Frisium (Clobazam) belongs to the class of medications known as benzodiazepines. It is used to treat certain seizure disorders. It is used as an add-on to other antiseizure medications when extra treatment for control of seizures is needed.

Seizures are caused by uncontrolled firing of neurons in the brain (also referred to as increased electrical activity in the brain). Frisium (Clobazam) works by reducing the rate of firing of these neurons.

Frisium (Clobazam) may be available under multiple brand names and/or in several different forms. Any specific brand name of Frisium (Clobazam) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Frisium (Clobazam) may not be used for all of the conditions discussed here.

Your doctor may have suggested Frisium (Clobazam) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Frisium (Clobazam), speak to your doctor. Do not stop taking Frisium (Clobazam) without consulting your doctor.

Do not give Frisium (Clobazam) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Frisium (Clobazam) if their doctor has not prescribed it.

The recommended adult dose of Frisium (Clobazam) ranges from 5 mg to 80 mg daily, as directed by your doctor, taken in 1 or 2 doses with or without food. Doses up to 30 mg daily may be taken as a single daily dose. Higher doses must be split into 2 daily doses. If the dose is divided, the higher portion of the dose should be taken at night. The dose is usually started at 5 mg to 15 mg daily and increased gradually as needed. For children 2 to 16 years, the starting dose should be 5 mg daily, increased gradually to a maximum of 40 mg per day. For children younger than 2 years, the starting dose is based on body weight. If you have reduced liver or kidney function, your doctor may recommend a lower dose.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Frisium (Clobazam) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Frisium (Clobazam) at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Frisium (Clobazam). If you are concerned about side effects, discuss the risks and benefits of Frisium (Clobazam) with your doctor.

The following side effects have been reported by at least 1% of people taking Frisium (Clobazam). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• blurred vision
• Constipation
• decreased interest in sexual activity
• dizziness
• drowsiness
• Dry Mouth
• headache
• loss of appetite
• loss of muscle coordination
• nausea
• nervousness
• tiredness
• weight gain

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Stop taking the medication and seek immediate medical attention if any of the following occur:

• frequent muscle spasms
• slow, shallow, or weak breathing
• symptoms of a serious allergic reaction (e.g., difficulty breathing, Hives, swelling of the face, lips, or throat)
• symptoms of a serious skin reaction (e.g., skin blistering or peeling off; blistering of skin around the lips, eyes, mouth, nose, or genitals; skin rash with fever and muscle or joint pain)
• symptoms of Lupus (red blotchy rash, mainly on the face, with fever, fatigue, nausea, or loss of appetite)
• thoughts of suicide

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Frisium (Clobazam).

Each white, uncoated, round tablet, scored on one side with "B" marked above the score line and "GL" below the score line, and the other side marked with a logo, contains Frisium (Clobazam) 10 mg. Nonmedicinal ingredients: lactose, cornstarch, talc, colloidal silicon dioxide, and magnesium stearate.

Do not take Frisium (Clobazam) if you:

• are allergic to Frisium (Clobazam) or any ingredients of the medication
• are allergic to other benzodiazepines (e.g., Diazepam, Lorazepam)
• are breast-feeding
• are in the first 3 months of pregnancy
• have a history of drug or alcohol dependence
• have acute narrow-angle (closed-angle) Glaucoma
• have Myasthenia Gravis
• have severe breathing problems or Sleep Apnea
• have severe liver impairment

There may be an interaction between Frisium (Clobazam) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

• stop taking one of the medications,
• change one of the medications to another,
• change how you are taking one or both of the medications, or
• leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Frisium (Clobazam). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.