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August 8, 2022

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Available Form:
inj.powder
Manufacturer name:
sanofi-aventis
Generic name:
thyrotropin
Strength:
0.9MG
Thyrogen (Thyrotropin) alfa belongs to the class of medications called human Thyroid stimulating hormones. It is used with radioactive iodine to treat people with thyroid cancer who have had most or all of their thyroid gland removed without spreading of the cancer to other parts of the body.
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Thyrogen (Thyrotropin) alfa belongs to the class of medications called human Thyroid stimulating hormones. It is used with radioactive iodine to treat people with thyroid cancer who have had most or all of their thyroid gland removed without spreading of the cancer to other parts of the body.
It is also used as an additional diagnostic tool, with or without radioactive iodine, for testing for thyroglobulin (Tg) in the blood in people with thyroid cancer.
Thyrogen (Thyrotropin) alfa is a man-made hormone that acts the same way as the naturally-occurring thyroid stimulating hormone (TSH) in the body. It works by making the thyroid cells in the body produce Tg, absorb radioactive iodine, and remove thyroid tissue left over after surgery.
People who have had surgery to remove their thyroid glands because of thyroid cancer need regular checkups to ensure the cancer is still gone. Testing the blood for Tg is one way to do this. The detection of Tg indicates the presence of thyroid cells or thyroid cancer cells.
Thyrogen (Thyrotropin) may be available under multiple brand names and/or in several different forms. Any specific brand name of Thyrogen (Thyrotropin) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Thyrogen (Thyrotropin) may not be used for all of the conditions discussed here.
Your doctor may have suggested Thyrogen (Thyrotropin) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are using Thyrogen (Thyrotropin), speak to your doctor. Do not stop using Thyrogen (Thyrotropin) without consulting your doctor.
Do not give Thyrogen (Thyrotropin) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to use Thyrogen (Thyrotropin) if their doctor has not prescribed it.
The usual recommended dose is 0.9 mg injected into the buttocks muscle every 24 hours for 2 doses. Thyrogen (Thyrotropin) alfa should only be given as an injection into the muscle. Thyrogen (Thyrotropin) is given by a health care professional with experience managing thyroid cancer.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are using the medication without consulting your doctor.
It is important that Thyrogen (Thyrotropin) be given exactly as recommended by your doctor. If you miss an appointment to receive Thyrogen (Thyrotropin) alfa, contact your doctor as soon as possible to reschedule your appointment.
Thyrogen (Thyrotropin) is stored in the refrigerator and it should be protected from light.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who uses Thyrogen (Thyrotropin). If you are concerned about side effects, discuss the risks and benefits of Thyrogen (Thyrotropin) with your doctor.
The following side effects have been reported by at least 1% of people using Thyrogen (Thyrotropin). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are using Thyrogen (Thyrotropin).
Each vial of sterile, nonpyrogenic lyophilized product contains 1.1 mg of Thyrogen (Thyrotropin) alfa. Nonmedicinal ingredients: mannitol, nitrogen, sodium chloride, sodium phosphate dibasic heptahydrate, sodium phosphate monobasic monohydrate, and sterile water for injection.
Do not use Thyrogen (Thyrotropin) if you:
Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Thyrogen (Thyrotropin).
Heart disease: If you have a history of heart disease and have significant thyroid tissue left after thyroid gland removal, discuss with your doctor how Thyrogen (Thyrotropin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Thyrogen (Thyrotropin), and whether any special monitoring is needed.
Kidney problems: If you have end-stage Kidney Disease or are receiving dialysis treatments, discuss with your doctor how Thyrogen (Thyrotropin) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Thyrogen (Thyrotropin), and whether any special monitoring is needed.
Thyroid cancer patients with metastatic disease: If your thyroid cancer has spread to other parts of the body, especially confined areas (e.g., brain, spinal cord), you may experience local swelling or bleeding at these sites when using Thyrogen (Thyrotropin) alfa. You should talk to your doctor, who may prescribe you corticosteroids (e.g., Dexamethasone) to take before receiving Thyrogen (Thyrotropin) alfa.
Pregnancy: Thyrogen (Thyrotropin) should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while using Thyrogen (Thyrotropin), contact your doctor immediately.
Breast-feeding: It is not known if Thyrogen (Thyrotropin) alfa passes into breast milk. If you are a breast-feeding mother and are using Thyrogen (Thyrotropin), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using Thyrogen (Thyrotropin) have not been established for children.
References
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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