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What is Lutrepulse?

Lutrepulse (Gonadorelin) belongs to the class of medications called ovulatory agents. Lutrepulse (Gonadorelin) is used to cause ovulation for women who do not have a period.

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Lutrepulse (Gonadorelin) belongs to the class of medications called ovulatory agents. Lutrepulse (Gonadorelin) is used to cause ovulation for women who do not have a period. By promoting ovulation, Lutrepulse (Gonadorelin) helps to improve fertility, helping women to become pregnant. It is used for women who are not producing enough gonadotropin-releasing hormone (GnRH), a hormone released by an area of the brain called the hypothalamus that plays a role in fertility.

Your doctor may have suggested Lutrepulse (Gonadorelin) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using Lutrepulse (Gonadorelin), speak to your doctor. Do not stop using Lutrepulse (Gonadorelin) without consulting your doctor.

Do not give Lutrepulse (Gonadorelin) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use Lutrepulse (Gonadorelin) if their doctor has not prescribed it.



The usual dose of Lutrepulse (Gonadorelin) is 5 µg every 90 minutes injected under the skin or into a vein by an infusion pump. The dose may be increased or decreased according to response and can range between 1 µg and 20 µg. Lutrepulse (Gonadorelin) usually starts to work about 2 to 3 weeks after treatment is started. Treatment is usually continued for another 2 weeks after ovulation occurs.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Your doctor or another health care professional will show you exactly how to mix the medication and use and care for the infusion pump. Once the dose of medication has been prepared, it should be used immediately. Discard any unused material after use. Do not use your injectable solution if it appears cloudy, lumpy, or discoloured. Read the patient information carefully and ask your doctor or health care professional any question you may have.

It is important to use Lutrepulse (Gonadorelin) exactly as prescribed by your doctor. Your doctor will monitor how you are responding to the medication and frequent appointments will be necessary. If the needle comes out or if there is blood in the tubing, contact your doctor.

Store the medication and the sodium chloride to mix with the medication at room temperature in the unopened package. Once the solution is mixed, use it immediately.

Keep Lutrepulse (Gonadorelin) out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.


Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who uses Lutrepulse (Gonadorelin). If you are concerned about side effects, discuss the risks and benefits of Lutrepulse (Gonadorelin) with your doctor.

The following side effects have been reported by at least 1% of people using Lutrepulse (Gonadorelin). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • headache
  • irritation at the site of injection
  • nausea

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • abdominal pain
  • agitation
  • Fever or chills
  • increased menstrual bleeding
  • swelling, pain, itching, redness, or hardening of the skin at the place of injection
  • signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)

Stop using the medication and seek immediate medical attention if any of the following occur:

  • signs of a Anaphylaxis (severe allergic reaction) such as difficulty breathing, flushing, fast heart rate, or itchy skin rash
  • symptoms of ovarian hyperstimulation syndrome (OHSS):
    • abdominal or pelvic discomfort or pain
    • decreased urination
    • Diarrhea
    • difficulty breathing
    • nausea
    • rapid weight gain
    • vomiting

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Lutrepulse (Gonadorelin).


Available form

0.8 mg/vial
Each vial of lyophilized, sterile powder contains 0.8 mg of Lutrepulse (Gonadorelin) acetate providing 0.73 mg of Lutrepulse (Gonadorelin) base. Nonmedicinal ingredients: hydrochloric acid for pH adjustment and 10.0 mg of mannitol as a carrier.

3.2 mg/vial
Each vial of lyophilized, sterile powder contains 3.2 mg of Lutrepulse (Gonadorelin) acetate providing 2.91 mg of Lutrepulse (Gonadorelin) base. Nonmedicinal ingredients: hydrochloric acid for pH adjustment and 10.0 mg of mannitol as a carrier.

Each package also contains 10 mL of sterile isotonic sodium chloride diluents (sodium chloride, water for injection and hydrochloric acid for pH adjustment).



Do not use Lutrepulse (Gonadorelin) if you:

  • are allergic to Lutrepulse (Gonadorelin) or any ingredients of the medication
  • have a medical condition that could be worsened by pregnancy (e.g., certain tumours of the pituitary gland)
  • have a medical condition that could be worsened by reproductive hormones (e.g., estrogen or Progesterone), such as hormone-dependent tumours
  • have ovarian cysts



There may be an interaction between Lutrepulse (Gonadorelin) and any of the following:

  • other medications used to stimulate ovulation

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Lutrepulse (Gonadorelin). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.



Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Lutrepulse (Gonadorelin).

Ovarian hyperstimulation syndrome (OHSS): In rare instances, treatment with Lutrepulse (Gonadorelin) can cause a condition called ovarian hyperstimulation syndrome (OHSS). With OHSS, too many follicles grow, which can cause abdominal or pelvic discomfort or pain, nausea, vomiting, and weight gain. Some women may experience difficulty breathing and diarrhea. OHSS can progress rapidly and may become serious. If you experience any of these symptoms, contact your doctor immediately.

Multiple births: Multiple births may occur with fertility medications. Talk to your doctor about the risks of multiple births before beginning treatment.

Pregnancy: Lutrepulse (Gonadorelin) should be used during pregnancy only as part of the fertility treatment.

Breast-feeding: It is not known if Lutrepulse (Gonadorelin) passes into breast milk. If you are a breast-feeding mother and are taking Lutrepulse (Gonadorelin), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: Lutrepulse (Gonadorelin) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for children.

Seniors: Lutrepulse (Gonadorelin) is intended for use by women of child-bearing age. Its safety and effectiveness have not been established for seniors.

Lutrepulse frequently asked questions

How To Buy Lutrepulse Online?

You can buy Lutrepulse online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Lutrepulse?

You can consult a Canadian doctor online at Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Lutrepulse in Canada?

Shipping cost for Lutrepulse to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada and low dispensing fees to help you get access to treatment.

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You could get Lutrepulse delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

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You can get Lutrepulse for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Lutrepulse for free.

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Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Lutrepulse.

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You need a valid prescription to buy Lutrepulse from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.


All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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