Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Bricanyl Turbuhaler (Terbutaline-inh). If you are concerned about side effects, discuss the risks and benefits of Bricanyl Turbuhaler (Terbutaline-inh) with your doctor.

The following side effects have been reported by at least 1% of people taking Bricanyl Turbuhaler (Terbutaline-inh). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• coughing
• dizziness
• drowsiness
• dryness or irritation of mouth or throat
• flushing
• headache
• hyperactivity
• increased heart rate
• muscle cramps
• nausea
• nervousness
• rash
• shakiness
• sweating
• tremor
• trouble sleeping
• upset stomach
• vomiting
• weakness

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• agitation
• chest pain
• heart palpitations (irregular or fast heartbeat, usually felt as a rapid thumping in the chest)
• restlessness
• signs of low potassium levels in the blood (e.g., weakness, fatigue, muscle cramps, irregular heartbeat)

Stop taking the medication and seek immediate medical attention if any of the following occur:

• bronchospasm – difficulty breathing immediately after using the medication
• symptoms of a serious allergic reaction, e.g.:
• difficulty breathing
• Hives
• swelling of the face or throat

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Bricanyl Turbuhaler (Terbutaline-inh).

Each Turbuhaler contains 50 or 200 doses of micronized terbutaline sulfate. Each inhalation from the multiple-dose powder inhaler contains terbutaline sulfate 0.5 mg. No additives or carrier substances are included in the inhalation.

Do not use Bricanyl Turbuhaler (Terbutaline-inh) if you:

• are allergic to terbutaline or any ingredients of Bricanyl Turbuhaler (Terbutaline-inh)
• are allergic to other sympathomimetic amines (e.g., salbutamol, formoterol)
• are using Bricanyl Turbuhaler (Terbutaline-inh) to prevent premature labour or threatened abortion
• have abnormal heart rhythms associated with fast heart rate

There may be an interaction between terbutaline and any of the following:

• Alfuzosin
• Amiodarone
• amphetamines (e.g., Dextroamphetamine, Lisdexamfetamine)
• antipsychotics (e.g., Chlorpromazine, Clozapine, Haloperidol, Olanzapine, Quetiapine, Risperidone)
• Atomoxetine
• beta-blocker medications (e.g., Propranolol, Metoprolol)
• Betahistine
• caffeine
• cannabis
• certain kinase inhbitors (e.g., Lapatinib, Pazopanib, Sunitinib)
• chloroquine
• Citalopram
• decongestant cold medications (e.g., phenylephrine, Pseudoephedrine)
• decongestant eye drops and nose sprays (e.g., naphazoline, oxymetazoline, xylometazoline)
• Degarelix
• dipiverin
• Disopyramide
• diuretics (e.g., bumetanide, Furosemide, Hydrochlorothiazide, Metolazone)
• dofetilide
• Domperidone
• dopamine
• Dronedarone
• Epinephrine
• Flecainide
• Linezolid
• long-acting bronchodilators (e.g., formoterol, salmeterol)
• macrolide antibiotics (e.g., clarithromycin, erythromycin)
• Methadone
• Methylphenidate
• mifepristone
• MAO inhibitors (e.g., Phenelzine, Tranylcypromine)
• Nabilone
• other fast-acting bronchodilators (e.g., Indacaterol, salbutamol)
• Pimozide
• procainamide
• quinidine
• quinine
• quinolone antibiotics (e.g., ciprofloxacin, Ofloxacin, sparfloxacin)
• rilpivirine
• saquinavir
• serotonin antagonists (anti-emetic medications; e.g., Granisetron, Ondansetron)
• Sotalol
• Tetrabenazine
• theophyllines (e.g., Aminophylline, Oxtriphylline, Theophylline)
• Trazodone
• Voriconazole
• tricyclic antidepressants (e.g., Amitriptyline, Desipramine)

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Bricanyl Turbuhaler (Terbutaline-inh). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Bricanyl Turbuhaler (Terbutaline-inh).

Appropriate use of the medication: Terbutaline should not be used on a regular daily basis without appropriate regular daily use of an inhaled anti-inflammatory medication (e.g., budesonide, beclomethasone, fluticasone, triamcinolone).

Diabetes: Terbutaline may cause an increase in blood sugar levels (may cause a loss of blood glucose control) and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Bricanyl Turbuhaler (Terbutaline-inh).

If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Bricanyl Turbuhaler (Terbutaline-inh) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bricanyl Turbuhaler (Terbutaline-inh), and whether any special monitoring is needed.

Heart rhythm: Beta-agonists such as terbutaline can cause changes to the normal rhythm of the heart. If you are at risk for heart rhythm problems (e.g., people with heart failure, Angina, low potassium or magnesium levels), discuss with your doctor how Bricanyl Turbuhaler (Terbutaline-inh) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bricanyl Turbuhaler (Terbutaline-inh), and whether any special monitoring is needed.

Inhalation-induced bronchospasm: Inhaled forms of medications may cause spasms of the airways, which make breathing difficult. If you experience this problem when using terbutaline, stop using Bricanyl Turbuhaler (Terbutaline-inh) immediately. Speak to your doctor if you experience any problems with breathing while taking this or other inhaled medication.

Proper use of device: To ensure you receive the proper dosage from your inhaler, ask your doctor, pharmacist, or other health professional to instruct you on its use.

Seizures: If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how Bricanyl Turbuhaler (Terbutaline-inh) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bricanyl Turbuhaler (Terbutaline-inh), and whether any special monitoring is needed.

Thyroid disease: People with an overactive thyroid gland may be more sensitive to the effects of terbutaline. If you have thyroid disease, discuss with your doctor how Bricanyl Turbuhaler (Terbutaline-inh) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Bricanyl Turbuhaler (Terbutaline-inh), and whether any special monitoring is needed.

Worsening of symptoms: If your symptoms don't improve or seem to get worse, check with your doctor. You may need a new plan for treatment. Contact a doctor immediately if you have acute or suddenly worsening shortness of breath. Increasing use of Bricanyl Turbuhaler (Terbutaline-inh) to control symptoms, especially on a regular basis or in high amounts, indicates a worsening of asthma control. Under these conditions, your treatment plan needs to be changed. It is not enough simply to increase the use of terbutaline under these circumstances, particularly over extended periods of time.

Pregnancy: Bricanyl Turbuhaler (Terbutaline-inh) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Bricanyl Turbuhaler (Terbutaline-inh), contact your doctor immediately.

Breast-feeding: Bricanyl Turbuhaler (Terbutaline-inh) passes into breast milk. If you are a breast-feeding mother and are taking terbutaline, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Bricanyl Turbuhaler (Terbutaline-inh) have not been established for children less than 6 years of age.