Before you begin taking a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should take Lysodren (Mitotane).
Drowsiness/reduced alertness: Lysodren (Mitotane) may cause sedation, lethargy, or dizziness. You should exercise caution when driving, operating machinery, or performing other tasks requiring mental alertness.
Liver disease: If you have liver disease, discuss with your doctor how Lysodren (Mitotane) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Lysodren (Mitotane), and whether any special monitoring is needed.
Risk of adrenal insufficiency: Lysodren (Mitotane)'s effect on the adrenal gland may result in the need for steroid replacement therapy during times when your body is under significant stress (e.g., during surgery, trauma, or severe illness).
Pregnancy: The safety of Lysodren (Mitotane) during pregnancy has not been established. Lysodren (Mitotane) should not be used during pregnancy unless the benefits outweigh the risks.
Breast-feeding: Lysodren (Mitotane) passes into breast milk. If you are a breast-feeding mother and are taking Lysodren (Mitotane), it may affect your baby. Lysodren (Mitotane) should not be used during breast-feeding unless the benefits outweigh the risks.
Children: The safety and effectiveness of using Lysodren (Mitotane) have not been established for children under the age of 18 years.