Estrace

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Available Form:  

TABLET

Manufacturer name:  

Acerus Pharmaceuticals

Generic name:  

ESTRADIOL

Strength:  

0.5MG, 1MG, 2MG

What is Estrace?

Estradiol-17ß (micronized) belongs to the class of medications known as estrogen replacement therapy. Estrogen is a female hormone produced by the ovaries.

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Estrace Price and Cost Calculator

ESTRACE 2MG

ESTRACE 0.5MG

Quantity

Total no. of TABLET(S)

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We accept all insurance plans

Estimated copay

$9.35

Drug cost

$11.75

Dispensing fee

$7.00

Delivery cost

FREE

Insurance coverage

$9.40

**Actual price will depend on the insurance coverage in your province

How much does Estrace cost?

  • The cost of Estrace is $0.39 with us here at PocketPills. The cost of Estrace can be lower if your insurance covers it. To calculate the total price of purchasing Estrace, you should also consider dispensing and delivery fees.

How much is the dispensing fee for Estrace

  • The dispensing cost to order Estrace with us is only $7. Pocketpills aims to offer you the most affordable Estrace price in Canada.
  • Remember, we offer you FREE Shipping in Canada.

Estrace 

Indication

Estradiol-17ß (micronized) belongs to the class of medications known as estrogen replacement therapy. Estrogen is a female hormone produced by the ovaries. Once Menopause is reached, the ovaries produce less estrogen and Progesterone (another hormone), and symptoms of menopause can occur.

Estradiol-17ß (micronized) is an estrogen replacement hormone used to manage menopausal symptoms such as abnormal uterine bleeding, hot flashes, sweating, and chills. (See warnings about duration of use further in this article.)

It may also contribute to the prevention of Osteoporosis in women when combined with diet, calcium, vitamin D, smoking cessation, and exercise. The decision to use Estrace (Estradiol) should be weighed against other options available for the treatment and prevention of osteoporosis.

Women who have not had a hysterectomy must also take a progestogen while they are taking Estrace (Estradiol).

Estrace (Estradiol) may be available under multiple brand names and/or in several different forms. Any specific brand name of Estrace (Estradiol) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Estrace (Estradiol) may not be used for all of the conditions discussed here.

Your doctor may have suggested Estrace (Estradiol) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Estrace (Estradiol), speak to your doctor. Do not stop taking Estrace (Estradiol) without consulting your doctor.

Do not give Estrace (Estradiol) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Estrace (Estradiol) if their doctor has not prescribed it.

Estrace 

Dosage

Typically, estrogen is taken for the first 21 to 25 days of each month. Women who have not had a hysterectomy (i.e., they still have a uterus) should take a progestin (e.g., medroxyprogesterone) for the last 12 to 14 days of each estrogen cycle.

Women who have had a hysterectomy may take estrogen daily, without a break.

For treatment of menopausal symptoms, the usual dose is 1 mg daily for 21 to 25 days of each month. Attempts to discontinue the medication should be made every 3 to 6 months. If symptoms return, the medication should be continued.

For prevention of osteoporosis, the usual dose is 0.5 mg daily as soon as possible after the onset of menopause. The dose may be increased or decreased according to the level of Estrace (Estradiol) in the blood.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Estrace (Estradiol) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Estrace 

Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of Estrace (Estradiol) with your doctor.

The following side effects have been reported by at least 1% of people taking Estrace (Estradiol). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • Acne
  • bloating of stomach
  • breast pain or swelling
  • changes in cholesterol levels
  • dizziness
  • hair loss
  • headache (mild)
  • irritability
  • nausea
  • stomach cramps
  • vaginal itching, discharge, or pain
  • vomiting
  • weight changes

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • blood pressure changes
  • breast lumps or discharge
  • groin pain
  • nervousness
  • rash
  • signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
  • signs of liver problems (e.g., nausea, vomiting, Diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
  • unexpected vaginal bleeding

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of a blood clot in the arm or leg (tenderness, pain, swelling, warmth, or redness in the arm or leg) or lungs (difficulty breathing, sharp chest pain that is worst when breathing in, coughing, coughing up blood, sweating, or passing out)
  • signs of Heart Attack (e.g., sudden chest pain or pain radiating to back, down arm, jaw; sensation of fullness of the chest; nausea; vomiting; sweating; anxiety)
  • signs of stroke (e.g., sudden or severe headache; sudden loss of coordination; vision changes; sudden slurring of speech; or unexplained weakness, numbness, or pain in arm or leg)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Estrace (Estradiol)

Estrace 

Available form

0.5 mg
Each white, round, flat-faced, bevel-edged compressed tablet, with MJ logo and "021" on one side and scored on the reverse, contains estradiol-17ß (micronized) 0.5 mg. Nonmedicinal ingredients: acacia, dibasic calcium phosphate, cornstarch, lactose, magnesium stearate, silicon dioxide, and talc.

1 mg
Each lavender, round, flat-faced, bevel-edged compressed tablet, with MJ logo and "755" on one side and scored on the reverse, contains estradiol-17ß (micronized) 1 mg. Nonmedicinal ingredients: acacia, dibasic calcium phosphate, cornstarch, D&C Red No. 27 Aluminum Lake, FD&C Blue No. 1 Aluminum Lake, lactose, magnesium stearate, silicon dioxide, and talc.

2 mg
Each turquoise, round, flat-faced, bevel-edged compressed tablet, with MJ logo and "756" on one side and scored on the reverse, contains estradiol-17ß (micronized) 2 mg. Nonmedicinal ingredients: acacia, dibasic calcium phosphate, cornstarch, FD&C Blue No. 1 Aluminum Lake, FD&C Yellow No. 5 Aluminum Lake (tartrazine), lactose, magnesium stearate, silicon dioxide, and talc.

Estrace 

Contraindications

Do not take estradiol-17ß (micronized) if you:

  • are allergic to any ingredients of the medication
  • are breast-feeding
  • are or may be pregnant
  • have a known or suspected estrogen-dependent tumour
  • have endometrial hyperplasia (thickening of the lining of the uterus)
  • have had a blockage in an artery feeding the heart caused by a blood clot (coronary thrombosis)
  • have had a Stroke
  • have had diseases of circulation or clotting
  • have migraine Headaches
  • have had partial or complete loss of vision or double-vision from eye disease related to circulation problems
  • have liver impairment or disease, especially of the obstructive type
  • have or have had Breast Cancer or endometrial cancer, except in special circumstances
  • have undiagnosed vaginal bleeding

Estrace 

Precautions

There may be an interaction between Estrace (Estradiol) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Estrace 

Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Estrace (Estradiol).

Important information about estrogen:

The Women's Health Initiative (WHI) study results indicated an increased risk of heart attack, stroke, breast cancer, Blood Clots in the lungs, and blood clots in the leg veins in postmenopausal women during 5 years of treatment with 0.625 mg conjugated equine estrogens and 2.5 mg medroxyprogesterone compared to women receiving sugar tablets.

  • Estrace (Estradiol) should be used at the lowest dose that relieves your menopausal symptoms for the shortest time period possible.
  • You should not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes.

Blood clotting disorders: Estrogens should not be used if you have active Thrombophlebitis or a thromboembolic disorder (diseases of blood clotting and abnormal circulation). They should also not be used (except in the treatment of cancer) if you have a history of a clotting disorder that is  likely to be caused by estrogen use. Finally, they should be used with caution if you have any  cerebral vascular disease or Coronary Artery Disease, and then, only used if clearly needed.

Some studies have suggested that there is an increased relative risk for healthy women to develop deep vein thrombosis or pulmonary Embolism when they use hormone replacement therapy. Women with severe Varicose Veins or severe Obesity, and those needing to stay in bed for 3 weeks or more, are generally considered to be at increased risk of venous thromboembolism (blood clots in the bloodstream).

Blood pressure: There have been reports of increased blood pressure in women taking Estrace (Estradiol). Your doctor should monitor your blood pressure if you are using estrogen, especially if high doses are used. Regular checkups by your doctor are recommended. If you have high blood pressure, discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Breast cancer: Studies indicate an increased risk of breast cancer with long-term use of estrogen replacement therapy. If you have have breast nodules, fibrocystic disease, abnormal mammograms, or a strong family history of breast cancer, discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Estrace (Estradiol), and whether any special monitoring is needed. Women who take estrogens should have regular breast examinations and should be instructed in breast self-examination.

Cholesterol: Oral estrogens can increase triglycerides in the blood. If you have high blood cholesterol levels, discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Estrace (Estradiol), and whether any special monitoring is needed.

Dementia: Women over age 65 receiving estrogen, with or without a progestin may be at increased risk of developing dementia (loss of memory and intellectual function). If you are over 65 years of age, your doctor should closely monitor you for loss of memory and intellectual function.

Diabetes: Estrogens can cause changes in blood glucose control for people who have diabetes or have risk factors for developing diabetes. If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Estrace (Estradiol), and whether any special monitoring is needed.

People who have diabetes (or a predisposition to diabetes) should monitor their blood glucose levels closely to detect changes in blood glucose.

Endometrial cancer: There is evidence from several studies that estrogen replacement therapy increases the risk of cancer of the endometrium (uterus). Taking a progestin appropriately along with the estrogen reduces this risk to the same level as that of a woman who does not take estrogen. For this reason, all women who have not had their uterus removed should also take progestin if they use estrogens.

Fibroids: Estrace (Estradiol) may worsen fibroids, causing sudden enlargement, pain, or tenderness. If you notice these effects, contact your doctor.

Fluid retention: Estrogen may cause sodium (salt) and fluid retention. This can be dangerous for women with heart or kidney dysfunction, Epilepsy, or Asthma. If you have any of these conditions, discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Estrace (Estradiol), and whether any special monitoring is needed.

If you notice the symptoms of any of these conditions getting worse, contact your doctor.

Gallbladder disease: An increased risk of gallbladder disease has been reported in postmenopausal women who take estrogens. If you have a history of gallbladder disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Estrace (Estradiol), and whether any special monitoring is needed.

If you experience symptoms of gallbladder disease, such as abdominal pain, possibly with Fever and chills, contact your doctor as soon as possible.

Heart disease and stroke: Studies indicate an increased risk of heart disease and stroke with estrogen (with or without progestins) for postmenopausal women. If you experience symptoms of a heart attack (chest pain, tightness or pressure, sweating, nausea, feeling of impending doom) or stroke (sudden dizziness, headache, loss of speech, changes in vision, weakness or numbness in the arms and legs) while taking Estrace (Estradiol), get immediate medical attention.

Liver function: If you have or have had liver problems, you may require special monitoring by your doctor while you use Estrace (Estradiol). Make sure to tell your doctor if you have ever had liver problems.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Migraine: People who are at risk of experiencing migraine may have an increased risk of stroke when taking conjugated estrogens. If you have migraine with aura, discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Estrace (Estradiol), and whether any special monitoring is needed.

Ovarian Cancer: Recent studies have linked long term use of estrogen with an increased risk of ovarian cancer. This increased risk appears to occur whether estrogen is used with a progestin or alone. Discuss the risks and benefits of prolonged use of hormone replacement therapy with your doctor.

Seizures: Hormone replacement therapy may increase the frequency of seizures for people with a history of seizure disorder. If you have a history of seizures, discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Estrace (Estradiol), and whether any special monitoring is needed.

Thyroid conditions: Estrogens can increase the amount of thyroid hormone your body needs to work properly. If you are hypothyroid (have reduced amount of thyroid hormone in your body) and need estrogens, you may require an increased amount of thyroid hormone for your body to continue to work properly. Discuss with your doctor how Estrace (Estradiol) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Pregnancy: Estrogen should not be used during pregnancy. If you become pregnant while taking Estrace (Estradiol), contact your doctor.

Breast-feeding: Estrogen is not safe for use during breast-feeding. A decision should be made whether to discontinue breast-feeding or to discontinue the medication, taking into account the importance of the medication to the mother.

Children: The safety and effectiveness of Estrace (Estradiol) have not been established for children.

Estrace frequently asked questions

How To Buy Estrace Online?

You can buy Estrace online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Estrace?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Estrace in Canada?

Shipping cost for Estrace to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

How to get Estrace delivered to my home?

You could get Estrace delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Estrace in Canada for free?

You can get Estrace for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Estrace for free.

Can I consult a doctor online to get Estrace?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Estrace.

Can I buy Estrace without a prescription?

You need a valid prescription to buy Estrace from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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