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Delavirdine belongs to the class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is used in combination with other HIV medications to treat the infection caused by the human immunodeficiency virus (HIV).
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Delavirdine belongs to the class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is used in combination with other HIV medications to treat the infection caused by the human immunodeficiency virus (HIV). HIV is the virus responsible for acquired immune deficiency syndrome (AIDS). HIV infection destroys CD4 (T) cells, which are important to the immune system. The immune system helps fight infections.
Reverse transcriptase is a part of HIV required to infect cells and make more virus. Delavirdine prevents reverse transcriptase from working properly, thereby reducing the amount of virus that HIV is able to produce.
Delavirdine does not cure AIDS and does not prevent it from being spread to others. It does slow further growth or reproduction of HIV when used in combination with other medications, and it seems to slow down the destruction of the immune system. This may help to delay the development of problems that are related to AIDS or HIV disease.
Your doctor may have suggested Rescriptor for conditions other than those listed in these drug information articles. As well, some forms of Rescriptor may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking Rescriptor, speak to your doctor. Do not stop taking Rescriptor without consulting your doctor.
Do not give Rescriptor to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Rescriptor if their doctor has not prescribed it.
Your privacy is important. That's why we send your medication inside a plain delivery box so no one will know what's inside.
The recommended adult dose of delavirdine is 400 mg (4 tablets of 100 mg each) 3 times daily taken in combination with other anti-HIV (antiretroviral) medications. Delavirdine tablets can be dissolved in at least 90 mL (3 ounces) of water to make them easier to take. Allow the mixture of water and tablets to stand for a few minutes, then stir the mixture before drinking it. The glass should then be rinsed and the rinse swallowed to make sure that all the medication is taken.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
Rescriptor may be taken with or without food.
If you have a condition known as achlorhydria (low stomach acid), you should take delavirdine with an acidic drink such as orange or cranberry juice. People who need antacids should take them at least one hour apart from their dose of delavirdine.
It is important to take Rescriptor exactly as prescribed. The effectiveness of the medication depends on there being the right amount of delavirdine in the bloodstream. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
If you forget many doses in a row, talk to your doctor about how to resume dosing.
Store Rescriptor at room temperature and protect it from excessive light and moisture. Keep the bottle tightly closed. Keep this and all medication out of reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes Rescriptor. If you are concerned about side effects, discuss the risks and benefits of Rescriptor with your doctor.
The following side effects have been reported by at least 1% of people taking Rescriptor. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Rescriptor.
We sort your medication into clearly labeled, individual packs so you can be sure you're taking the right dose at the right time.
Each white, film-coated, capsule-shaped tablet marked with "U 3761" contains delavirdine mesylate 100 mg. Nonmedicinal ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, lactose, magnesium stearate, microcrystalline cellulose, propylene glycol, and titanium dioxide.
Do not take Rescriptor if you:
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There may be an interaction between delavirdine and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with Rescriptor. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Rescriptor.
Fat redistribution: Over time Rescriptor may change how fat is distributed in your body and may change your body shape. You may notice increased fat in the upper back and neck, breast, around the back, chest, and stomach area; or loss of fat from the legs, arms, and face. The long-term effects of this are not known.
Liver function: Delavirdine is removed from the body by the liver and may cause liver problems. If you have liver disease or decreased liver function, discuss with your doctor how Rescriptor may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Rescriptor, and whether any special monitoring is needed.
If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, or abdominal pain, contact your doctor as soon as possible.
Skin rash: A temporary skin rash may appear within 1 to 3 weeks after starting treatment with delavirdine. The rash usually goes away in about 3 to 14 days and can be treated without stopping treatment with delavirdine.
Stopping the medication: If you stop taking Rescriptor, your HIV infection could get worse. Take the medication exactly as prescribed by your doctor, and do not stop taking the medication without checking with your doctor first.
Pregnancy: Studies demonstrating the safety and effectiveness of using Rescriptor during pregnancy are not available. Rescriptor should not be used during pregnancy unless the potential benefits outweigh risks. If you become pregnant while taking Rescriptor, contact your doctor immediately.
Breast-feeding: It is not known if delavirdine passes into breast milk. However, since HIV can be transmitted by breast milk, women who have HIV should not breast-feed.
Children: The safety and effectiveness of delavirdine has not been established for children younger than 16 years old.
We manage your refills and get in touch with your doctors for prescription renewals so that you always have the medication you need.
All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.
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