Pimozide

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Available Form:  

TABLET

Manufacturer name:  

Aa Pharma

Generic name:  

PIMOZIDE

Strength:  

2MG

What is Pimozide?

Pimozide belongs to the class of medications called antipsychotics. It is used to manage symptoms of certain types of chronic Schizophrenia.

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How much does Pimozide cost?

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Pimozide 

Indication

Pimozide belongs to the class of medications called antipsychotics. It is used to manage symptoms of certain types of chronic Schizophrenia. It works by affecting the way messages are sent in the central nervous system.

Pimozide may be available under multiple brand names and/or in several different forms. Any specific brand name of Pimozide may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Pimozide may not be used for all of the conditions discussed here.

Your doctor may have suggested Pimozide for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Pimozide, speak to your doctor. Do not stop taking Pimozide without consulting your doctor.

Do not give Pimozide to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Pimozide if their doctor has not prescribed it.

Pimozide 

Dosage

Adults: The recommended starting dose of pimozide ranges from 2 mg to 4 mg once daily, taken in the morning. Your doctor will gradually increase your dose to a maximum of 20 mg daily. The goal is to find the dose where the best effects occur with the least side effects.

Seniors: The recommended starting dose of pimozide ranges from 1 mg to 2 mg once daily, taken in the morning. Your doctor will gradually increase your dose to a maximum of 20 mg daily. The goal is to find the dose where the best effects occur with the least side effects.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Pimozide exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Pimozide 

Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes Pimozide. If you are concerned about side effects, discuss the risks and benefits of Pimozide with your doctor.

The following side effects have been reported by at least 1% of people taking Pimozide. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • Constipation
  • decreased interest in sexual activity
  • decreased sweating
  • difficulty holding urine
  • dizziness
  • drowsiness
  • Dry Mouth
  • fatigue
  • lightheadedness, or fainting when rising from a lying or sitting position
  • menstrual changes
  • sinus congestion
  • weight changes

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • blurred vision or other vision problems
  • confusion
  • excessive sweating
  • fast or irregular heartbeat
  • inability to move eyes
  • increased blinking or eyelid spasms
  • lack of facial expression
  • lip smacking or puckering
  • loss of balance control
  • mood or behaviour changes
  • movement disorders (e.g., continuous muscle spasms and contractions, slow movements, irregular, jerky movements, tremor, inability to move eyes, increased blinking, puffing of cheeks, shuffling walk, tremor)
  • restlessness or need to keep moving
  • signs of a blood clot in the arm or leg (tenderness, pain, swelling, warmth, or redness in the arm or leg) or lungs (difficulty breathing, sharp chest pain that is worst when breathing in, coughing, coughing up blood, sweating, or passing out)
  • signs of liver problems (e.g., nausea, vomiting, Diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • swelling or soreness of breasts (less common in men)
  • symptoms of high blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
  • symptoms of a lung infection (LRTI) (e.g., shortness of breath, cough, chest pain)
  • uncontrolled chewing movements or uncontrolled movements of the neck, trunk, arms, or legs, including twisting movements
  • unusual secretion of milk (rare in men)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • convulsions (seizures)
  • long-lasting (greater than 4 hours) and painful erection of the penis
  • loss of consciousness (fainting)
  • high or low (irregular) blood pressure
  • signs of neuroleptic malignant syndrome (e.g., confusion, reduced consciousness, high Fever, or muscle stiffness)
  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Pimozide.

Pimozide 

Available form

2 mg
Each round, white, flat-faced, bevelled-edge, scored tablet, engraved "PIM" over "2" on one side, contains pimozide 2 mg. Nonmedicinal ingredients: anhydrous lactose, croscarmellose sodium, and magnesium stearate.

4 mg
Each round, light green, flat-faced, bevelled-edge, scored tablet, engraved "PIM" over "4" on  one side, contains pimozide 4 mg. Nonmedicinal ingredients: anhydrous lactose, croscarmellose sodium, D&C Yellow No. 10 Aluminum Lake, FD&C Blue No. 2 Aluminum Lake, and magnesium stearate.

Pimozide 

Contraindications

Do not take pimozide if you:

  • are allergic to pimozide or to any of the ingredients of the medication
  • are sedated or unconscious
  • have brain damage
  • are taking any of the classes of medications known as "azole" antifungals, antiviral protease inhibitors, or macrolide antibiotics (erythromycins)
  • are taking Sertraline, Citalopram, Escitalopram, or Paroxetine
  • are treating tics other than those caused by Tourette’s Disorder
  • have Depression
  • have or have a family history of certain types of abnormal heart rhythms
  • have a severely reduced heart rate
  • have a blood disorder
  • have a liver disorder
  • have low blood potassium or magnesium levels
  • have Parkinson's Disease
  • have reduced kidney function
  • are scheduled for regional or spinal anaesthetic

Pimozide 

Precautions

There may be an interaction between pimozide and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Pimozide. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Pimozide 

Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Pimozide.

Abnormal heart rhythms: Pimozide can cause abnormal heart rhythms. Certain medications can increase the risk of a type of abnormal heart rhythm called QT prolongation, and should not be used in combination with pimozide. You are more at risk for this type of abnormal heart rhythm and its complications if you:

  • are female
  • are older than 65 years of age
  • have a family history of sudden cardiac death
  • have a history of heart disease or abnormal heart rhythms
  • have a slow heart rate
  • have congenital prolongation of the QT interval
  • have Diabetes
  • have had a Stroke
  • have low potassium, magnesium, or calcium levels
  • have nutritional deficiencies

If you have heart disease and abnormal heart rhythms, or are taking certain medications (e.g., ketoconazole, atazanavir), discuss with your doctor how Pimozide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pimozide, and whether any special monitoring is needed.

Blood counts: Pimozide can decrease the number of neutrophils (a type of white blood cell that helps fight infection), red blood cells (which carry oxygen), and platelets (which help your blood to clot). Your doctor will do blood tests to monitor this. If you notice any signs of infection (e.g., fever, chills, or sore throat) or unusual bleeding or bruising, contact your doctor immediately.

Blood pressure: People who take pimozide may develop very Low Blood Pressure causing dizziness and lightheadedness. Some individuals, especially seniors or those who are debilitated, have had temporary low blood pressure for several hours after taking the medication.

Body temperature: Pimozide, like other antipsychotic medications, may interfere with your body's ability to regulate body temperature. People who exercise vigorously, who are exposed to extreme heat, are dehydrated, or are taking anticholinergic medications (e.g., Benztropine, Oxybutynin) are more at risk. Contact your doctor as soon as possible if you feel very hot and are unable to cool down.

Take care to avoid overheating during strenuous exercise or in hot temperatures, and avoid becoming dehydrated by drinking enough fluids.

Diabetes: Pimozide may cause an increase in blood sugar levels (may cause a loss of blood glucose control) and glucose tolerance may change. People with diabetes may find it necessary to monitor their blood sugar more frequently while using Pimozide.

If you have diabetes or are at risk for developing diabetes, discuss with your doctor how Pimozide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pimozide, and whether any special monitoring is needed.

Drowsiness/reduced alertness: Pimozide may reduce alertness, especially at the start of treatment. Alcohol may increase this effect. Avoid tasks requiring alertness, such as driving or operating machinery, until you determine if the medication affects you this way.

Grapefruit juice: Grapefruit juice prevents pimozide from being broken down (metabolized) in the body and may cause an increase in side effects. Avoid drinking grapefruit juice if you take pimozide.

Liver function: Liver disease or reduced liver function may cause Pimozide to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Pimozide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pimozide, and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Pimozide.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Neuroleptic malignant syndrome (NMS): Pimozide, like other antipsychotic medications, can cause a potentially fatal syndrome known as neuroleptic malignant syndrome (NMS). If you notice the symptoms of NMS such as high fever, muscle stiffness, confusion or loss of consciousness, sweating, racing or irregular heartbeat, or fainting, get immediate medical attention.

Seizures: Pimozide may increase the risk of seizures. If you have a history of Epilepsy or medical conditions that increase the risk of seizures, discuss with your doctor how Pimozide may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Pimozide, and whether any special monitoring is needed.

Stopping the medication: Do not stop taking Pimozide without speaking to your doctor. Stopping suddenly may lead to uncomfortable side effects, such as nausea, vomiting, difficulty sleeping, or unwanted movement. Your doctor may wish to gradually reduce your dose over time.

Tardive dyskinesia (TD): As with all antipsychotic medications, a syndrome called TD may occur for some people on long-term therapy or after they stop taking the medication. The syndrome's main features are rhythmical involuntary movements of the tongue, face, mouth, or jaw. Tell the doctor if you notice these symptoms in yourself or someone else taking pimozide.

Pregnancy: The safe of use of pimozide during pregnancy has not been established. It should not be taken by women who are or may become pregnant, particularly during the first trimester of pregnancy, unless the benefits outweigh the risks.

Breast-feeding: Pimozide may pass into breast milk. If you are a breast-feeding mother and are taking pimozide, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Pimozide have not been established for children. Pimozide is not recommended for children.

Seniors: When used to treat seniors with Dementia, other antipsychotic medications have shown an increase in the risk of death as a result of Heart Attack, stroke, or infection. Pimozide should not be used to treat seniors with dementia.

Pimozide frequently asked questions

How To Buy Pimozide Online?

You can buy Pimozide online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Pimozide?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Pimozide in Canada?

Shipping cost for Pimozide to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

How to get Pimozide delivered to my home?

You could get Pimozide delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Pimozide in Canada for free?

You can get Pimozide for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Pimozide for free.

Can I consult a doctor online to get Pimozide?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Pimozide.

Can I buy Pimozide without a prescription?

You need a valid prescription to buy Pimozide from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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