Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Dehydration: Symptoms of nausea, vomiting, and diarrhea may be more common at the start of treatment and can result in loss of fluid from the body. If you experience symptoms of dehydration, such as thirst, decreased urine or tear production, dizziness or headaches, contact your doctor.
Gallstones: Wegovy (Semaglutide) has been associated with an increase in gallstone formation. Gallstones often form when there is significant or fast weight loss. If you experience symptoms of gallstones, such as nausea and vomiting, pain under the right shoulder or between the shoulder blades or severe abdominal pain, contact your doctor as soon as possible.
Heart problems: This medication may increase heart rate and may affect how electrical impulses travel through the heart muscle. If you have heart disease (e.g., recent heart attack, angina, heart failure) or an abnormal heart rhythm (e.g., heart block or fast heart rate), discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Intestinal problems: Wegovy (Semaglutide) may slow down the speed that material passes through the digestive system. If you have digestive system problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Kidney function: Decreased kidney function has been reported with the use of Wegovy (Semaglutide). This may be more likely to occur if you have reduced kidney function when you start using this medication. If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function: The safety and effectiveness of using this medication for people with reduced liver function have not been studied. If you have reduced liver function or liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Low blood glucose (hypoglycemia): People who use Wegovy (Semaglutide) may experience low blood sugar. This may be more likely if you are also taking a sulfonylurea (e.g., glyburide, gliclazide) to control high blood sugar. If you experience symptoms of hypoglycemia such as a cold sweat, nervousness or shakiness, fast heartbeat, headache, hunger, confusion, lightheadedness, weakness, and numbness or tingling of the tongue or lips, contact your doctor.
Pancreatitis (inflammation of the pancreas): Wegovy (Semaglutide) can cause pancreatitis. If you experience symptoms of pancreatitis such as severe and persistent abdominal pain that may move to the back with or without vomiting, contact your doctor immediately. If you have previously had pancreatitis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Thyroid cancer: In rare cases, people have developed thyroid cancer while using Wegovy (Semaglutide). People with a personal or family history of thyroid cancer or people who have multiple endocrine neoplasia syndrome type 2 (a disease where people have tumours in more than one gland in their body) should not use this medication.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Use effective birth control while you are using this medication and for at least 2 months after your last dose of Wegovy (Semaglutide).
Breast-feeding: It is not known if Wegovy (Semaglutide) passes into breast milk. If you are breast-feeding and taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children less than 12 years of age. Adolescents must weigh at least 60 kg or have a BMI of at least 30 kg/m2.
Seniors: Seniors may be at an increased risk of experiencing side effects of Wegovy (Semaglutide).