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What is Bupropion XL?


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What is Bupropion XL?

Bupropion XL is a prescription drug that comes in the form of an extended-release tablet to be taken by mouth. As it is an extended-release tablet, it is released in your body slowly.

What are the uses of Bupropion XL?

Bupropion is an antidepressant. It triggers the activity of natural chemicals in your brain, such as norepinephrine and dopamine, which are responsible for improving your mood. The nerves take up these chemicals to send messages among them. Bupropion is thus used to manage:

  • Depression
  • Seasonal affective disorder (SAD)
It can also be used to help you stop smoking.

How do you use Bupropion XL?

Bupropion XL is a medication to be taken by mouth. Read the medication guide before taking it.Here are certain things to know before taking it:

  • Take the tablet orally as directed by your doctor. It is usually taken once in a day, preferably in the morning.
  • Take the exact dose as prescribed by your doctor. Do not use it too often or take a higher dose than advised.
  • Swallow the whole tablet.
  • Do not chew or crush the tablet. Doing so will release all the medicine at once, increasing the probability of side-effects.
  • Do not split the tablet unless told by your doctor or pharmacist.
  • Avoid taking it late in the day as it may cause trouble sleeping.
  • In case you have an upset stomach, take the medication after or with a snack or meal.
  • Take medicine regularly, preferably at the same time every day. Do not skip the medication without consulting your doctor.
If you forget a dose:
  • Take it as soon as you remember it the same day and carry on as usual from the next day
  • If you completely forget the dose for the whole day, skip it and carry on, as usual, the next day
  • Do not take double the dose to compensate for the missed dose

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Bupropion frequently asked questions

When should you not take Bupropion?

You should not take Bupropion if:

  • It has passed the expiry date of the medicine printed on the pack.
  • The packaging shows signs of tampering.
You should also not take Bupropion if you had drinks with alcohol. It may increase the risk of seizures.

Who should not take Bupropion?

This medication should be avoided by pregnant and breastfeeding moms unless suggested by the doctor. You should also avoid this medicine if you have:

  • Kidney disorders
  • Liver diseases
  • Angle-closure glaucoma
  • Bipolar disorders
  • Eating disorders such as bulimia or anorexia
  • Seizures
You should also not take Bupropion if you are on the following medications:
  • Monoamine oxidase inhibitors, such as selegiline and phenelzine
  • Antidepressants, such as nortriptyline, desipramine, fluoxetine, venlafaxine, imipramine, and paroxetine
  • Antipsychotics, such as risperidone, haloperidol, and thioridazine
  • Anti-arrhythmics, such as flecainide and propafenone
  • HIV drugs, such as ritonavir, efavirenz, and lopinavir
  • Anti-seizure drugs, such as phenobarbital, carbamazepine, and phenytoin
  • Beta-blockers
  • Theophylline
  • Amantadine
  • Levodopa
  • Corticosteroids
  • Clopidogrel
This is not an exhaustive list. Always consult a doctor before taking Bupropion if you are on any other medications.

What are the side-effects and risks of Bupropion?

Bupropion is not seen to cause drowsiness, but it can cause other side-effects. Some commonly occurring side-effects are:

  • Dryness of mouth
  • Headache
  • Nausea and vomiting
  • Sweatiness
  • Blurred vision
  • Confusion
  • Rapid heartbeat
  • Abnormal heart rhythms
  • Agitation
  • Constipation
  • Dizziness
  • Shakiness
  • Trouble sleeping
  • Rash
These are mild symptoms and usually resolve on their own. Severe side-effects include:
  • Mental health
  • Attempt to suicide
  • Worsened or new anxiety
  • Worsened or new depression
  • Suicidal thoughts
  • Panic attacks
  • Impulsiveness
  • Getting angry, aggressive, or violent
  • Increased talking and activity
Eye Problems
  • Redness or swelling around the eyes
  • Eye pain
  • Double or blurred vision
  • Staring spells
  • Confusion
  • Loss of consciousness
  • Jerking movements of arms and legs
This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

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