M.O.S. (Morphine) belongs to the class of medications called narcotic analgesics (pain relievers). These pain relievers are also known as opioid analgesics. M.O.S. (Morphine) relieves severe pain when less potent pain relievers are not effective. Opioids decrease pain by working on the brain to increase pain tolerance. M.O.S. (Morphine) immediate release works quickly. It will usually relieve pain within about 30 minutes.

M.O.S. (Morphine) may be available under multiple brand names and/or in several different forms. Any specific brand name of M.O.S. (Morphine) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of M.O.S. (Morphine) may not be used for all of the conditions discussed here.

Your doctor may have suggested M.O.S. (Morphine) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking M.O.S. (Morphine), speak to your doctor. Do not stop taking M.O.S. (Morphine) without consulting your doctor.

Do not give M.O.S. (Morphine) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take M.O.S. (Morphine) if their doctor has not prescribed it.

Doses of M.O.S. (Morphine) vary widely and depend on the circumstances of an individual.

After a certain dose of M.O.S. (Morphine) has been taken for a period of time, the body often gets used to it and a higher dose of M.O.S. (Morphine) is needed to relieve the pain. Generally, your doctor will try to find the dose of M.O.S. (Morphine) that will give you acceptable pain relief without an unacceptable level of side effects. This helps to reduce the side effects of the medication and allows for the dose to be adjusted upwards if needed. Always check with your doctor if you feel your medication isn't working well anymore.

Over time, M.O.S. (Morphine) may produce tolerance and physical dependence as your body becomes used to the medication. Tolerance occurs when a dose that used to provide acceptable pain relief is no longer effective, and higher doses are required to achieve the same level of pain relief. Physical dependence is a state where the body will go into withdrawal if the medication is stopped suddenly. If you have been taking M.O.S. (Morphine) on a regular basis for a long period of time, talk to your doctor before stopping the medication, as withdrawal effects can occur.

Tolerance and physical dependence are not the same as addiction. Addiction is defined as a psychological need to use the medication for reasons other than pain relief. Although people may become addicted to M.O.S. (Morphine), it is most common for people who have had addictions to other substances in the past.

M.O.S. (Morphine) tablets should be swallowed whole and not chewed, cut, broken or crushed, which can be dangerous and lead to serious harm or death. M.O.S. (Morphine) capsules should be swallowed whole, or the capsules may be opened and the contents sprinkled on food. The liquid form of M.O.S. (Morphine) may be mixed with a glass of fruit juice just before taking it to improve the taste.

If you are using a suppository, first remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum. If you find the suppository is too soft to insert, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Store M.O.S. (Morphine) at room temperature, protect it from light and moisture, and keep it out of the reach of children. Accidental ingestion of M.O.S. (Morphine), especially by children, can have severe and even fatal consequences.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes M.O.S. (Morphine). If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking M.O.S. (Morphine). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• changes in sexual desire or activity
• confusion
• Constipation (common with long-term use)
• decreased coordination
• dizziness
• difficult or painful urination
• drowsiness
• Dry Mouth
• false sense of well-being
• headache
• lightheadedness or feeling faint
• loss of appetite
• nausea or vomiting
• trouble sleeping
• unusual dreams
• unusual tiredness or weakness

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• blurred or double vision or other changes in vision
• fast, slow, or pounding heartbeat
• Hives, itching, or skin rash
• increased sweating
• shortness of breath, wheezing, or troubled breathing
• symptoms of a bowel blockage (e.g., abdominal pain, severe constipation, nausea)
• withdrawal symptoms (e.g., nausea, vomiting, Diarrhea, anxiety, shivering, cold and clammy skin, body aches, loss of appetite, sweating)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• seizures
• signs of overdose:
  • cold, clammy skin
  • confusion
  • convulsions (seizures)
  • dizziness (severe)
  • drowsiness (severe)
  • Low Blood Pressure
  • nervousness or restlessness (severe)
  • pinpoint-sized pupils of eyes
  • slow heartbeat
  • slow or troubled breathing
  • weakness (severe)
• signs of serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking M.O.S. (Morphine).

Do not take M.O.S. (Morphine) if you:

• are allergic to M.O.S. (Morphine), or any ingredients of the medication
• are allergic to other narcotic analgesics
• are experiencing acute Alcoholism or delirium tremens
• are experiencing acute Asthma or other obstructive airway disease
• are experiencing acute respiratory Depression
• are experiencing mild pain that can be treated with non-narcotic pain relievers
• are taking an MAO inhibitor such as Phenelzine or Tranylcypromine, or have taken one in the past 14 days
• have a blockage of the gastrointestinal tract, particularly paralytic ileus
• have or may have a surgical abdomen (e.g., acute Appendicitis, pancreatis)
• have a head injury, a brain tumour, or increased pressure inside the head or spinal cord
• have abnormal heart rhythms
• have convulsive (seizure) disorders
• have cor pulmonale
• have severe depression of the central nervous system (i.e., sedation)
• have a suspected abdominal condition that may require surgery

There may be an interaction between M.O.S. (Morphine) and any of the following:

• aclidinium
• alcohol
• Aldesleukin
• Aliskiren
• alpha blockers (e.g., Alfuzosin, Doxazosin, Tamsulosin)
• alpha agonists (e.g., Clonidine, methyldopa)
• amphetamines (e.g., Dextroamphetamine, lisdexamphetamine)
• angiotensin-converting enzyme inhibitors (ACEIs; Captopril, Ramipril)
• angiotensin receptor blockers (ARBs; e.g., candasartan, Irbesartan, Losartan)
• antihistamines (e.g., cetirizine, Chlorpheniramine, Dimenhydrinate, Diphenhydramine, Hydroxyzine, Loratadine)
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
• azelastine
• "azole" antifungals (e.g., fluconazole, ketoconazole, Voriconazole)
• barbiturates (e.g., butalbital, pentobarbital, Phenobarbital)
• benzodiazepines (e.g., Alprazolam, Diazepam, Lorazepam)
• Benztropine
• beta-blockers (e.g., Atenolol, Metoprolol, Propranolol)
• brimonidine
• Buprenorphine
• Buspirone
• calcium channel blockers (e.g., Amlodipine, Diltiazem, Nifedipine, Verapamil)
• cannabis
• chloral hydrate
• Clopidogrel
• Cyclosporine
• Desmopressin
• Dextromethorphan
• Dipyridamole
• Disopyramide
• diuretics (water pills; e.g., Furosemide, Hydrochlorothiazide)
• Dronedarone
• efavirenz
• Entacapone
• ergot alkaloids (e.g., ergotamine, Dihydroergotamine)
• Flavoxate
• Guanfacine
• Hydralazine
• ipratropium
• ketotifen
• Lapatinib
• levodopa
• lithium
• Metoclopramide
• Mirtazapine
• monoamine oxidase inhibitors (MAOIs; e.g., Moclobemide, Rasagiline, Selegiline, tranylcypromine) taken within the last 14 days
• muscle relaxants (e.g., Baclofen, Cyclobenzaprine, methocarbamol, orphenadrine)
• Nabilone
• Naltrexone
• other narcotic analgesics (e.g., Codeine, Fentanyl, Meperidine,)
• Octreotide
• Olopatadine
• Oxybutynin
• Pegvisomant
• Pentoxifylline
• phosphodiesterase-5 inhibitors (e.g., Sildenafil, Tadalafil, Vardenafil)
• Pramipexole
• Prasugrel
• quinidine
• quinine
• rifampin
• Ropinirole
• Rotigotine
• St. John's wort
• scopolamine
• seizure medications (e.g., Carbamazepine, Clobazam, Levetiracetam, phenobarbital, Phenytoin, primidone, Topiramate, Valproic acid, zonisamide)
• selective serotonin reuptake inhibitors (SSRIs; e.g., Citalopram, Fluoxetine, Paroxetine, Sertraline)
• serotonin/norepinephrine reuptake inhibitors (SNRIs; e.g., Desvenlafaxine, Duloxetine, Venlafaxine)
• thalidomide
• Ticagrelor
• Ticlopidine
• tiotropium
• tolcapone
• Tolterodine
• tricyclic antidepressants (e.g., Amitriptyline, Imipramine, Nortriptyline)
• "triptan" migraine medications (e.g., Eletriptan, Sumatriptan)
• Tryptophan
• umeclidinium
• Warfarin
• Zolpidem
• Zopiclone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with M.O.S. (Morphine). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.