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Trazorel (Trazodone) belongs to the class of medications called antidepressants. It is used to treat symptoms of Depression.
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Trazorel (Trazodone) belongs to the class of medications called antidepressants. It is used to treat symptoms of Depression. It works by affecting the balance of chemicals in the brain that are associated with depression. It may take up to 4 weeks before the full beneficial effects of Trazorel (Trazodone) are seen.
Trazorel (Trazodone) may be available under multiple brand names and/or in several different forms. Any specific brand name of Trazorel (Trazodone) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Trazorel (Trazodone) may not be used for all of the conditions discussed here.
Your doctor may have suggested Trazorel (Trazodone) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Trazorel (Trazodone), speak to your doctor. Do not stop taking Trazorel (Trazodone) without consulting your doctor.
Do not give Trazorel (Trazodone) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Trazorel (Trazodone) if their doctor has not prescribed it.
The recommended adult dose of Trazorel (Trazodone) ranges from 150 mg to 300 mg daily, taken in 2 or 3 divided doses with a meal or light snack.
The dose is usually started at 150 mg to 200 mg daily and increased gradually until the best dose is found.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important that Trazorel (Trazodone) be taken exactly as prescribed by your doctor. If you miss a dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Trazorel (Trazodone) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Trazorel (Trazodone). If you are concerned about side effects, discuss the risks and benefits of Trazorel (Trazodone) with your doctor.
The following side effects have been reported by at least 1% of people taking Trazorel (Trazodone). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Trazorel (Trazodone).
Trazorel is no longer being manufactured for sale in Canada. For brands that may still be available, search under Trazorel (Trazodone). This article is being kept available for reference purposes only. If you are using Trazorel (Trazodone), speak with your doctor or pharmacist for information about your treatment options.
Do not take Trazorel (Trazodone) if you are allergic to Trazorel (Trazodone) or any ingredients of the medication.
There may be an interaction between Trazorel (Trazodone) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Trazorel (Trazodone). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Trazorel (Trazodone).
Behaviour changes and suicidal thoughts: Trazorel (Trazodone) may worsen symptoms of depression, including thoughts of suicide or wanting to harm themselves or others. It may also cause agitated or aggressive behaviour. If you experience these symptoms or any other behaviour change while taking Trazorel (Trazodone), contact your doctor immediately. Family members or caregivers of people who are taking Trazorel (Trazodone) should contact the person's doctor immediately if they notice unusual behaviour changes.
Bleeding: Trazorel (Trazodone) may cause a reduced number of platelets in the blood, which can make it difficult to stop cuts from bleeding. If you notice any signs of bleeding, such as frequent nosebleeds, unexplained bruising, or black and tarry stools, notify your doctor as soon as possible. Your doctor will order routine blood tests to make sure potential problems are caught early.
Glaucoma: Trazorel (Trazodone) may worsen symptoms of glaucoma (increased pressure in the eyes), such as blurred vision or eye pain or pressure. If you have glaucoma, discuss with your doctor how Trazorel (Trazodone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trazorel (Trazodone), and whether any special monitoring is needed.
Heart rhythm: Trazorel (Trazodone) can cause changes to the normal rhythm of the heart, including an irregular heartbeat called QT prolongation. QT prolongation is a serious life-threatening condition that can cause fainting, seizures, and sudden death. If you are at risk for heart rhythm problems (e.g., people with heart failure, Angina, low potassium or magnesium levels), discuss with your doctor how Trazorel (Trazodone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trazorel (Trazodone), and whether any special monitoring is needed.
Blood pressure: Trazorel (Trazodone) may cause Low Blood Pressure and possibly cause a feeling of lightheadedness when moving from a sitting or lying position to a standing position.
Dizziness: Trazorel (Trazodone) can cause severe dizziness, especially when rising from a sitting or lying position. People taking medications that can cause dizziness should rise slowly from sitting or lying down to reduce the possibility of severe dizziness or fainting.
Drowsiness/reduced alertness: Trazorel (Trazodone) may impair the mental or physical abilities required for potentially hazardous tasks, such as driving or operating machinery. Avoid driving, operating machinery, or performing other hazardous tasks until you have determined how Trazorel (Trazodone) affects you.
Priapism: Trazorel (Trazodone) has been associated with prolonged or inappropriate erections (priapism) for a number of men taking Trazorel (Trazodone). If this occurs, stop taking the medication immediately and contact your doctor.
Seizures: Seizures have been reported for a small number of people taking Trazorel (Trazodone). Most of these people were already taking medications for a previously diagnosed seizure disorder. If you have a history of seizures, discuss with your doctor how Trazorel (Trazodone) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Trazorel (Trazodone), and whether any special monitoring is needed.
Serotonin syndrome: Rarely, severe, life-threatening reactions are possible when Trazorel (Trazodone) is combined with other medications that act on serotonin, such as tricyclic antidepressants and serotonin reuptake inhibitors, which are other medications used to treat depression. This is called serotonin syndrome. These combinations should be avoided. Symptoms of a reaction may include muscle rigidity and spasms, difficulty moving, changes in mental state including delirium and agitation. Coma and death are possible.
Stopping the medication: If Trazorel (Trazodone) needs to be stopped, it should be done gradually, under the supervision of your doctor. Suddenly stopping Trazorel (Trazodone) can cause anxiety, agitation or sleep problems.
Pregnancy: The safety of Trazorel (Trazodone) for use during pregnancy has not been established. It should not be used by women who may become pregnant unless, in the opinion of their doctor, the expected benefits outweigh the potential risks. If you are or may be pregnant, talk to your doctor about the risks and benefits of Trazorel (Trazodone).
Breast-feeding: It is not known if Trazorel (Trazodone) passes into breast milk. If you are a breast-feeding mother and are taking Trazorel (Trazodone), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children and adolescents: The safety and effectiveness of Trazorel (Trazodone) have not been established for people less than 18 years of age.
Seniors: People over the age of 65 years may be more at risk of side effects from Trazorel (Trazodone) and may require lower treatment doses.
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