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Lucentis

Lucentis

Ranibizumab

Lucentis (Ranibizumab) belongs to the class of medications called antivascular endothelial growth factors. It is used to treat "wet," age-related Macular Degeneration, a condition where blood vessels behind the Retin A start to grow and leak blood and fluid.

Available form

Injectable

Dosage

2.3mg/0.23ml

Manufacturers

Biogen, Novartis Pharmaceuticals, Teva

Generic brand of

Ranibizumab

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Lucentis information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

Lucentis (Ranibizumab) is given by your doctor (usually an eye doctor) via injection into the eye under a local anesthetic.

For "wet" age-related macular edema, the usual dose of Lucentis (Ranibizumab) is 0.5 mg injected into the eye once a month. Injections may be given every 3 months after the first 3 injections, if monthly injections are not possible. However, monthly dosing appears to produce a better response.

For loss of vision because of diabetes or blockage of the retinal vein, the usual dose of Lucentis (Ranibizumab) is 0.5 mg injected into the eye once a month. Your doctor will determine how long treatments should continue depending on your response to treatment.

For pathological myopia, the usual dose of Lucentis (Ranibizumab) is a single injection of 0.5 mg. Your doctor will monitor your vision to determine if any further treatment is needed.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are receiving the medication without consulting your doctor.

Your doctor will ask you to use antibiotic eye drops for a few days before and after each injection.

It is important Lucentis (Ranibizumab) be given exactly as recommended by your doctor. If you miss an appointment to receive Lucentis (Ranibizumab), contact your doctor as soon as possible to reschedule your appointment.

Lucentis (Ranibizumab) is stored in the refrigerator and should not be allowed to freeze. It may be stored at room temperature for up to 24 hours before injection. It should be protected from light and kept out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Lucentis (Ranibizumab). If you are concerned about side effects, discuss the risks and benefits of Lucentis (Ranibizumab) with your doctor.

The following side effects have been reported by at least 1% of people taking Lucentis (Ranibizumab). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

anxiety
back pain
bloodshot eye
Diarrhea
dry eye
eye discharge
eye irritation, itching, or discomfort
eyelid swelling or pain
fatigue
feeling of fullness or tightness in the nose, cheeks, and behind the eyes (sometimes throbbing)
feeling of having something in the eye
flu-like symptoms
headache
increased blood pressure
increased tear production
joint pain
light sensitivity
nausea
reaction at the injection site (e.g., irritation, itching, swelling)
skin itching
temporary blurred vision or vision changes

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

abnormal heart rhythms
cloudiness of the lens of the eye
increased pressure in the eye
pain or redness in the eye
persistent blurred vision or vision changes
small particles or spots in vision
symptoms of an eye infection such as eye discharge, redness, or inflammation
symptoms of an infection of the lower airways such as Fever and cough
symptoms of Anemia (low red blood cells) such as shortness of breath and tiredness

Stop taking the medication and seek immediate medical attention if any of the following occur:

blindness
eye bleeding
signs of a blood clot in the leg (deep vein thrombosis or DVT) such as sudden pain in the large muscle of the leg, or warmth and swelling of the lower part of one leg
symptoms of a Anaphylaxis (severe allergic reaction) such as difficulty breathing; Hives; or swelling of the face, mouth, throat, or tongue
symptoms of a Stroke (e.g., sudden blurred vision, speech difficulty, dizziness, or difficulty moving limbs on one side of the body)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Lucentis (Ranibizumab).

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Lucentis (Ranibizumab).

Blood clotting: Treatment with Lucentis (Ranibizumab) should be stopped for people who develop clots that block their blood vessels. Tell your doctor if you have a history of clotting or are over 65 years of age, as you may be at increased risk of experiencing blood clot-related problems such as Heart Attack, stroke, or clots in the deep veins of your leg. People with any of these conditions should discuss with their doctor, how Lucentis (Ranibizumab) may affect their medical condition, how their medical condition may affect the dosing and effectiveness of Lucentis (Ranibizumab), and whether any special monitoring is needed.

Driving and using machines: Lucentis (Ranibizumab) may cause short term blurred vision, affecting your ability to drive or operate machinery. Avoid these and other hazardous tasks until your vision is clear.

Eye problems: Lucentis (Ranibizumab) can cause eye problems such as infection of the inside part of the eye, pain or redness, detachment or tear of the retina, or clouding of the lens. If you experience eye pain, increased eye discomfort, worsening eye redness, blurred or reduced vision, increased sensitivity of the eyes to light, or an increase in the number of small particles in your vision, contact your doctor immediately.

Increased eye pressure: Lucentis (Ranibizumab) can increase the pressure in the eye for a short period of time after it is injected. Your doctor will do tests to make sure the pressure in your eye is not elevated persistently after treatment.

Kidney function: Kidney Disease or reduced kidney function may cause Lucentis (Ranibizumab) to build up in the body. If you have reduced kidney function or kidney disease, discuss with your doctor how Lucentis (Ranibizumab) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lucentis (Ranibizumab), and whether any special monitoring is needed.

Vision problems: Lucentis (Ranibizumab) can cause temporary vision problems that may affect your ability to drive or operate machines. If you experience vision problems, do not drive or operate machines until your vision returns to normal.

Pregnancy: Lucentis (Ranibizumab) should not be used during pregnancy unless the benefits outweigh the risks. If there is a chance that you may become pregnant while receiving Lucentis (Ranibizumab), talk to your doctor about whether you should use effective contraception during treatment. If you become pregnant while taking Lucentis (Ranibizumab), contact your doctor immediately.

Breast-feeding: It is not known if Lucentis (Ranibizumab) passes into breast milk. If you are a breast-feeding mother and are taking Lucentis (Ranibizumab), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children and adolescents: The safety and effectiveness of using Lucentis (Ranibizumab) have not been established for children and adolescents.

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All material © 1996-2025 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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