Temodal

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Manufacturer name:  

Merck

Generic name:  

TEMOZOLOMIDE

Strength:  

5MG

What is Temodal?

Temodal (Temozolomide) belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as alkylating agents. Temodal (Temozolomide) prevents the growth of cancer cells by interfering with the genetic material DNA, which is necessary for the reproduction of cells.

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Temodal frequently asked questions

How To Buy Temodal Online?

You can buy Temodal online at PocketPills if you already have a valid prescription from your doctor. You can get started by uploading your prescription, ordering a refill by transferring any existing medications to our pharmacy or talking to one of our Canadian Doctors to get an online prescription. Get started now!

How To Get a Prescription for Temodal?

You can consult a Canadian doctor online at pocketpills.com. Our physicians can prescribe medications online during your consultation. Once you receive a prescription, you'll have the option to have it delivered to your door in discreet packaging and at no additional cost!. Click here to get an online prescription today!

Can I Get Same-Day Delivery?

Yes! We do provide same-day delivery in select areas. We do next business day delivery and can also ship overnight as well.

How Much is Shipping Cost for Temodal in Canada?

Shipping cost for Temodal to you in Canada is zero. Pocketpills offers FREE shipping anywhere in Canada to help you get access to treatment.

How to get Temodal delivered to my home?

You could get Temodal delivered at your doorstep from us in Canada if you ordered prescription medications with a valid prescription. If you are not sure if we deliver to your area, contact us.

How to get Temodal in Canada for free?

You can get Temodal for free in Canada if your health insurance provider covers it fully. Contact your provider or us to help you find out if you qualify to get Temodal for free.

Can I consult a doctor online to get Temodal?

Yes. You can book a consultation online with a Canadian doctor here with us at PocketPills to see if you qualify for a prescription to order Temodal.

Can I buy Temodal without a prescription?

You need a valid prescription to buy Temodal from us. Contact us if you need a prescription. One of our doctors can give you a telephone call at your convenience.

Temodal How to Take

Temodal (Temozolomide) belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the group of antineoplastics known as alkylating agents. Temodal (Temozolomide) prevents the growth of cancer cells by interfering with the genetic material DNA, which is necessary for the reproduction of cells. Because cancer cells reproduce more quickly than normal cells, cancerous cells are targeted by the medication. Temodal (Temozolomide) is used to treat specific types of brain tumours.

Temodal (Temozolomide) may be available under multiple brand names and/or in several different forms. Any specific brand name of Temodal (Temozolomide) may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of Temodal (Temozolomide) may not be used for all of the conditions discussed here.

Your doctor may have suggested Temodal (Temozolomide) for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking Temodal (Temozolomide), speak to your doctor. Do not stop taking Temodal (Temozolomide) without consulting your doctor.

Do not give Temodal (Temozolomide) to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take Temodal (Temozolomide) if their doctor has not prescribed it.

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Discreet Packaging

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Temodal Dosage

The recommended dose of Temodal (Temozolomide) varies according to body surface area, and takes into account whether you have been previously treated with chemotherapy. Before each new cycle of treatment, your blood will be tested and your dose of Temodal (Temozolomide) may change depending on the test results.

Temodal (Temozolomide) is normally taken once a day for 5 days followed by a rest period of 23 days. This 28-day cycle is repeated until treatment is complete, as assessed by your doctor.

For a specific type of newly diagnosed brain tumour called glioblastoma multiforme, Temodal (Temozolomide) is given daily along with radiation for 42 days. 4 weeks after radiation is complete, 6 cycles of 28 days of treatment with Temodal (Temozolomide) are started.

Temodal (Temozolomide) capsules should be swallowed whole, with a full glass of water at least one hour before a meal. Do not open or chew the capsules. In case of accidental contact with the capsule contents, flush the area with water.

Antinausea medications can be taken just before or after Temodal (Temozolomide) to help reduce the risk of vomiting. If vomiting occurs after taking the medication, do not take a second dose. Contact your doctor for further instructions.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to take Temodal (Temozolomide) exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, check with your doctor. Do not take a double dose to make up for a missed one, unless your doctor tells you to do so.

Store Temodal (Temozolomide) at room temperature, protect it from moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Temodal Side Effects

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes Temodal (Temozolomide). If you are concerned about side effects, discuss the risks and benefits of Temodal (Temozolomide) with your doctor.

The following side effects have been reported by at least 1% of people taking Temodal (Temozolomide). Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abdominal pain
  • blurred vision
  • changes in taste perception
  • Constipation
  • Diarrhea
  • dizziness
  • drowsiness
  • fatigue
  • hair loss
  • headache
  • itching
  • joint pain
  • lack of energy
  • loss of appetite
  • muscle weakness
  • nausea
  • rash
  • tingling sensation
  • trouble sleeping
  • weakness
  • weight loss
  • vomiting

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • anxiety
  • burning, prickling, or tingling sensations in the hands or feet
  • confusion
  • difficulty speaking
  • hearing impairment
  • increased blood sugar (e.g., frequent urination, increased thirst, excessive eating, unexplained weight loss, poor wound healing, infections, fruity breath odour)
  • memory problems
  • mouth sores or inflammation
  • pain, bruising, irritation, itching, warmth, swelling, or redness at the injection site
  • rapid mood changes
  • rash with skin swelling, including on the palms of the hands and soles of the feet (if you are not having difficulty breathing)
  • shortness of breath and cough
  • signs of Anemia (low red blood cells; e.g., dizziness,  pale skin, unusual tiredness or weakness, shortness of breath)
  • signs of bleeding (such as easy bruising, bleeding gums, nosebleeds, vomiting blood, blood in the urine, dark tarry stools)
  • signs of Depression (e.g., poor concentration, changes in weight, changes in sleep, decreased interest in activities, thoughts of suicide)
  • signs of infection (Fever, chills, cough, sore throat)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • pneumonia (symptoms such as cough that does not go away, or trouble breathing and fever)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • seizures
  • signs of an allergic reaction (such as difficulty breathing, Hives, or swelling of the face or throat)
  • signs of bleeding in the stomach (e.g., bloody, black, or tarry stools, spitting up of blood, vomiting blood or material that looks like coffee grounds)
  • signs of a severe skin reaction such as blistering, peeling, a rash covering a large area of the body, a rash that spreads quickly, or a rash combined with fever or discomfort
  • swelling of the hands or feet with shortness of breath
  • symptoms of herpes simplex encephalitis (e.g., fever, headache, personality changes, seizures, vomiting)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking Temodal (Temozolomide).

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Temodal Available Form

Capsules

5 mg
Each size 3 capsule, with opaque green cap and opaque white body, the cap imprinted in black ink with "TEMODAL", the body imprinted in black ink with 2 stripes, "5 mg", and the Schering-Plough logo, contains 5 mg of Temodal (Temozolomide). Nonmedicinal ingredients: colloidal silicon dioxide, lactose anhydrous, sodium starch glycolate, stearic acid and tartaric acid; capsule shells: FD&C Blue No. 2, gelatin, sodium lauryl sulfate, titanium dioxide and yellow iron oxide; ink: shellac, propylene glycol, ammonium hydroxide, black iron oxide, and sometimes potassium hydroxide.

20 mg
Each size 2 capsule, with yellow cap and opaque white body, the cap imprinted in black ink with "TEMODAL", the body imprinted in black ink with 2 stripes, "20 mg", and Schering-Plough logo, contains 20 mg of Temodal (Temozolomide). Nonmedicinal ingredients: colloidal silicon dioxide, lactose anhydrous, sodium starch glycolate, stearic acid and tartaric acid; capsule shells: gelatin, sodium lauryl sulfate, titanium dioxide and yellow iron oxide; ink: shellac, propylene glycol, ammonium hydroxide, black iron oxide, and sometimes potassium hydroxide.

100 mg
Each size 1 capsule, with opaque pink cap and opaque white body, the cap imprinted in black ink with "TEMODAL", the body imprinted in black ink with 2 stripes, "100 mg", and the Schering-Plough logo, contains 100 mg of Temodal (Temozolomide). Nonmedicinal ingredients: colloidal silicon dioxide, lactose anhydrous, sodium starch glycolate, stearic acid and tartaric acid; capsule shells: gelatin, sodium lauryl sulfate, red iron oxide and titanium dioxide; ink: shellac, propylene glycol, ammonium hydroxide, black iron oxide, and sometimes potassium hydroxide.

140 mg
Each size 0 capsules with a blue cap and opaque white body, the cap imprinted in black ink with "TEMODAL'', the body imprinted in black ink with 2 stripes, "140 mg", and the Schering-Plough logo, contains 140 mg of Temodal (Temozolomide). Nonmedicinal ingredients: colloidal silicon dioxide, lactose anhydrous, sodium starch glycolate, stearic acid and tartaric acid; capsule shells: FD&C blue No. 2, gelatin, sodium lauryl sulfate and titanium dioxide; ink: shellac, propylene glycol, ammonium hydroxide, black iron oxide, and sometimes potassium hydroxide.

250 mg
Each size 0 capsule, with opaque white cap and opaque white body, the cap imprinted in black ink with "TEMODAL", the body imprinted in black ink with 2 stripes, "250 mg" and the Schering-Plough logo, contains 250 mg of Temodal (Temozolomide). Nonmedicinal ingredients: colloidal silicon dioxide, lactose anhydrous, sodium starch glycolate, stearic acid and tartaric acid; capsule shells: gelatin, sodium lauryl sulfate and titanium dioxide; ink: shellac, propylene glycol, ammonium hydroxide, black iron oxide, and sometimes potassium hydroxide.

Temodal Contraindications

Do not use Temodal (Temozolomide) if you:

  • are allergic to Temodal (Temozolomide) or any ingredients of Temodal (Temozolomide)
  • are allergic to Dacarbazine (DTIC)
  • have severely reduced bone marrow function
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Temodal Precautions

There may be an interaction between Temodal (Temozolomide) and any of the following:

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with Temodal (Temozolomide). Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the Nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

Temodal Warnings

Before you begin using a medication, be sure to inform your doctor of any medical conditions or Allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use Temodal (Temozolomide).

Birth defects: Temodal (Temozolomide) can have genotoxic effects, meaning that it may damage the genetic material contained in sperm. This could lead to birth defects. If you are a man being treated with Temodal (Temozolomide), you should not father a child during treatment and for up to 6 months after treatment.

Blood disorders: Temodal (Temozolomide) can cause the levels of certain blood cells to drop. This may lead to problems with blood clotting, the immune system, or the transport of oxygen through the body. Contact your doctor immediately if you develop a fever, chills, easy bruising, paleness, or bleeding (symptoms may include black and tarry stools, blood in the urine, or cuts that won't stop bleeding) while taking Temodal (Temozolomide). Your doctor will arrange periodic blood testing to monitor various blood components.

Hepatitis B infection: Temodal (Temozolomide) has been linked to reactivation of Hepatitis B infection. If you have had hepatitis B in the past discuss with your doctor how Temodal (Temozolomide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Temodal (Temozolomide), and whether any special monitoring is needed.

Kidney function: The safety and effectiveness of using Temodal (Temozolomide) have not been established for people with kidney problems. You should be closely monitored by your doctor if you have kidney problems.

Liver function: Temodal (Temozolomide) may reduce liver function and can cause liver failure, including death. If you have liver problems, discuss with your doctor how Temodal (Temozolomide) may affect your medical condition, how your medical condition may affect the dosing and effectiveness of Temodal (Temozolomide), and whether any special monitoring is needed. Your doctor may want to test your liver function regularly with blood tests while you are taking Temodal (Temozolomide).

If you experience symptoms of liver problems such as fatigue, feeling unwell, loss of appetite, nausea, yellowing of the skin or whites of the eyes, dark urine, pale stools, abdominal pain, or swelling, and itchy skin, contact your doctor immediately.

Male infertility: Irreversible infertility may result from treatment with Temodal (Temozolomide). Therefore, men who may want to father a child in the future should seek advice on cryoconservation (freezing for long-term storage) of sperm prior to starting treatment.

Pneumocystis carinii pneumonia (PCP): People who take Temodal (Temozolomide) daily along with radiation may be at a higher risk of developing a serious form of pneumonia called Pneumocystis carinii pneumonia (PCP). If you are taking Temodal (Temozolomide) daily along with radiation, your doctor will prescribe medication to help prevent PCP.

Vomiting: Nausea and vomiting are very common with Temodal (Temozolomide) treatment. Antinausea medications taken before or after taking Temodal (Temozolomide) may be recommended.

Pregnancy: Temodal (Temozolomide) may harm the baby if used during pregnancy. Women should avoid becoming pregnant while taking Temodal (Temozolomide). Use effective birth control while using Temodal (Temozolomide) and for 6 months after stopping the medication. Tell your doctor immediately if you become pregnant.

Breast-feeding: It is not known if Temodal (Temozolomide) passes into breast milk. It is recommended that women should stop breast-feeding while taking Temodal (Temozolomide).

Children: The safety and effectiveness of using Temodal (Temozolomide) have not been established for children.

Seniors: People over the age of 70 are more likely to experience a decrease in white blood cell counts or platelet cells. This can affect their body's ability to fight infection or their blood's ability to clot.

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References

All material © 1996-2021 MediResource Inc. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health providers with any questions you may have regarding a medical condition.

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