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Tracleer

Tracleer

Bosentan

Tracleer (Bosentan) belongs to a class of medications called endothelin receptor antagonists. Tracleer (Bosentan) is used to treat pulmonary arterial hypertension, which is high blood pressure of the blood vessels between the heart and lungs.

Available form

Tablet

Dosage

62.5mg, 125mg

Manufacturers

Accel Pharma, Accord Healthcare, Actavis Group, Actelion Pharmaceuticals, Alembic Pharmaceuticals, Auro Pharma, Janssen, Marcan Pharmaceuticals, Mylan Pharmaceuticals, Panda Pharmaceuticals

Generic brand of

Bosentan

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Tracleer information

Dosage

Side Effects

Available Form

Contraindications

Precautions

Warnings

The recommended starting dose is 62.5 mg twice daily (once in the morning and once in the evening) for 4 weeks. After 4 weeks, the dose is increased to the recommended maintenance dose of 125 mg twice daily. Tracleer (Bosentan) can be taken with or without food. It should be taken consistently.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Tracleer (Bosentan) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store Tracleer (Bosentan) at room temperature and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Before you begin using a medication, be sure to inform your doctor of any medication conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Tracleer (Bosentan).

Anemia: Tracleer (Bosentan) can reduce the number of red blood cells, which carry oxygen throughout your body. If you experience symptoms of reduced red blood cell count (anemia) such as shortness of breath, feeling unusually tired, or pale skin, contact your doctor as soon as possible.

Your doctor will periodically do blood work to monitor your red blood cell levels to ensure that this does not happen.

Heart failure: People with severe chronic heart failure may see a worsening of their condition when they first start Tracleer (Bosentan). This may be due to fluid retention, which is one of the side effects of Tracleer (Bosentan). If you have severe chronic heart failure, discuss with your doctor how Tracleer (Bosentan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Tracleer (Bosentan), and whether any special monitoring is needed.

Liver problems: Tracleer (Bosentan) can affect your liver. Your doctor will perform regular blood tests to make sure your liver is functioning properly. Tracleer (Bosentan) should not be used by people who have moderately to severely reduced liver function.

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain or swelling, and itchy skin, contact your doctor immediately.

Low blood pressure: If you have low blood pressure, discuss with your doctor how Tracleer (Bosentan) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Tracleer (Bosentan), and whether any special monitoring is needed.

Stopping medication: Suddenly stopping Tracleer (Bosentan) may worsen your symptoms. Do not stop taking Tracleer (Bosentan) unless directed by your doctor. If you are stopping treatment, your doctor will monitor you and reduce the dose over a period of time before stopping the medication completely.

Pregnancy: The medication should not be used during pregnancy, as it may cause serious harm to the fetus. Your doctor should perform a pregnancy test before you start Tracleer (Bosentan), and monthly thereafter while you are taking Tracleer (Bosentan). Since Tracleer (Bosentan) decreases the effectiveness of hormonal birth control, you should use more than one form of contraception (e.g., non-hormonal forms such as condoms) while taking Tracleer (Bosentan). If you become pregnant while taking Tracleer (Bosentan), contact your doctor immediately.

Breast-feeding: It is not known if Tracleer (Bosentan) passes into breast milk. If you are a breast-feeding mother and are taking Tracleer (Bosentan), it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using Tracleer (Bosentan) for children are not well established. Your doctor will determine if the benefits of the medication outweigh the risks for your child.

Seniors: People over 65 years old may be more at risk of side effects from Tracleer (Bosentan) due to age-related decreases in liver function.

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