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Tomudex (Raltitrexed) belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as antimetabolites. Tomudex (Raltitrexed) fights cancer by preventing the growth of cancer cells, which eventually results in their destruction.
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Tomudex (Raltitrexed) belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as antimetabolites. Tomudex (Raltitrexed) fights cancer by preventing the growth of cancer cells, which eventually results in their destruction. Tomudex (Raltitrexed) is used to treat colorectal cancer (cancer of the colon and rectum).
Your doctor may have suggested Tomudex (Raltitrexed) for conditions other than the ones listed in these drug information articles. As well, some forms of Tomudex (Raltitrexed) may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Tomudex (Raltitrexed), speak to your doctor. Do not stop taking Tomudex (Raltitrexed) without consulting your doctor.
Do not give Tomudex (Raltitrexed) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Tomudex (Raltitrexed) if their doctor has not prescribed it.
The recommended dose of Tomudex (Raltitrexed) varies according to body size; many things can affect the schedule and dose of medication that a person needs, such as other medical conditions and other medications.
Tomudex (Raltitrexed) is available as an intravenous (into the vein) injection. The medication is usually injected through a specially prepared site on the skin. Tomudex (Raltitrexed) is usually given once every 3 weeks by an intravenous infusion, which usually takes about 15 minutes. If extreme side effects or toxicity occur, the next dose is usually not given until all ill effects from the medication have gone away.
Very careful handling of Tomudex (Raltitrexed) is required. It is always administered in a hospital or similar setting with access to sterile equipment for preparation.
Your doctor may want you to drink extra fluids while taking Tomudex (Raltitrexed) in order to help you pass more fluid and protect your kidneys.
As well as interfering with the genetic material DNA of cancer cells, Tomudex (Raltitrexed) can interfere with some of your normal cells. This may cause a number of side effects such as mouth sores. Keep track of any side effects and report them to your doctor as suggested in the section, "What side effects are possible with Tomudex (Raltitrexed)?"
It is important Tomudex (Raltitrexed) be given exactly as recommended by your doctor. If you miss an appointment to receive Tomudex (Raltitrexed), contact your doctor as soon as possible to reschedule your appointment.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Tomudex (Raltitrexed). If you are concerned about side effects, discuss the risks and benefits of Tomudex (Raltitrexed) with your doctor.
The following side effects have been reported by at least 1% of people taking Tomudex (Raltitrexed). Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Tomudex (Raltitrexed).
Each vial of sterile, lyophilized powder without preservative or bacteriostatic agent contains Tomudex (Raltitrexed) 2 mg (as the disodium salt). Nonmedicinal ingredients: dibasic sodium phosphate, mannitol, nitrogen, and sodium hydroxide. Single dose vials of 2 mg.
Tomudex (Raltitrexed) should not be used by or given to anyone who:
There may be an interaction between Tomudex (Raltitrexed) and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Tomudex (Raltitrexed). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Tomudex (Raltitrexed).
Blood clotting: Tomudex (Raltitrexed) can reduce the number of platelet cells in the blood. Platelets help the blood to clot, and a shortage could make you bleed more easily. Tell your doctor of any signs that your blood is not clotting as quickly. Such symptoms may include black and tarry stools, blood in the urine, easy bruising, or cuts that won't stop bleeding.
Infection: As well as killing cancer cells, Tomudex (Raltitrexed) can reduce the number of cells that fight infection in the body (white blood cells). Avoid contact with people with contagious infections and tell your doctor if you notice signs of an infection, such as fever or chills.
Pregnancy: Tomudex (Raltitrexed) may harm the baby if used during pregnancy. It should not be used during pregnancy, and pregnancy should be avoided (by using effective birth control) during treatment and for at least 6 months after treatment of either parent. If you become pregnant while taking Tomudex (Raltitrexed), contact your doctor immediately.
Breast-feeding: Because of the risks associated with Tomudex (Raltitrexed), a decision should be made to cease breast-feeding or to discontinue the medication, taking into account the importance of the medication to the mother.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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