rasagiline to build up in the body, causing side effects. If you have reduced liver function or liver disease, discuss with your doctor how Teva Rasagiline may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Teva Rasagiline, and whether any special monitoring is needed. People with mild liver function impairment may be given 0.5 mg of rasagiline daily. Do not take rasagiline if you have moderate or severe liver function impairment.
Skin Cancer: People taking Teva Rasagiline have a higher risk of developing skin cancer. It is unclear whether this increased risk is due to Parkinson's disease or to rasagiline. You and your doctor should check your skin regularly for signs of skin cancer (e.g., moles that have an irregular shape or border, moles that change colour, or moles that are larger than 6 mm).
Sudden onset of sleep: People taking rasagiline have reported suddenly falling sleep without warning signs of sleepiness or drowsiness. Be careful if driving or operating machinery while taking Teva Rasagiline. If you experience excessive drowsiness or falling asleep suddenly, avoid operating machines or driving and contact your doctor immediately.
Pregnancy: Teva Rasagiline should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Teva Rasagiline, contact your doctor immediately.
Breast-feeding: Rasagiline can reduce the amount of milk produced by a breast-feeding mother. It is not known if rasagiline passes into breast milk. If you are a breast-feeding mother and are taking rasagiline, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Teva Rasagiline have not been established for children.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
December 18, 2023
December 14, 2023
August 8, 2022