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Persantine (Dipyridamole) belongs to the class of medications called platelet aggregation inhibitors or antiplatelets. It is used to prevent Blood Clots that may occur after a heart valve replacement.
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Persantine (Dipyridamole) belongs to the class of medications called platelet aggregation inhibitors or antiplatelets. It is used to prevent Blood Clots that may occur after a heart valve replacement. It works by preventing certain types of blood cells, called platelets, from sticking together. It is also used for certain types of tests for the heart that examine how well blood is flowing through the heart.
Persantine (Dipyridamole) may be available under multiple brand names and/or in several different forms. Any specific brand name of Persantine (Dipyridamole) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Persantine (Dipyridamole) may not be used for all of the conditions discussed here.
Your doctor may have suggested Persantine (Dipyridamole) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Persantine (Dipyridamole), speak to your doctor. Do not stop taking Persantine (Dipyridamole) without consulting your doctor.
Do not give Persantine (Dipyridamole) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Persantine (Dipyridamole) if their doctor has not prescribed it.
The recommended oral adult dose of Persantine (Dipyridamole) for preventing blood clots is 100 mg 4 times daily one hour before meals. If taken with 1000 mg of Asa daily, the dose of Persantine (Dipyridamole) can be reduced to 25 mg 4 times daily.
When used for medical tests that examine how well blood is flowing through the heart, Persantine (Dipyridamole) is given by injection in a hospital.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take Persantine (Dipyridamole) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store Persantine (Dipyridamole) at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Persantine (Dipyridamole). If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking Persantine (Dipyridamole). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Persantine (Dipyridamole).
Intravenous solution: Each mL contains 5 mg of Persantine (Dipyridamole). Nonmedicinal ingredients: hydrochloric acid, polyethylene glycol, tartaric acid, and sterile water for injection.
Do not take Persantine (Dipyridamole) if you are allergic to Persantine (Dipyridamole) or any ingredients of the medication.
Do not give the injectable form of Persantine (Dipyridamole) to anyone who is in a state of shock or collapse.
There may be an interaction between Persantine (Dipyridamole) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Persantine (Dipyridamole). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Persantine (Dipyridamole).
Liver function: Liver disease or reduced liver function may cause Persantine (Dipyridamole) to build up in the body, causing side effects. If you have liver problems, discuss with your doctor how Persantine (Dipyridamole) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Persantine (Dipyridamole), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Persantine (Dipyridamole).
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.
Low blood pressure: Persantine (Dipyridamole) may cause lowering of blood pressure and increase the effect of blood pressure-lowering medications.
Pregnancy: Persantine (Dipyridamole) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Persantine (Dipyridamole), contact your doctor immediately.
Breast-feeding: Persantine (Dipyridamole) passes into breast milk. If you are a breast-feeding mother and are taking Persantine (Dipyridamole), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
References
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December 18, 2023
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